African Journal of
Pharmacy and Pharmacology

  • Abbreviation: Afr. J. Pharm. Pharmacol.
  • Language: English
  • ISSN: 1996-0816
  • DOI: 10.5897/AJPP
  • Start Year: 2007
  • Published Articles: 2145

Table of Content: January 2010; 4(1)

January 2010

Ethno medicinal information on collation and identification of some medicinal plants in Research Institutes of South-west Nigeria

An arboretum is a collection of trees. Related collections include a fruticetum (from the Latin frutex, meaning shrub), and a viticetum, a collection of vines. More commonly today, an arboretum is a botanical garden containing living collections of woody plants intended at least partly for scientific study. Distribution of medicinal plants information were investigated in International Institute...

Author(s): I. O. Lawal, N. E. Uzokwe, A. B. I. Igboanugo, A. F. Adio, E. A. Awosan, J. O. Nwogwugwu, B. Faloye, B. P. Olatunji and A. A. Adesoga      

  • Article Number: 5EE8E8E29096

January 2010

The water decoction of Aristolochia debilis Sieb.et Zucc induces renal toxic effects in rats

The present study was designed to investigate toxic effects of different concentration of the Aristolochia debilis Sieb. et Zucc. on renal functions in rats. Wistar rats were randomly divided into low dosage group (treated with A. debilisSieb.et Zucc at a dose of 0.81 g.kg-1.d-1 for three months), moderate dosage group (at a dose of 4.05 g.kg-1.d-1), high dosage group (at a dose of 8.1 g.kg-1.d-1)...

Author(s): Li-Qun Song, Xiao-Peng Ma, Li-Zhe Wang, Yu Qiao, Ye-Xu Song and Yan-Chun Ma    

  • Article Number: 783CC9629189

January 2010

Cytotoxicity of extracts from fruit plants against leukemic cell lines

This study examined the antileukemic activity of non edible parts of 13 common Thai tropical fruits. Their ethanolic extracts were tested for cytotoxic effects on U937, K562, HL60, Molt 4 and normal human peripheral blood mononuclear cells (PBMCs). Three of 20 crude plant extracts (kaffir lime leaves, mangosteen peels, and wampee leaves) had strong cytotoxic effects on K562, U937, and Molt4 cells. The...

Author(s): Chadarat Ampasavate, Siriporn Okonogi and Songyot Anuchapreeda    

  • Article Number: 75AA58229220

January 2010

Protective effect of quercetin against necrosis and apoptosis induced by experimental ischemia and reperfusion in rat liver

Quercetin is a well-known flavonoid and a strong antioxidant. Quercetin an important flavonoid possesses beneficial effects on health due to its antioxidant function. One mechanism of the antioxidant action of quercetin was involved in scavenging free radicals, such as superoxide radicals generated by xanthine and xanthine oxidase. To study the effect of quercetin on apoptosis and necrosis induced by 1 h ischemia...

Author(s): khaki Arash      

  • Article Number: DAA32AA29256

January 2010

Protective effect of quercetin against necrosis and apoptosis induced by experimental ischemia and reperfusion in rat liver

Quercetin is a well-known flavonoid and a strong antioxidant. Quercetin an important flavonoid possesses beneficial effects on health due to its antioxidant function. One mechanism of the antioxidant action of quercetin was involved in scavenging free radicals, such as superoxide radicals generated by xanthine and xanthine oxidase. To study the effect of quercetin on apoptosis and necrosis induced...

Author(s): khaki Arash    

  • Article Number: DF651FB29322

January 2010

Introducing pharmacoeconomics (PE) in medical undergraduate curriculum

Increasing health care cost is a major concern in developing world. Patients are affected by the high pricing of drugs and though the symptoms improve the poor patient compliance sets in if the regimen is heavy on the pocket of the patient. Therefore, concept  of Pharmacoeconomics  are essential for physicians to prescribe individualized drug therapy based on essential drug concept, STEP...

Author(s): Ujjwala Kulkarni, Y. A. Deshmukh, V. V. Moghe, Nima Rege and Madhuri Kate    

  • Article Number: 59827D529347

January 2010

Analysis of the correlation between morning sickness and rhesus status in pregnant women in Nigeria

Erythroblastosis fetalis is a haemolytic disease of the rhesus negative [Rh- ]  mother after the first gestation of a[ Rh+] neonate. Morning sickness (MS) describes a series of neuro-endocrine disturbances characterized by nausea, hyperemesis gravidarum, nutritional selectivity, general debility, confusion and sometimes coma, especially in early pregnancy. It may be mild, moderate or severe and if managed...

Author(s): G. Oze, R. Oze, B. Anyaehie, H. Nwanjo, P. Nwankpa, S. Ezekwe, M. Okafor, G. Ojiegbe, I. Okoro and A. Orjiako    

  • Article Number: 8B428AC29382