July 2023

Effects of traditional remedy Sarenta and glibenclamide combination on hyperglycemia orally induced in rats

Herbal preparations are commonly used by low-income populations to treat diabetes. The objective of this work was to evaluate interaction between Sarenta remedy with antidiabetic drug such as glibenclamide. Experimental study was carried out according to protocol described by Kambouche.  Before giving different solutions on study, baseline blood glucose was taken using "One call plus" glucometer, then...

Author(s): Kouakou Sylvain, Yapo Guy, Djadji Ayoman, Adehouni Yacouba, Kouakou-Siransy G. and Irié-N’Guessan G.  

July 2023

Variation of antioxidant and antibacterial activities of ethanolic extracts of propolis in three bee-keeping agro-ecological zones of Uganda

Propolis is a resinous plant material collected by bees to defend their colony. This study evaluated the antibacterial and antioxidant activities of ethanolic extracts of Ugandan propolis in three bee-keeping agro-ecological zones. Antibacterial assays were performed on two Gram-positive (S. aureus and S. pneumoniae) and two Gram-negative (E. coli and P. aeruginosa) bacteria within a concentration range of ~1.6 to 100...

Author(s): Julius Kyomya, Mariam Kaanyi Kirabo, Wilberforce John Mayoka, Rehema Namunyenga, Rogers Jaggwe, Lawrence Imanirampa, and Jonans Tusiimire,  

July 2023

Assessment of antibiotics use and associated problems at Jimma Health Center, South West Ethiopia

Misuse of antibiotics is the main cause for resistance development. The objective of this study is to assess patterns of antibiotics use and associated problems at Jimma Health Center. The study was conducted from February 25, 2016 to March 25, 2016. For the analysis of prescribing indicators retrospectively 295 patient charts that fulfills inclusion criteria were systematically selected from a total of 9800 charts from...

Author(s): Geremew Kinati Terfa and Gemechu Zeleke  

July 2023

Synthesis of organic compounds using yellow yam (Dioscorea praehensilis) tyrosinase as catalyst

The authors report the synthesis of some bioactive organic compounds which could be of pharmacological interest using Dioscorea praehensilis tyrosinase immobilized on calcium-alginate beads. The enzymatic synthesis of these compounds involved pyruvic acid as a source of carbonyl groups, ammonia and catechol. Catechol was used as substrate and a parent compound that supplied aromatic ring carbons for the reactions. The...

Author(s): Olutosin Samuel Ilesanmi, Omowumi Funke Adedugbe, David Adeniran Oyegoke, Victory Ayo Olagunju and Isaac Olusanjo Adewale