May 2022

Development of novel preparation method for rapid release of paclitaxel as a dry powder for inhalation: A preparation method for dry powder inhalers

The purpose of this experiment was to develop a novel dry powder inhalation preparation method. Paclitaxel dry powder for inhalation was prepared by spraying a paclitaxel-ethanol solution directly onto an inhalable lactose carrier. This process was carried out under a relatively low temperature, avoiding potential damage to the drug from exposure to high temperatures. After preparation, the particle morphology, size,...

Author(s): Wenxiu Hong,, Rongfeng Hu, Tori Czech, Qingrong Xia,, Jun Liang,, and Jihui Tang  

May 2022

Antibacterial activities of Bidens pilosa L, Hoslundia opposita Vahl, and Ageratum conyzoides L against some common wound pathogens

Bacterial infection cause delayed wound healing, and the rising cases of antibiotic resistance call for alternative solutions. This research aims to determine and compare the antibacterial activity of selected research plants when extracted by different methods using different solvents. The plants were extracted with ethanol, methanol, acetone, water, chloroform, and ethyl acetate using Soxhlet and maceration...

Author(s): Catherine Namuga, Haruna Muwonge, Margaret Lubwama, Nakyejwe Janet, Tahalu Sekulima and John Baptist Kirabira  

May 2022

Assessment of the immunomodulatory activity of Artavol® aqueous extract in Plasmodium berghei infected mice

ARTAVOL® is an herbal product derived from de-artemisinised extracts of Artemisia annua combined with lemon grass extract and avocado seed powder as a base locally used in Uganda for malaria prevention. This study assessed the immunomodulatory activity of the aqueous extract of Artavol® in Plasmodium berghei infected mice. The immunomodulatory activity of the aqueous extract of Artavol® was evaluated on...

Author(s): Martin Amanya, Clement Olusoji Ajayi, Bernard Natukunda, Francis Wasswa, Alice Bayiyana, Rose Nabatanzi, Obondo Sande and Amon Agaba