Full Length Research Paper
Abstract
The aim of this research was to study genetic polymorphism in growth hormone (GH) locus and its association with body weight of 43 Grati dairy cows ranging from 2 to 4 years old. Polymorphism of GH locus was ascribed using a PCR-RFLP method involving restricted enzyme Msp1 on 2% agarose gel. All data were subjeced to statistical analysis based on one way classification model using a statistical software package of Genstat 200 version 2. The results showed that frequencies of normal allel (Msp1+) and mutant allel (Msp-) were 0.34 and 0.66 respectively with 0.22 polymorphism was found in this locus. There was significant relationship between Msp1+/Msp1+, Msp1+/Msp1- and Msp1-/Msp1- genotypes and body weight (P < 0.05) but Msp1+/Msp1+ and Msp1+/Msp1- genotypes had a stronger correlation to the higher body weight than Msp1-/Msp1- genotype.
Key words: Grati cows, polymorphism, growth hormone, body weight.
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