International Journal of
Water Resources and Environmental Engineering

  • Abbreviation: Int. J. Water Res. Environ. Eng.
  • Language: English
  • ISSN: 2141-6613
  • DOI: 10.5897/IJWREE
  • Start Year: 2009
  • Published Articles: 347

Full Length Research Paper

Evidence based review of Legionella elimination in building water systems

M. D. Sedzro*
  • M. D. Sedzro*
  • Marine Engineering Department, Faculty of Engineering, Regional Maritime University, Ghana.
  • Google Scholar
R. A. Banu
  • R. A. Banu
  • Water Research Institute, Environmental Biology and Health, Accra, Ghana.
  • Google Scholar
M. O. Akrong
  • M. O. Akrong
  • Water Research Institute, Environmental Biology and Health, Accra, Ghana.
  • Google Scholar


  •  Received: 26 September 2015
  •  Accepted: 29 August 2016
  •  Published: 31 January 2017

References

Aalst MV, Adger N, Arent D, Barnett J, Betts R, Bilir E, Yoh G (2014). Climate Change 2014: Impacts, Adaptation, and Vulnerability. Assess. Rep. 5(October 2013):1-76.

 

Abad FX, Pinto RM, Diez JM, Bosch A (1994). Disinfection of human enteric viruses in water by copper and silver in combination with low levels of chlorine. Appl. Environ. Microbiol. 60(7):2377-2383.

 

Altherr AM, Mosler HJ, Tobias R, Butera F (2008). Attitudinal and relational factors predicting the use of solar water disinfection: a field study in Nicaragua. Health Edu. Behav. Official Pub. Soc. Public Health Educ. 35(2):207-220.
Crossref

 

Beer CW, Guilmartin LE, McLoughlin TF, White TJ (1999). Swimming pool disinfection: efficacy of copper/silver ions with reduced chlorine levels. J. Environ. Health 61(9):9-13.

 

Benhamimed EA, Moulessehoul S (2010). L'hyperchloration de l'eau de robinet et cancer de la vessie dans la r??gion de Mostaganem (Ouest alg??rien). J. Afr. Du Cancer 2(3):1-6.

 

Blanc DS, Carrara P, Zanetti G, Francioli P (2005a). Water disinfection with ozone, copper and silver ions, and temperature increase to control Legionella: seven years of experience in a university teaching hospital. J. Hosp. Infect. 60(1):69-72.
Crossref

 

Borella P, Guerrieri E, Marchesi I, Bondi M, Messi P (2005). Water ecology of Legionella and protozoan: Environmental and public health perspectives. Biotechnol. Ann. Rev. 11:355-380.
Crossref

 

Botzenhart K, Tarcson GOM (1993). Inactivation of Bacteria and Coliphages by Ozone and Chlorine Dioxide in a Continuous Flow Reactor. Water Sci. Technol. 27(3-4).

 

Brahmi M, Hassen A (2014). Modeling of ultraviolet (UV) radiation under a large pilot-scale designed for wastewater disinfection and inactivation of selected bacteria of Pseudomonas aeruginosa in a laboratory UV device. Afr. J. Microbiol. Res. 8(16):1735-1748.
Crossref

 

Cachafeiro SP, Naveira IM, García IG (2007). Is copper-silver ionisation safe and effective in controlling legionella? J. Hosp. Infect. 67(3):209-216.
Crossref

 

Campos C, Loret JF, Cooper AJ, Kelly RF (2003). Disinfection of domestic water systems for Legionella pneumophila. J. Water Supply: Res. Technol. AQUA 52(5):341-354.

 

Cantor KP (1997). Drinking water and cancer. Cancer Causes Control. 8(3):292-308.
Crossref

 

Casey S, Collen M, Lake A (1998). Ozone disinfection. 

View

 

CDC (2016). Legionella (Legionnaires' Disease and Pontiac Fever). 

View

 

Centre for Respiratory Diseases and, Meningitis, and Division of Public Health, S., and Response, (NICD) (2016). RESPIRATORY DISEASE; Three travel-associated Legionnaires' disease (TALD) cases associated with a hotel in Cape Town. 

 

Chen YS, Lin YE, Liu YC, Huang WK, Shih HY, Wann SR, Chang CL (2008). Efficacy of point-of-entry copper-silver ionisation system in eradicating Legionella pneumophila in a tropical tertiary care hospital: implications for hospitals contaminated with Legionella in both hot and cold water. J. Hosp. Infect. 68(2):152-158.
Crossref

 

Chen YS, Liu YC, Lee SSJ, Tsai HC, Wann SR, Kao CH, Lin YSE (2005). Abbreviated duration of superheat-and-flush and disinfection of taps for Legionella disinfection: Lessons learned from failure. Am. J. Infect. Control 33(10):606-610.
Crossref

 

Chevrefils G, Caron É, Wright H, Sakamoto G (2006). UV dose required to achieve incremental log inactivation of bacteria, protozoa and viruses. IUVA News 8(1):38-45.

 

Choi Y, Choi YJ (2010). The effects of UV disinfection on drinking water quality in distribution systems. Water Res. 44(1):115-122.
Crossref

 

Clancy JL, Bukhari Z, Hargy TM, Bolton JR, Dussert BW, Marshall MM (2000). Using UV to inactivate Cryptosporidium. J. Am. Water Works Assoc. 92(9):97-104.

 

Cold Spring Harbor Laboratory (2008). Worldwide-distributed Clone Of Bacteria Responsible For Legionnaire's Disease Identified. Retrieved August 15, 2016. 

View

 

Conroy RM, Meegan ME, Joyce T, McGuigan K, Barnes J (2001). Solar disinfection of drinking water protects against cholera in children under 6 years of age. Arch. Dis. Childhood 85(4):293-295.
Crossref

 

Cooper IR, Hanlon GW (2010). Resistance of Legionella pneumophila serotype 1 biofilms to chlorine-based disinfection. J. Hosp. Infect. 74(2):152-159.
Crossref

 

Dankovich TA, Gray DG (2011). Bactericidal paper impregnated with silver nanoparticles for point-of-use water treatment. Environ. Sci. Technol. 45(5):1992-1998.
Crossref

 

Davidson J, Good C, Welsh C, Summerfelt S (2011). The effects of ozone and water exchange rates on water quality and rainbow trout Oncorhynchus mykiss performance in replicated water recirculating systems. Aquacult. Eng. 44(3):80-96.
Crossref

 

Department of Health (DOH) (2009). Independent review of evidence regarding selection of techniques for the suppression of legionella in water supplies of hospitals and other health care premises. 

View

 

Dominique EL, Tydall RL, Mayberry WR, Pancorbo OC (1988). Effects of three oxidizing biocides on Legionella pneumophila serogroup 1. Appl. Environ. Microbiol. 54(3):741-747.

 

Dooling KL, Toews KA, Hicks LA, Garrison LE, Bachaus B, Zansky S, Carpenter LR, Schaffner B, Parker E, Petit S, Thomas A, Thomas S, Mansmann R, Morin C, White B, Langley GE (2015). Active Bacterial Core Surveillance for Legionellosis - United States, 2011-2013. MMWR Morb Mortal Wkly Rep. 64(42):1190-1193.
Crossref

 

Drikas M, Thomson J, Roddick FA (2004). Vacuum ultraviolet irradiation for natural organic matter removal. J. Water Supply Res. Technol. - AQUA 53(4):193-206.

 

Dyksen JE, Spencer C, Khiari D (2016). Study Examines How Disinfection Changes Affect Water Quality.

View

 

Eagleton J (1999). Ozone in Drinking Water Treatment. 

View

 

Edelstein PH, Whittaker RE, Kreiling RL, Howell CL (1982). Efficacy of ozone in eradication of Legionella pneumophila from hospital plumbing fixtures. Appl. Environ. Microbiol. 44(6):1330-1334.

 

Fawell J (2003). Drinking Water Contaminants. British Med. Bull. 68:199-208.
Crossref

 

Franzin L, Cabodi D, Fantino C (2002). Evaluation of the efficacy of ultraviolet irradiation for disinfection of hospital water contaminated by Legionella. J. Hosp. Infect. 51(4):269.
Crossref

 

Frimmel FH (1998). Impact of light on the properties of aquatic natural organic matter. Environ. Int. 24:559-571.
Crossref

 

Gadgil A, Drescher A, Greene D, Miller P, Motau C, Stevens F (1997). Field-testing UV disinfection of drinking water. In WEDC conference: water and sanitation for all, Durban (South Africa). 

View

 

Gadgil A, Greene D, Drescher A, Miller P, Kibata N (1998). Low Cost UV Disinfection System For Developing Countries: Field Tests In South Africa. In First International Symposium on Safe Drinking Water in Small Systems. 

View

 

García M, Baladrón B, Gil V, Tarancon M, Vilasau A, Iba-ez A, Pelaz C (2008). Persistence of chlorine-sensitive Legionella pneumophila in hyperchlorinated installations. J. Appl. Microbiol. 105(3):837-847.
Crossref

 

Gilman RH, Skillicorn P (1985). Boiling of drinking-water: Can a fuel-scarce community afford it? Bull. World Health Organ. 63(1):157-163.

 

Gopal K, Tripathy SS, Bersillon JL, Dubey SP (2007). Chlorination byproducts, their toxicodynamics and removal from drinking water. J. Hazard. Mater. 140(1-2):1-6.
Crossref

 

Gorchev HG, Ozolins G (2011). WHO guidelines for drinking-water quality. WHO Chronicle 38(3):104-108.

 

Groothuis DG, Veenendaal HR, Dijkstra HL (1985). Influence of temperature on the number of Legionella pneumophila in hot water systems. J. Appl. Bacteriol. 59(6):529-536.
Crossref

 

Hall KK, Giannetta ET, Getchell-White SI, Durbin LJ, Farr BM (2003). Ultraviolet light disinfection of hospital water for preventing nosocomial Legionella infection: a 13-year follow-up. Infect. Control Hosp. Epidemiol. 24(8):580-583.
Crossref

 

Hambidge A (2001). Reviewing efficacy of alternative water treatment techniques. Health Estate. 55(6):23-25.

 

Harris GD, Adams VD, Sorensen DL, Curtis MS (1987). Ultraviolet inactivation of selected bacteria and viruses with photoreactivation of the bacteria. Water Res. 21(6):687-692.
Crossref

 

Heuner K, Swanson M (2008). Legionella: Molecular Microbiology. (K. Heuner & M. Swanson, Eds.). Caister Academic Press. 

View

 

Hijnen WAM, Beerendonk EF, Medema GJ (2006). Inactivation credit of UV radiation for viruses, bacteria and protozoan (oo)cysts in water: A review. Water Res. 40(1):3-22.
Crossref

 

Hilbi H, Jarraud S, Hartland E, Buchrieser C (2010). Update on Legionnaires' disease: Pathogenesis, epidemiology, detection and control: MicroMeeting. Mol. Microbiol. 76:1-11.
Crossref

 

Huang HI, Shih HY, Lee CM, Yang TC, Lay JJ, Lin YE (2008). In vitro efficacy of copper and silver ions in eradicating Pseudomonas aeruginosa, Stenotrophomonas maltophilia and Acinetobacter baumannii: Implications for on-site disinfection for hospital infection control. Water Res. 42(1-2):73-80.
Crossref

 

International Federation of Red Cross And Red Crescent Societies (IFRC). (2008). Emergency appeal ; Uganda: Epidemics. 

View

 

Kim BR, Anderson JE, Mueller SA, Gaines WA, Kendall AM (2002a). Disinfection of domestic water systems for Legionella pneumophila. Water Res. 36(18):4433-4444
Crossref

 

Kim BR, Anderson JE, Mueller SA, Gaines WA, Kendall AM (2002b). Literature review - Efficacy of various disinfectants against Legionella in water systems. Water Res. 36(18):4433-4444.
Crossref

 

Konishi T, Yamashiro T, Koide M, Nishizono A (2006). Influence of temperature on growth of Legionella pneumophila biofilm determined by precise temperature gradient incubator. J. Biosci. Bioeng. 101(6):478-484.
Crossref

 

Kruithof JC, Van der Leer RC, Hijnen WAM (1992). Practical experiences with UV disinfection in the Netherlands. J. Water SRT - Aqua 41(2):88-94.

 

Kuchta JM, States SJ, McNamara AM, Wadowsky RM, Yee RB (1983). Susceptibility of Legionella pneumophila to chlorine in tap water. Appl. Environ. Microbiol. 46(5):1134-1139.

 

Kümpers P, Tiede A, Kirschner P, Girke J, Ganser A, Peest D (2008). Legionnaires' disease in immunocompromised patients: A case report of Legionella longbeachae pneumonia and review of the literature. J. Med. Microbiol. 57(3).
Crossref

 

Kusnetsov J, Iivanainen E, Elomaa N, Zacheus O, Martikainen PJ (2001). Copper and silver ions more effective against Legionellae than against mycobacteria in a hospital warm water system. Water Res. 35(17):4217-4225.
Crossref

 

Lenntech (2011). Disinfectants Copper-silver ionization. 

View

 

Lin EY, Stout JE, Yu VL (2011). Controlling Legionella in hospital drinking water: an evidence-based review of disinfection methods. Infect. Control Hosp. Epidemiol. 32(2):166-173.
Crossref

 

Lin SY, Stout JE, Yu VL, Vidic RD (1998). Disinfection of water distribution systems for Legionella. Semin. Respir. Infect. 13(2):147-59.

 

Lin Y, Vidic R (1996). Individual and combined effects of copper and silver ions on inactivation of Legionella pneumophila. Water Res. 30(8):1905-1913.
Crossref

 

Lin YSE, Vidic RD, Stout JE, Yu VL (2002). Negative effect of high pH on biocidal efficacy of copper and silver ions in controlling Legionella pneumophila. Appl. Environ. Microbiol. 68(6):2711-2715.
Crossref

 

Liu Z, Stout JE, Tedesco L, Boldin M, Hwang C, Yu VL (1995). Efficacy of ultraviolet light in preventing Legionella colonization of a hospital water distribution system. Water Res. 29(10):2275-2280.
Crossref

 

Luby SE, Syed AH, Atiullah N, Faizan MK, Fisher-Hoch S (2000). Limited effectiveness of home drinking water purification efforts in Karachi, Pakistan. Int. J. Infect. Dis. 4(1):3-7.
Crossref

 

Marchesi I, Marchegiano P, Bargellini A, Cencetti S, Frezza G, Miselli M, Borella P (2011). Effectiveness of different methods to control legionella in the water supply: ten-year experience in an Italian university hospital. J. Hosp. Infect. 77(1):47-51.
Crossref

 

Marin P (2009). Public Private Partnerships for Urban Water Utilities: A Review of developing countries. 
Crossref

 

Mcdonnell G, Russell AD, Block SS (1999). Disinfection, sterilization, and preservation. Clin. Microbiol. Rev. 12:147-179

 

Meunier L, Canonica S, von Gunten U (2006). Implications of sequential use of UV and ozone for drinking water quality. Water Res. 40(9):1864-1876.
Crossref

 

Miller R (2008). Preventing Legionella: Common Disinfection Techniques. 

 

Mintz ED, Bartram J, Lochery P, Wegelin M (2001). Not just a drop in the bucket: Expanding access to point-of-use water treatment systems. Am. J. Public Health 91(10):1565-1570.
Crossref

 

Mòdol J, Sabrià M, Reynaga E, Pedro-Botet ML, Sopena N, Tudela P, Rey-Joly C (2007). Hospital-acquired legionnaires disease in a university hospital: impact of the copper-silver ionization system. Clin. Infect. Dis. Official Pub. Infect. Dis. Soc. Am. 44:263-265.
Crossref

 

Morrison S, Venter A, Barnard S (2012). A case study to determine the efficacy of ozonation in purification processes. Water SA 38(1).
Crossref

 

Mosler HJ, Kraemer SM, Johnston RB (2013). Achieving long-term use of solar water disinfection in Zimbabwe. Public Health 127(1):92-98.
Crossref

 

Mouchtouri V, Velonakis E, Hadjichristodoulou C (2007). Thermal disinfection of hotels, hospitals, and athletic venues hot water distribution systems contaminated by Legionella species. Am. J. Infect. Control 35(9):623-627.
Crossref

 

Muraca P, Stout JE, Yu VL (1987). Comparative assessment of chlorine, heat, ozone, and UV light for killing Legionella pneumophila within a model plumbing system. Appl. Environ. Microbiol. 53(2):447-453.

 

Muraca PW, Yu VL, Goetz A (1990). Disinfection of water distribution systems for legionella: a review of application procedures and methodologies. Infect. Control Hosp. Epidemiol. 11(2):79-88.
Crossref

 

Murinda S, Kraemer S (2008). The potential of solar water disinfection as a household water treatment method in peri-urban Zimbabwe. Phys. Chem. Earth Parts A/B/C 33(8-13):829-832.
Crossref

 

National Research Council (US) Safe Drinking Water Committee. (NRC) (1980). The Disinfection of Drinking Water. National Academies Press (US), 2. 

View

 

Oguma K, Katayama H, Ohgaki S (2004). Photoreactivation of Legionella pneumophila after inactivation by low- or medium-pressure ultraviolet lamp. Water Res. 38(11):2757-2763.
Crossref

 

Oppenheimer JAJ, Jacangelo JJG, La JM, Hoagland JE (1997). Testing the equivalency of ultraviolet light and chlorine for disinfection of wastewater to reclamation standards. Water Environ. 69(1):14-24.
Crossref

 

Orsi GB, Vitali M, Marinelli L, Ciorba V, Tufi D, Del Cimmuto A, De Giusti M (2014). Legionella control in the water system of antiquated hospital buildings by shock and continuous hyperchlorination: 5 years experience. BMC Infect. Dis. 14(1):394.
Crossref

 
 

Parikka M (2004). Global biomass fuel resources. Biomass Bioenergy 27(6):613-620.
Crossref

 
 

Parry MF, Stampleman L, Hutchinson JH, Folta D, Steinberg MG, Krasnogor LJ (1985). Waterborne Legionella bozemanii and Nosocomial pneumonia in immunosuppressed patients. Ann. Internal Med. 103(2):205-210.
Crossref

 
 

Peiró Callizo EF, Sierra JD, Pombo JM, Baquedano CE, Huerta PB (2005). Evaluation of the effectiveness of the Pastormaster method for disinfection of legionella in a hospital water distribution system. J. Hosp. Infect. 60(2):150-8.
Crossref

 
 

Peletz R, Mahin T (2009). Effectiveness of different household water treatment approaches for people living with HIV/AIDS in Africa. In Proceedings of the 34th WEDC Conference in Addis Ababa, Ethiopia, 34. Leicestershire: Water, Engineering and Development Centre (WEDC). 

View

 
 

Plouffe JF, Webster LR, Hackman B (1983). Relationship between colonization of hospital building with Legionella pneumophila and hot water temperatures. Appl. Environ. Microbiol. 46:769-770.

 
 

Rajagopaul R , Mbongwa NW, Nadan C (2008). Guidelines For The Selection And Effective Use Of Ozone In Water Treatment. 

View

 
 

Rangel FM, Rhomberg P, Hollis RJ, Pfaller MA, Wenzel RP, Helms CM, Herwaldt LA (1999). Persistence of Legionella pneumophila in a hospital's water system: a 13-year survey. Infect. Control Hosp. Epidemiol. 20(12):793-797.
Crossref

 
 

Rencken GE (1994). Ozonation at wiggins-water-purification-works, durban, south-africa. Ozone-Sci. Eng. 16(3):247-260.
Crossref

 
 

Ricketts KD, Joseph CA (2005). Legionnaires' disease in Europe 2003-2004. Euro Surveillance : Bulletin Europ??en Sur Les Maladies Transmissibles. Eur. Commun. Dis. Bull. 10(12):256-259.

 
 

Rogers J, Dowsett A, Dennis P, Lee J, Keevil C (1994). Influence of Temperature and Plumbing Material Selection on Biofilm Formation and Growth of Legionella-Pneumophila in a Model Potable Water-System Containing Complex Microbial-Flora. Appl. Environ. Microbiol. 60(5):1585-1592.

 
 

Rohr U, Senger M, Selenka F, Turley R, Wilhelm M (1999). Four years of experience with silver-copper ionization for control of legionella in a german university hospital hot water plumbing system. Clin. Infect. Dis. Official Pub. Infect. Dis. Soc. Am. 29(6):1507-1511.
Crossref

 
 

Rosa G, Clasen T (2010). Estimating the scope of household water treatment in low- and medium-income countries. Am. J. Trop. Med. Hygiene 82(2):289-300.
Crossref

 
 

Rowbotham TJ (1980). Preliminary report on the pathogenicity of Legionella pneumophila for freshwater and soil amoebae. J. Clin. Pathol. 33(12):1179-1183.
Crossref

 
 

Said MBEN, Otaki M (2013). Enhancement of ultraviolet water disinfection process. Afr. J. Biotechnol. 12(20):2932-2938.

 
 

Schoenen D (2002). Role of disinfection in suppressing the spread of pathogens with drinking water: Possibilities and limitations. Water Res. 36(15):3874-3888.
Crossref

 
 

Schulze-Robbecke R, Buchholtz K (1992). Heat susceptibility of aquatic mycobacteria. Appl. Environ. Microbiol. 58(6):1869-1873.

 
 

States S, Kuchta J, Young W, Conley L, Ge J, Costello M, Wadowsky R (1998). Controlling Legionella using copper-silver ionization. J. Am. Water Works Assoc. 90(9):122-129.

 
 

Steinert M, Ockert G, Luck C, Hacker J (1998). Regrowth of Legionella pneumophila in a heat-disinfected plumbing system. Zentralbl Bakteriol. 288(3):331-342.
Crossref

 
 

Stout JE, Best MG, Yu VL (1986). Susceptibility of members of the family Legionellaceae to thermal stress: implications for heat eradication methods in water distribution systems. Appl. Environ. Microbiol. 52(2):396-399.

 
 

Stout JE, Yu VL (2003). Experiences of the first 16 hospitals using copper-silver ionization for Legionella control: implications for the evaluation of other disinfection modalities. Infection Control and Hospital Epidemiology. Official J. Soc. Hosp. Epidemiol. Am. 24(8):563-568.

 
 

Summerfelt ST (2003). Ozonation and UV irradiation - An introduction and examples of current applications. Aquacult. Eng. 28:21-36.
Crossref

 
 

Swanson M, Hammer B (2000). Legionella Pneumophila Pathogenesis: A Fateful Journey from Amoebae to Macrophages. Annu. Rev. Microbiol. 54:567-613.
Crossref

 
 

TARN-PURE Ltd. (2016). Water-borne Disease Information for Health & Safety Executives. 

View

 
 

Tobin JO, Swann RA, Bartlett CL (1981). Isolation of Legionella pneumophila from water systems: methods and preliminary results. Br. Med. J. (Clinical Res. Ed.) 282(6263):515-517.
Crossref

 
 

United Nations Children's Emergency Fund (UNICEF) (2011). Situation Report - Horn of Africa Crisis Kenya. 

View

 
 

United Nations Department of Economics and Social Affairs (UNDESA) (2014). International Decade for action " Water for Life" 2005-2015. 

View

 
 

United States Environmental Protection Agency (USEPA) (2001). Legionella: Drinking Water Health Advisory. 

View

 
 

Dynamics UV (2016). UV Water Disinfection FAQ. 

View

 
 

Van der Merwe W, Beukes J, Van Zyl P (2012). Cr(VI) formation during ozonation of Cr-containing materials in aqueous suspension – implications for water treatment. Water SA 38(4).
Crossref

 
 

Varkey A (2010). Antibacterial properties of some metals and alloys in combating coliforms in contaminated water. Sci. Res. Essays 5(24):3834-3839.

 
 

Varkey AJ, Dlamini D (2012). Point-of-use water purifcation using clay pot water flters and copper mesh. Water SA 38(5):721-726.
Crossref

 
 

Von Gunten U (2003). Ozonation of drinking water: Part II. Disinfection and by-product formation in presence of bromide, iodide or chlorine. Water Res. 37(7):1469-1487.
Crossref

 
 

Wajon JE, Kavanagh BV, Kagi RI, Rosich RS, Alexander R (1988). Controlling swampy odors in drinking water. J. Am. Water Works Assoc. 80(6):77-83.

 
 

Walfer M (2013). Water purification. 

View

 
 

Wei C, Zhang F, Hu Y, Feng C, Wu H (2016). Ozonation in water treatment: the generation, basic properties of ozone and its practical application. Rev. Chem. Eng. 0167(8299):2191-0235.

 
 

Whitacre DM (2010). Reviews of Environmental Contamination and Toxicology. Rev. Environ. Contamin. Toxicol. P 202.
Crossref

 
 

World Health Organization (WHO). (2007). LEGIONELLA and the prevention of legionellosis. 

View

 
 

Wright HB, Cairns WL (1998). Ultra Violet Light. 

View

 
 

Zheng Y, Dunets S, Cayanan D (2012). COPPER-Silver IONIZATION. Greenhouse and Nusery Water Treatment Information. 

View