Journal of
AIDS and HIV Research

  • Abbreviation: J. AIDS HIV Res.
  • Language: English
  • ISSN: 2141-2359
  • DOI: 10.5897/JAHR
  • Start Year: 2009
  • Published Articles: 297

Full Length Research Paper

Immunological and clinical assessment of adult HIV patients following switch to second-line antiretroviral regimen in a large HIV Program in North-central Nigeria

Stephen Boerwhoen Dapiap
  • Stephen Boerwhoen Dapiap
  • Department of Strategic information, Institute of Human Virology, Abuja, FCT, Nigeria.
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Babatunde Adeshina Adelekan*
  • Babatunde Adeshina Adelekan*
  • Department of Strategic information, Institute of Human Virology, Abuja, FCT, Nigeria.
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Nicaise Ndembi
  • Nicaise Ndembi
  • Department of Laboratory Research and Implementation Science, Institute of Human Virology, Abuja, FCT, Nigeria.
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Fati Murtala-Ibrahim
  • Fati Murtala-Ibrahim
  • Department of Strategic information, Institute of Human Virology, Abuja, FCT, Nigeria.
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Patrick Sunday Dakum
  • Patrick Sunday Dakum
  • Department of Clinical Medicine, Institute of Human Virology, Abuja, FCT, Nigeria.
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Ahmad Tijjani Aliyu
  • Ahmad Tijjani Aliyu
  • Department of Strategic information, Institute of Human Virology, Abuja, FCT, Nigeria.
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  •  Received: 31 January 2017
  •  Accepted: 28 February 2017
  •  Published: 31 May 2017


Addisu A, Dagim A, Tadele E, Adissu A, Mussie A, Filmon K (2015) . CD4 Cell Count Trends after Commencement of Antiretroviral Therapy among HIV-Infected Patients in Tigray, Northern Ethiopia: A Retrospective Cross-Sectional Study. PLoS One 10(3):1-9 e0122583.


Antinori A, Coenen T, Costagiola D, Dedes N, Ellefson M, Gatell J, Girardi E, Johnson M, Kirk O, Lundgren J, Mocroft A, D'Arminio Monforte A, Phillips A, Raben D, Rockstroh JK, Sabin C, Sönnerborg A, De Wolf F (2011). Late presentation of HIV infection: a consensus definition. HIV Med.12:61-64.


Attia A, Huët C, Anglaret X, Toure S, Ouassa T, Gourvellec G, Menan H, Dakoury-Dogbo N, Combe P, Chêne G, N'Dri-Yoman T, Salamon R (2001). HIV-1-related morbidity in adults, Abidjan, Cote d'Ivoire: a nidus for bacterial diseases. J. Acquir. Immune Defic. Syndr. 28:478-486.


Boulle A, Van Cutsem G, Hilderbrand K, Cragg C, Abrahams M, Mathee S, Ford N, Knight L, Osler M, Myers J, Goemaere E, Coetzee D, Maartens G (2010). Seven-year experience of a primary care antiretroviral treatment programme in Khayelitsha, South African. AIDS 24:563-572.


Chioma O, Vincent U, Samuel Oyadongha (2012). World Aids Day: Nigeria records decline in new HIV infections. 


Ford N, Roberts T, Calmy A (2012). Viral load monitoring in resource-limited settings: a medical and public health priority. AIDS 26(13):1719-1720.


Geng EH, Hunt PW, Diero LO, Kimaiyo S, Somi GR, Okong P, Bangsberg DR, Bwana MB, Cohen CR, Otieno JA, Wabwire D, Elul B, Nash D, Easterbrook PJ, Braitstein P, Musick BS, Martin JN, Yiannoutsos CT, Wools-Kaloustian K (2011). Trends in the clinical characteristics of HIV-infected patients initiating antiretroviral therapy in Kenya, Uganda and Tanzania between 2002 and 2009. J. Int. AIDS Soc. 14:46.


Gilks CF, Crowley S, Ekpini R, Gove S, Perriens J, Souteyrand Y, Sutherland D, Vitoria M, Guerma T, De Cock K (2006) . The WHO public-health approach to antiretroviral treatment against HIV in resource-limited settings. Lancet 368(9534):505-510.


Kelley CF, Kitchen CM, Hunt PW, Rodriguez B, Hecht FM, Kitahata M, Crane HM, Willig J, Mugavero M, Saag M, Martin JN, Deeks SG (2009). Incomplete Peripheral CD4+ Cell Count Restoration in HIV-Infected patients Receiving Long-Term Antiretroviral Treatment. Clin. Infect. Dis. 48:787-794.


Kyaw NL, Thanachartwet V, Kiertiburanakul S, Desakorn V, Chamnanchanunt S, Chierakul W, Manosuthi W, Pitisuttithum P, Sungkanuparph S (2013). Baseline CD4 cell counts and outcomes among adult treatment naïve HIV patients after taking fixed dose combination GBO-VIR-S and GBO-VIR-Z in Thailand, Southeast Asian J. Trop. Med. Public Health 44:232-243.


Lawn SD, Myer L, Bekker L, Wood R (2006). CD4 cell count recovery among HIV-infected patients with very advanced immunodeficiency commencing antiretroviral treatment in sub-Sahara Africa. BMC infect. Dis. 6:59.


Marshall CS, Curtis A, Spelman T, O'Brien DP, Greig J, Shanks L, du Cros P, Casas EC, da Fonseca MS, Athan E, Elliott JH (2013). Impact of HIV-associated conditions on mortality in people commencing antiretroviral therapy in resource limited settings. PLoS One 8:e68445.


Nathan F, Marco V, Gottfried H, Meg D (2013). Getting to zero HIV deaths: progress, challenges and ways forward. J. Int. AIDS Soc. 16:18927.


National AIDS & STI Control Programme (NASCP) (2014). 2014 Annual report on HIV/AIDS Health Sector response in Nigeria. Federal Ministry of Health.


PAGAA (Panel on Antiretroviral Guidelines for Adults and Adolescents) (2015) .Guidelines for the use of Antiretroviral agents in HIV1 infected


Renauld-Thery F, Nguimfack BD, Vitoria M, Lee E, Graaff P, Samb B, Perriëns J (2007). Use of antiretroviral therapy in resource-limited countries in 2006: distribution and uptake of first- and second-line regimens. AIDS 21(Suppl)4:S89-95.


Smith CJ, Sabin CA, Youle MS, Loes SK, Lampe FC, Madge S, Cropley I, Johnson MA, Phillips AN (2004). Factors influencing increases in CD4 cell counts of HIV positive persons receiving long-term highly active antiretroviral therapy. J. Infect. Dis. 190:1860-1868.


WHO (World Health Organisation) (2013). Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. Recommendations for a public health approach. 


WHO (World Health Organisation) (2016). Prevent HIV, Test and Treat All. WHO Support for Country Impact. 


Zeitz PS (2017). President's Emergency Plan for AIDS Relief's (PEPFAR) Use of Geospatial Data. U.N. World Data Forum.