Different solvent extract of Passiflora incarnata (L.), known for antibacterial activity, were investigated for antibacterial efficacy against Staphylococcus aureus (oxacillin resistance strain) and Escherichia coli by disc diffusion method. The secondary metabolites extracted in methanolic extract were found to be more potent as compared to ethyl acetate, as it shows Minimal Inhibitory Concentration (MIC) at extreme lower dilutions. Thin Layer Chromatography (TLC)-bioautography indicated Passicol as a major active compound in ethyl acetate and flavonoid in methanol extract.
Key words: Passiflora incarnata (L.), passicol, secondary metabolites, antibacterial activity.
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