Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3830

Full Length Research Paper

Antimicrobial activity against periodontopathic bacteria and cytotoxic study of Cratoxylum formosum and Clausena lansium

Jintakorn Kuvatanasuchati1, Surat Laphookhieo2 and Pirasut Rodanant3*
1Department of Microbiology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand. 2Natural Products Research Laboratory, School of Science, Mae Fah Luang University, Chieng Rai, Thailand. 3Department of Advanced General Dentistry, Faculty of Dentistry, Mahidol University, Bangkok, Thailand.
Email: [email protected]

  •  Accepted: 21 September 2011
  •  Published: 09 November 2011

Abstract

Cratoxylum formosum ssp. pruniflorum and Clausena lansium are among edible plants that commonly used for various ethnomedical conditions. This study investigated antimicrobial activity against periodontopathic bacteria using agar diffusion technique. These plant extracts demonstrated comparable antimicrobial efficacy against black-pigmented bacteria strains to standard drug chlorhexidine. The CD50 of C. formosum and C. lansium on HGF cells were 0.37 and 0.16 mg/ml, respectively, demonstrated using the MTT assay.

 

Key words: Antimicrobial activity, cytotoxic activity, Cratoxylum formosum ssp. pruniflorum,Clausena lansium.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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