Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3832

Full Length Research Paper

Antioxidant activity and total phenolic content of medicinal plants associated with prevention and treatment of cardiovascular and cerebrovascular diseases

Ren-You Gan1, Xiang-Rong Xu2, Feng-Lin Song1, Lei Kuang1 and Hua-Bin Li1*
1Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China. 2Key Laboratory of Marine Bio-resources Sustainable Utilization, South China Sea Institute of Oceanology, Chinese Academy of Sciences, Guangzhou 510301, China.
Email: [email protected]

  •  Accepted: 18 October 2010
  •  Published: 18 November 2010

Abstract

In order to find new resources of natural antioxidants, antioxidant activities of 40 medicinal plants associated with prevention and treatment of cardiovascular and cerebrovascular diseases were evaluated using ferric reducing antioxidant power (FRAP) and Trolox equivalent antioxidant capacity (TEAC) assays, respectively, and their total phenolic contents were measured by the Folin-Ciocalteu method. Most of these plants were analyzed for the first time for their antioxidant activities. Generally, these plants had high antioxidant capacities and total phenolic contents. A significant correlation between the FRAP value and the TEAC value suggested that antioxidant components in these plants were capable of reducing oxidants and scavenging free radicals. A high correlation between antioxidant capacity and total phenolic content indicated that phenolic compounds could be the main contributor of the antioxidant activity of these plants. Several plants, such as Sanguisorba offivinalisRosa chinensis,Millettia dielsianaPolygonum cuspidatumCaesalpinia sappan and Sophora japonica,showed the highest antioxidant activities and total phenolic contents. These plants could be potential rich resources of natural antioxidants and could be developed into functional food or drug for prevention and treatment of diseases caused by oxidative stress.

 

Key words: Plant, antioxidant activity, phenolic content.