Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3834

Table of Content: 18 November 2010; 4(22)

November 2010

Hoodia gordonii in the treatment of obesity: A review

According to data from the World Health Organization (WHO), one billion adults that are approximately overweight currently exist in the world, of which three hundred million are obese. These numbers led to the finding that obesity appears as a major global epidemic, affecting countries in all stages of development. In Brazil, about 13% of the population is now considered obese and estimates suggest that by the year...

Author(s): Chrystian Araújo Pereira, Luciana Lopes Silva Pereira and Angelita Duarte Corrêa

November 2010

Antimicrobial and free radical scavenging activity of extracts of some Indian medicinal plants

Antimicrobial and antioxidant potency of aqueous and organic solvent extracts of five Indian medicinal plants (Prosopis cineraria, Capparis decidua, Tinospora cordifolia, Carissa carandas and Cordia dichotoma) was investigated. The acetone and ethanol extracts exhibited highest antimicrobial activity (60 to 80% and 40 to 60%, respectively) againstStaphylococcus aureus, Staphylococcus...

Author(s): Raj Kumar Salar and Anjali Dhall

November 2010

Phytochemical screening and antibacterial activity of Citrullus colocynthis (Linn.) Schrad against Staphylococcus aureus

Citrullus colocynthis (Linn.) Schrad (CCT) is an important medicinal plant belonging to the family of Cucurbitaceae. It is a well recognized plant in the traditional medicine and was used by people in rural areas as a purgative, antidiabetic and insecticide. In the present investigation, after phytochemical screening of CCT through standard experimental procedure, antibacterial...

Author(s): Shahla Najafi, Nima Sanadgol, Batool Sadeghi Nejad, Maryam Ashofteh Beiragi and Ehsan Sanadgol

November 2010

The effects of grape seed and grape pomace extracts on spatial memory impairment induced by hyoscine in mice

The cholinergic system and its receptors play a role in memory function. Hyoscine, as an anticholinergic agent causes dysfunction to the spatial memory and learning. The present study aims to evaluate the effects of two different extracts of grape seed (25, 50, 75 mg/kg) and grape pomace (25, 50,100 mg/kg) on the spatial memory impairment induced by hyoscine (1 mg/kg) in male mice. Spatial memory was evaluated using...

Author(s): Akram Jamshidzadeh, Batool Faeghe Baha-al-dini Baigi and Mehrdad Aram

November 2010

Immunosuppressive effects of Cucurbitacin B on human peripheral blood lymphocytes

This study investigates the immunomodulating effects of cucurbitacin B, a Thai herbal plant; isolated from Trichosanthes cucumerima L., on PHA-stimulated human Peripheral Blood Mononuclear Cells (PBMCs). Stimulated PBMCs were cultured in the presence or absence of cucurbitacin B and then markers of cell activation were measured. The results showed that 0.5 and 0.25 µg/ml of cucurbitacin B...

Author(s): Yaowalak U-pratya, Usaneeporn Lueangamornnara, Weena Jiratchariyakuland Tanawan Kummalue

November 2010

Efficacy of ethanolic leaf extracts of Carica papaya and Terminalia catappa as molluscicides against the snail intermediate hosts of schistosomiasis

The study evaluated the molluscicidal effects of ethanolic leaf extracts of two Nigerian indigenous medicinal plants; Terminalia catappa and Carica papaya. Different concentrations 2500, 630, 160, 40 and 10 ppm were prepared from the stock solution of the extracts. AdultBiomphalaria pfeifferi and Bulinus globosus were exposed to these different graded concentrations. Mortalities were...

Author(s): Adetunji, V. O. and Salawu, O. T.

November 2010

The effect of pruning on growth and chemical composition of cultivated bush tea (Athrixia phylicoides D.C)

A trial to determine the effect of pruning at different heights on growth and quality of cultivated bush tea was conducted. Pruning of bush tea largely led to crop losses. Unpruned bush tea plants remained the tallest plants, with higher number of branches, bigger leaf area and a larger biomass than apically pruned, middle pruned and base pruned bush tea plants. Pruning at different heights also proved to have little or...

Author(s): M. Maudu, F. N. Mudau and I. K. Mariga

November 2010

Protective effect of garlic oil against liver injury in experimental animals

Food derived antioxidants have a strong potential effect on the long term as chemopreventive agents in disease states involving oxidative stress, such as hepatitis. This study was done to clarify the potential effect of garlic oil in protecting the liver from lipopolysaccharide-induced hepatitis in D-galactosamine sensitized rats. Sixty male albino rats were used in the study. They were divided into four groups (15 rats...

Author(s): Zakaria El-Khayat, Wafaa Rasheed, Tahany Ramzy, Jihan Hussein, Mervat Agaiby, Safaa Morsy, Fatma Morsy and Nermeen Shaffie

November 2010

Inhibition of nitric oxide production and mRNA expressions of proinflammatory mediators by xylarinic acid A in RAW 264.7 cells

Mushrooms possess vast and yet unknown source of powerful new pharmaceutical products, which contain active biomolecules. Xylarinic acid A isolated from a mushroom,Xylaria polymorpha, has been reported to have free radicals scavenging property and anti-fungal activity. However, information of its anti-inflammatory activity is scarce. Therefore, the objective of this study was to examine the effect of the compound...

Author(s): Chang Geon Kim, Tae-Wan Kim, Mehari Endale, Taddesse Yayeh, Gon-Sik Seo, Jae Yeul Cho, Hwa-Jin Park, Sang-Keun Kim, In-Kyoung Lee, Bong-Sik Yunand Man Hee Rhee

November 2010

In vitro antiviral activity of diterpenes isolated from the Brazilian brown alga Canistrocarpus cervicornis

They describe in this paper that the dolastane diterpenes 4-hydroxy-9,14-dihydroxydolasta-1(15),7-diene (1) and 4,7,14-trihydroxydolasta-1(15),8-diene (2), isolated from the marine brown alga Canistrocarpus cervicornis inhibited HSV-1 infection in Vero cells. The concentration required to inhibit HSV-1 replication was not cytotoxic. Their results suggest that the structures of diterpenes 1 and 2, dolastane...

Author(s): Magui Aparecida Vallim, Juliana Eymara Barbosa, Diana Negrão Cavalcanti, Joel Campos De-Paula, Viveca Antonia Giongo Galvão da Silva, Valéria Laneuville Teixeira and Izabel Christina Nunes de Palmer Paixão,

November 2010

Cytotoxicity activity of root extract/fractions of Eurycoma longifolia Jack root against vero and Hs27cells

One extract (TACME) and four fractions (TAF 273, TAF 355, TAF 191 and TAF 401) fromEurycoma longifolia root reported in literature as antimalarial agent were evaluated for their in vitro cytotoxicity activity against two mammalian cell lines (Vero/HS27) which will be use as host for our future antiparasitic activity study. The in vitro cytotoxicity activity was measured by methyl thiazolyl...

Author(s): Nowroji Kavitha, Rahmah Noordin, Kit-Lam Chan and Sreenivasan Sasidharan

November 2010

Quercetin and epigallocatechin gallate in vitro induced changes in the membrane anisotropy of peripheral blood mononuclear cells from patients with inflammatory diseases

The aim of the study was to assess the in vitro effect of quercetin and epigallocatechin gallate on the membrane fluidity of mononuclear blood cells isolated from patients with an inflammatory profile (chronic hyperglycemia and rheumatoid arthritis). The measurements were performed via the evaluation of the fluorescence anisotropy for cells labeled with TMA-DPH. Chronic hyperglycemia does not impair the...

Author(s): Denisa Margina, Mihaela Ilie, Carolina Negrei, Daniela Gradinaru, Andra Balanescu and Niculina Mitrea

November 2010

Comparative antimicrobial activities of Neem, Amla, Aloe, Assam Tea and Clove extracts against Vibrio cholerae, Staphylococcus aureus and Pseudomonas aeruginosa

This study was undertaken to identify medicinal plants that are effective against multiple human pathogens and to partially purify the active component through thin layer chromatography. Antibacterial activity of selected plant extracts were assayed by agar cup diffusion. Minimum inhibitory concentrations were determined against all the pathogens. Sensitivity of the pathogens was also checked with four standard...

Author(s): Shubhi Mehrotra, Ashwani K. Srivastava and Shoma Paul Nandi

November 2010

In vitro regeneration of plantlets from internodal callus culture of Vitex leucoxylon L. – A rare medicinal plant

Attempt was made to standardize the regeneration protocol. Medium was optimized for callusing, organogenesis and rooting of Vitex leucoxylon. Compact and greenish callus from internodal segments was achieved when stem segments were cultured on Murashige and Skoog (MS) medium fortified with 5.37 µM NAA + 2.22 µM BAP. In vitro regeneration of shoot buds was achieved from internodal...

Author(s): M. Amarchand Chordia, R. Sangeetha Kumariand R. Ramesh Kannan

November 2010

Biological screening of the aerial parts of the Sarcococca saligna

The crude methanolic extract of the aerial parts of Sarcococca saligna (Ss.Cr) and its various fractions were screened in vitro for possible antibacterial, antifungal, phytotoxic, haemagglutination and insecticidal activities. The chloroform (CHCl3) fraction and Ss.Cr showed significant (80.76%) and good (76.92%) antibacterial activity against Staphylococcus aureus, respectively, while rest...

Author(s): Bashir Ahmad, Sadia, Sadiq Azam, Shumaila Bashir and Ibrar khan

November 2010

Anticancerous potentials of Achillea species against selected cell lines

Cancer, heart failure and stroke are among the majority frequent causes of death worldwide. Cancer is the second most common reason of death following the cardiovascular diseases. In current  study, two Iranian species of Achillea species as Achillea millefolium and Achillea biebersteinii have been collected from East Azerbaijan of Iran and assayed on six cancerous cell lines; AGS...

Author(s): Ghazaleh Ghavami, Soroush Sardari and Mohammad Ali Shokrgozar

November 2010

Protective effect of Murraya koenigii (L) leaves extract in streptozotocin induced diabetics rats involving possible antioxidant mechanism

Diabetes causes increased oxidative stress, which is thought to play an important role in the pathogenesis of various diabetic complications. The antioxidant actions are keys to preventing or reversing diabetes and its complications. Thus the aim of the present study was to evaluate the antioxidant potential of ethanolic Murraya koenigii leaves (MKL) extract on Thiobarbituric Acid Reactive Substances (TBARS)...

Author(s): S. V. Tembhurne and D. M. Sakarkar

November 2010

Thymus kotschyanus and Carum copticum essential oils as botanical preservatives for table grape

In the present study, essential oils extracted from Thymus kotschyanus and Carum copticumhas been evaluated for efficacy in the control of postharvest fungal decay in Thompson seedless table grape. Results showed that the tested oils exhibited good inhibitory activity against fungal decay in oil-treated grapes. In addition, the essential did not show a negative impact on the sensory quality of...

Author(s): Rasul Jalili Marandi, Abbas Hassani, Youbert Ghosta, Ali Abdollahi, Alireza Pirzad, and Fatemeh Sefidkon

November 2010

Phenolic content, antioxidant capacity, radical oxygen species scavenging and lipid peroxidation inhibiting activities of extracts of five black chokeberry (Aronia melanocarpa (Michx.) Elliot) cultivars

Black chokeberries (Aronia melanocarpa (Michx.) Elliot) are species, the fruit of which are considered to be one of the most valuable sources of phenolic substances and the research in the field of the fruit utilization as a food supplement is more than topical. Nevertheless, as far as this species is concerned, in particular cultivars there are differences which are caused by both their origin and genetic...

Author(s): Otakar Rop, Jiri Mlcek, Tunde Jurikova, Magdalena Valsikova, Jiri Sochor, Vojtech Reznicek and Daniela Kramarova

November 2010

Antioxidant activity and total phenolic content of medicinal plants associated with prevention and treatment of cardiovascular and cerebrovascular diseases

In order to find new resources of natural antioxidants, antioxidant activities of 40 medicinal plants associated with prevention and treatment of cardiovascular and cerebrovascular diseases were evaluated using ferric reducing antioxidant power (FRAP) and Trolox equivalent antioxidant capacity (TEAC) assays, respectively, and their total phenolic contents were measured by the Folin-Ciocalteu method. Most of these plants...

Author(s): Ren-You Gan, Xiang-Rong Xu, Feng-Lin Song, Lei Kuang and Hua-Bin Li

November 2010

Glucose-lowering effect of xoconostle (Opuntia joconostle A. Web., Cactaceae) in diabetic rats

The anti-diabetic effect traditionally attributed to the mesocarpium and cladode of Opuntia joconostle was assessed experimentally in male wistar rats with streptozotocin-induced diabetes (40 mg/kg bodyweight). Groups of six diabetic and six healthy rats were dosed with either water or aqueous extracts of mesocarpium, cladode or a 50:50 mixture of both. The dose, defined through a screening experiment, was 100...

Author(s): Rúbia Cassiana Paiz, Bertha Irene Juárez-Flores, Juan Rogelio Aguirre Rivera Norma Cecilia Cárdenas Ortega, Juan Antonio Reyes Agüero, Erika García Chávez and Gregorio Álvarez Fuentes