Abstract

There is resurgent interest in exploring the anti-platelet activity of medicinal plant extracts because these are cost effective, easily available form of indigenous resources and are comparable to synthetic blood thinners in this prospective. Current investigation has been carried out to assess the anti-platelet activity of crude methanolic extracts of Grewia asiatica L. leaves and Terminalia chebula Retz. fruits. Both crude extracts exhibited potent platelet aggregation inhibition activity in a dose-dependent manner at concentration range (1 to 10 mg/ml). This preliminary screening suggests that G. asiatica L. leaves and T. chebulaRetz fruits crude extract can be considered as herbal treatment for disease associated with blood clotting.

Key words: Anti-platelet activity, Grewia asiatica L., Terminalia chebula Retz.