Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3778

Review

Phytochemical constituents and bioactivities of the extracts of Cassia nigricans Vahl: A review

R. G. Ayo
Samaru College of Agriculture, Ahmadu Bello University, Zaria, Nigeria.
Email: [email protected]

  •  Accepted: 16 June 2010
  •  Published: 30 July 2010

Abstract

Cassia species have been of keen interest in phytochemical and pharmacological research due to their excellent medicinal values. They are rich sources of polyphenols, anthraquinone derivatives, flavonoids and polysaccharides. Cassia nigricans Vahl is an important source of secondary metabolites, notably anthraquinone derivatives. The leaves of C. nigricans Vahl have been reported to contain pharmacologically active substances, including 1,6,8-trihydroxy-3-methyl anthraquinone (emodin), emodic acid, citreorosein, a flavonoid - luteolin, and hydroxyestranic acid, ethyl ester. C. nigricans Vahl is of high therapeutic value in gastro-intestinal disorders, including ulcers and diarrhoea, and skin diseases. It possesses antimicrobial, antiulcer, analgesic, anti-inflammatory, contraceptive, antiplasmodial, insecticidal and larvicidal activities. The plant has the potential to be used in the management of agricultural pests. In conclusion, C. nigricans Vahlcontains biologically active compounds that may serve as candidates for new drugs in the treatment and prevention of human and livestock diseases, and pest management.

 

Key words: Cassia nigricans Vahl, ethnomedicine, chemical constituents, anthraquinones, bioactivities.