Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835


Toxicology of Dysosma versipallis rhizome: A review

Man Liang1, Yan Liu1, Sunnassee Ananda1, Luo Zhuo1 and Liang Liu2*
1Department of Forensic Medicine, Tongji Medical College, Huazhong University of Science and Technology, 430030, Wuhan, People’s Republic of China. 2Key Laboratory of Evidence Science (China University of Political Science and Law), Ministry of Education, 100040, Beijing, China.
Email: [email protected]

  •  Accepted: 07 April 2010
  •  Published: 04 May 2010


According to the World Health Organization and the National Institutes of Health, Traditional Chinese medicine originated more than 3000 years ago. While there are quite obvious medical values suggesting that Dysosma versipallis rhizome is both desirable and achievable, there are still obstacles. Since the therapeutic dose and toxic dose are very close, D. versipallis rhizome poisoning cases were frequently reported. In this paper, the plant source, chemical constituent, toxicity reason, toxic dose, mechanism of toxicity, poisoning symptoms, pathological changes of body tissues after ingestion of D. versipallis rhizome poisoning and medical management are reviewed.


Key words: Dysosma versipallis rhizome, podophyllotoxin, toxicology, review.