May 2010
Toxicology of Dysosma versipallis rhizome: A review
According to the World Health Organization and the National Institutes of Health, Traditional Chinese medicine originated more than 3000 years ago. While there are quite obvious medical values suggesting that Dysosma versipallis rhizome is both desirable and achievable, there are still obstacles. Since the therapeutic dose and toxic dose are very close, D. versipallis rhizome poisoning...
May 2010
Evaluation of analgesic and anti-inflammatory activities of n-butanol phase of the leaves extract of Microtrichia perotitii DC (Asteraceae)
The n-butanol phase of the methanolic leaves extract of Microtrichia perotitii DC was studied for its analgesic and anti-inflammatory activities. Both percent inhibition obtained from analgesic (59.30% for 100 mg/kg, 33.90% for 50 mg/kg and 69.20% for 25 mg/kg i.p) and anti-inflammatory (values for 25, 50 and 100 mg/kg were found significantly different at P < 05, P < 0.01 and P < 0.001) (mean paw...
May 2010
Antiprotozoal activity and cytotoxicity of metabolites from leaves of Teclea trichocarpa
Chromatographic separation of the leaves of Teclea trichocarpa (Engl.) Engl. (Rutaceae) used traditionally by Akamba tribe in Kenya yielded three acridone alkaloids, a furoquinoline alkaloid and two triterpenoids. The total extract (methanol) of the leaves of this plant and the isolated compounds were screened for in vitro for cytotoxicity and against parasitic protozoa, Plasmodium...
May 2010
Leonurus heterophyllus sweet extract improves hemorheology and inhibits thrombosis in rat with induced myocardial ischemia
The effects of Leonurus heterophyllus sweet (LHS) extract on hemorheological variables, platelet aggregation and thrombus formation ex vivo in rat with induced myocardial ischemia were investigated. Sixty male Sprague-Dawley rats were randomly and equally divided into 6 groups. Rats in Group III to Group VI received intravenously LHS extract one time a day and continuously for 7 days, the...
May 2010
Estrogen bioassy of Pueraria mirifica Airy Shaw and Suvatabandhu
Pueraria mirifica airy Shaw and Suvatabandhu has been used by Thai women for centuries as a rejuvenating herb. The scientific claim for its phytoestrogenic property leads to the popular use of this plant in several herbal formulations. This research project was carried out to examine estrogenic activity of P. mirificafrom Lampang Province, Thailand, one of the areas that it is harvested for using as raw...
May 2010
Anti-inflammatory activity of hot water extract of Berberis koreana in lipopolysaccharide-induced macrophage-like cells
Berberis koreana has been known as enthopharmacologically valuable plant in Korea, China and Japan. This plant has been reported to display numerous pharmacological activities such as anti-oxidative, neuroprotective, and anti-cancer effects. Although the pharmacological potentials have been demonstrated, anti-inflammatory effect of this plant has not been fully elucidated yet. To evaluate its anti-inflammatory activity,...
May 2010
Phytochemicals and uses of Moringa oleifera leaves in Ugandan rural communities
Moringa oleifera grown and used in many countries around the world is a multi-purpose tree with medicinal, nutritional and socio-economic values. In Senegal and Benin, M. oleifera leaves are dispensed as powder at health facilities to treat moderate malnutrition in children. It established the medicinal uses of M. oleiferaleaves by local communities in Uganda and identified phytochemicals...
May 2010
Nitric oxide interacts with reactive oxygen species to regulate oligosaccharide-induced artemisinin biosynthesis in Artemisia annua hairy roots
This work was to characterize the generation of nitric oxide (NO) and reactive oxygen species (ROS) in Artemisia annua roots induced by an oligosaccharide elicitor (OE) from Fusarium oxysporum mycelium and their relationship with artemisinin production. In the hairy root cultures, the OE at 0.3 mg total sugar/ml evoked a rapid production of nitric oxide synthase (NOS)-dependent NO and hydrogen...
May 2010
Some medicinal plants of Arabian Pennisula
Many nations of the world have traditional medicine. Arabs were the first to distil alcohol. The existence and use of plants to treat human diseases is as old as man. Some plants have opportunity, either to be or of being transferred from their original natural environment to another. To determine whether traditional medicines were available for the treatment of diseases in Arabian Pennisula, a literature review of the...
May 2010
An experimental evaluation of Albuca setosa aqueous extract on membrane stabilization, protein denaturation and white blood cell migration during acute inflammation
Albuca setosa is widely distributed in the Eastern Cape region of South Africa where its traditional usage is very extensive. This study was aimed to experimentally evaluate the effect of A. setosa water extract (ASWE) on inflammation events such as membrane stabilization, protein denaturation and white blood cell migration during acute inflammation. This study was undertaken...
May 2010
Phenolic content and antioxidant activities in red unpolished Thai rice prevents oxidative stress in rats
Radicals causd cellular damage and eventually progresse to chronic diseases. Phenolic compounds play a crucial role in radicals scavenging. In this study, we investigated total antioxidant activities, total phenolic content and profiles in color strains of unpolished Thai rice. The level of malondialdehyde was also assayed in rats that consumed unpolished Thai rice. Red color strain had the highest antioxidant...
May 2010
Alcohol extract of Pterogyne nitens leaves fails to reduce severity of streptozotocin-induced diabetes in rats
Two constituents of Pterogyne nitens leaves, kaempferitrin, a diglycosylated flavonol, and galegin, a guanidine alkaloid, may be considered likely to exert an antidiabetic effect, on the basis of their chemical structures. Thus, experimentally diabetic rats were treated with P. nitens leaf extract, to observe the effects on biochemical and toxicological marker variables. Streptozotocin-diabetic...
May 2010
Antifertility effects of aqueous crude extract of Ocimum gratissimum L. leaves in male mice
Ocimum gratissimum Linn. (OG) is widely used in folk medicine for several conditions because of its high medicinal value and therefore calls for its toxicological screening. The present study is designed to investigate the effects of aqueous leaf extract of OG on hormonal and semen parameters of mice. Animals were divided into 3 groups and orally administered OG (11 - 88 mg/kg) daily for 1, 2 and 4 weeks,...
May 2010
HPLC analysis and cytotoxic potential of extracts from the lichen, Thamnolia vermicularis var. subuliformis
The aim of this study was to investigate metabolites of the lichen Thamnolia vermicularis (Sw.) Schaer var. subuliformis (Ehrh.). Chloroform, ethyl acetate and methanol extracts of the lichen Thamnolia vermicularis var. subuliformiswere prepared and a high performance liquid chromatographic (HPLC) method was developed for the characterization of depsides in these...
May 2010
Effect of fermentation temperature and time on the chemical composition of bush tea (Athrixia phylicoides DC.)
A study was conducted to determine the effect of fermentation temperature and time on chemical composition of bush tea (Athrixia phylicoides DC.). Bush tea was fermented in incubators at different temperatures and for different times for quality improvement. Treatments for fermentation temperature consisted of control (24°C) room temperature, 30, 34, 38 and 42°C where the tea leaves were fermented...
May 2010
Genetic diversity of populations of an endangered medicinal plant species (Glycyrrhiza uralensis) in different environments of North China
Glycyrrhiza uralensis is an endangered and national-protected medicinal plant species distributed in semi-arid and arid areas of North China. This study addresses the genetic diversity and relationship between populations in different habitats by amplified fragment length polymorphism (AFLP). The plant materials consisted of 50 individuals from 5 different populating areas of Chifeng (Inner...
May 2010
Antibacterial activity and cytotoxicity of the leaf essential oil of Morus rotunbiloba Koidz
Essential oils from the leaf of Morus rotunbiloba Koidz was extracted and analysed using steam distillation and GC-MS. The results obtained indicated that the main components of the extracts are benzyl alcohol (10.48%),dihydroactinolide (10.11%) and palmitic acid (7.01%). The oil possessed strong antibacterial activity against Vibrio cholerae O139 DMST 9701, Samonella paratyphi A DMST...
May 2010
Phytochemical studies and antimicrobial screening of Schwenkia americana Linn.
The petroleum spirit (60 - 80°C), chloroform and methanol extracts of Schwenkia americana Linn. (Solanaceae) were screened for antimicrobial activity and for their chemical constituents. Phytochemical studies showed that it contained cardiac glycosides, saponins, steroids, triterpenes, flavonoids, cyanogenic glycosides, tannins and alkaloids. Antimicrobial screening showed that at 100 mg/ml, the methanol...
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