Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3804

Full Length Research Paper

Effect of aqueous ethanolic extract of Hymenocardia acida stem bark on oestrous cycle of albino rats

Abu A. H.1* and Uchendu C. N.2
1Department of Veterinary Physiology, Pharmacology and Biochemistry, College of Veterinary Medicine, University of Agriculture, P.M.B, 2373, Makurdi, Nigeria. 2Department of Veterinary Physiology and Pharmacology, Faculty of Veterinary Medicine, University of Nigeria, Nsukka, Nigeria.
Email: [email protected]

  •  Accepted: 07 March 2011
  •  Published: 18 April 2011


It is well known that some plant preparations play important role in fertility regulation. Oestrous cycles of albino rats showing regular cycles were monitored daily by vaginal lavage. The length of oestrus cycles and duration of each phase of the cycle were recorded. We observed that the aqueous ethanolic extract of Hymenocardia acida stem bark caused an irregular oestrous cycle characterised by prolonged diestrus phase. It is concluded that the extract caused a loss of cyclicity in female albino rats.


Key wordsHymenocardia acida, albino rats, oestrous cycle.