Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3834

Table of Content: 18 April 2011; 5(8)

April 2011

Jerusalem artichoke (Helianthus tuberosus), a medicinal salt-resistant plant has high adaptability and multiple-use values

Jerusalem aritichoke (Helianthus tuberosus) is an Angiosperm plant species of the Compositae family, and a C-3 warm-season species of sunflower. This herbaceous plantshows significant ecological and commercial importance for its strong stress tolerance, very high yield potential and more application areas such as chemicals, pharmaceuticals and industrial applications. The morphologic, bio-ecological characteristics, the...

Author(s): Xiao Yong Ma, Li Hua Zhang, Hong Bo Shao, Gang Xu, Feng Zhang, Fu Tai Ni and M. Brestic

April 2011

Effect of aqueous ethanolic extract of Hymenocardia acida stem bark on oestrous cycle of albino rats

It is well known that some plant preparations play important role in fertility regulation. Oestrous cycles of albino rats showing regular cycles were monitored daily by vaginal lavage. The length of oestrus cycles and duration of each phase of the cycle were recorded. We observed that the aqueous ethanolic extract of Hymenocardia acida stem bark caused an irregular oestrous cycle characterised by prolonged...

Author(s): Abu A. H. and Uchendu C. N.

April 2011

Gender dimension of herbal medicine’s knowledge and practice in Ekiti and Ondo States, Nigeria

In Nigeria several occupations and practices are gender biased right from their names and references. The womenfolk are not heard of but it was discovered that in almost all local markets in Nigeria, women engage in the sales of herbal products for the treatment of numerous ailments however, there are no available data of their contributions to herbal medicine. It is on this note that this study was carried out to...

Author(s): G. M. Adebo and S. D. Y. Alfred

April 2011

Flavone C-glycosides from Montanoa bipinnatifida stems and evaluation of hepatoprotective activity of extract

The methanolic extract of the stems of Montanoa bipinnatifida was investigated for its phenolic compounds and hepactoprotective activity. A new flavon C-glycosides named as luteolin 6-C- apioside 8-C- glucoside (1) as well as apigenin 6-C-glucoside(2), apigenin 8-C-glucoside(3), apigenin 6,8- di-C-glucoside(4), luteolin 8-C-glucoside(5) luteolin 6,8- di-C-glucoside(6), luteolin 6-C- glucoside(7), apigenin(8)...

Author(s): Sayed A. El-Toumy, Enayat A. Omara, Somaia A. Nada and Jame Bermejo

April 2011

Medicinal plants used in Northern Peru for the treatment of bacterial and fungal infections and inflammation symptoms

A total of 96 plant species belonging to 84 genera and 46 families were documented and identified as anti-infective herbal remedies in Northern Peru. Most species used were Asteraceae (18 species, 18.95%), followed by Fabaceae and Euphorbiaceae (7.37% and 5.26%). The most important anti-infectious families are somewhat over-represented in comparison to the overall medicinal flora, while some other medicinally important...

Author(s): Rainer W. Bussmann and Ashley Glenn

April 2011

Inhibitory and apoptosis-inducing effects of Lophophora williamsii extracts on HeLa cells

The in vitro inhibitory and apoptosis-inducing effects of three different Lophophora williamsiiextracts were observed in HeLa cells. Methanol, hydrochloric acid, and sodium hydroxide were used to extract active compounds from the caudices of L. williamsii. The inhibitory effects of the extracts on HeLa cells were detected by Methyl Thiazolyl Tetrazolium (MTT) assay and the apoptosis-inducing effects...

Author(s): Zuo Zhi-yu, Song Xiao-tao, Zhang Hao-peng, Shi Xue-li, Zhang Yao, Zhang Jing-wei, Xu Huan-lin, Sun Tao and Zhou Bao-kuan

April 2011

Rapid determination of cinnamic acid and harpagoside in a traditional Chinese medicine of Scrophularia ningpoensis by microwave-assisted extraction followed by high performance liquid chromatography (HPLC)

Cinnamic acid and harpagoside are important active components present in Scrophularia ningpoensis, which has been used in the treatment of several diseases such as pharyngalgia. In the present study, a novel method based on high performance liquid chromatography (HPLC) following microwave-assisted extraction (MAE) was developed for the determination of cinnamic acid and harpagoside in a traditional Chinese medicine...

Author(s): Taomin Huang, Nianzu Chen, Yonghua Lai, Donglei Wang, Jinchao Yan and Jifeng Gu

April 2011

Biological activities and phytoconstituents of the lower plant Platycerium angolense, Welwex Hook

Lower plants are regarded as unstudied portion of plant kingdom that are not traditionally employed for healing, treatment and management of ailments in folklore medicine. The ethanolic extract of Platycerium angolense, Welwex Hook was phytochemically screenedand analyzed for flavonoid content with a view to investigating its biological activities. The flavonoid fractions were assayed for anti-oxidant, 1,...

Author(s): Sikiru Olatunji Bode and Oluboade Oluokun Oyedapo

April 2011

Pharmacognostic evaluations of Lagerstroemia speciosa leaves

The current study was conducted to develop the pharmacognostic standards forLagerstroemia speciosa leaves. These evaluations were performed according to the World Health Organization (WHO) guidelines and the Thai Herbal Pharmacopoeia (THP) for herbal standardisation. No other reports are available on the pharmacognostic evaluation of the leaves of L. speciosa (L.) Pers. Organoleptic, and we thus reported...

Author(s): Woratouch Thitikornpong, Thatree Phadungcharoen and Suchada Sukrong,

April 2011

In vitro Antimicrobial activities of chloroformic, hexane and ethanolic extracts of Citrullus lanatus var. citroides (Wild melon)

To test the antimicrobial activities of  crude chloroform, hexane and ethanol extracts of leaves, stem, fruits and seeds from Citrullus lanatus var. citroides (CL) against bacteria (Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis andProteus vulgaris) and fungi (Aspergillus nigar and Candida albican). Antimicrobial properties of CL were...

Author(s): Loiy Elsir Ahmed Hassan, Hasnah Mohd Sirat, Sakina M. Ahemd Yagi, Waleed S. Koko, and Siddig Ibrahim Abdelwahab

April 2011

Mutagenic and antimutagenic activities of Mitragyna speciosa Korth extract using Ames test

Mitragyna speciosa Korth (Ketum) is a medicinal plant that has been used traditionally to enhance energy, cure illnesses, fever and diarrhea. Aqueous extract of M. speciosa was screened for the potential of mutagenic and antimutagenic activity using Ames test (Salmonella/microsome mutagenicity assay). Ames test involved the pre-incubation assay against Salmonella typhimurium TA 98...

Author(s): A. R. Ghazali, R. Abdullah, N. Ramli , N. F. Rajab , M. S. Ahmad-Kamal and N. A. Yahya

April 2011

Relationships among six medicinal species of Curcuma assessed by RAPD markers

The random amplified polymorphic DNA (RAPD) markers were applied to detect the genetic relationships and diversity among 33 accessions of Curcuma species in China, which involved six medicinal species. A total of 115 products were amplified by 21 primers, among which 106 products (92.17%) were found to be polymorphic. 3 to 8 polymorphic bands were amplified by each polymorphic primer, with an average of 5.48...

Author(s): Xuemei Zou, Zhuojun Dai, Chunbang Ding, Li Zhang, Yonghong Zhou and Ruiwu Yang

April 2011

Synergism of artemisinin with abyssinone –V from Erythrina abyssinica (Lam. ex) against Plasmodium falciparum parasites: A potential anti-malarial combination therapy

A Plasmodium falciparum in vitro drug sensitive study was conducted in order to evaluate artemisinin in combination with potential anti-malarial drug from the stem bark of Erythrina abyssinica. Abyssinone-v was isolated and thus identified as a potential partner for a fixed combination therapy. Bioassay guided chromatographic separation of Ethyl acetate extract of Erythrina...

Author(s): J. S. Kebenei, P. K. Ndalut and A. O. Sabah

April 2011

Antioxidant and antifungal activity of some aromatic plant extracts

In this study, the antioxidant and antifungal activities of extracts of sage, rosemary, basil, laurel, pickling herb and summer savory were established. Total yields, radical scavenging activity and the antioxidant capacities of the extracts were determined. The free radical scavenging activities of extract was established as 42.3±3.1 to 78.9±7.1%, respectively. The antioxidant capacities of...

Author(s): Mehmet Musa Özcan and Fahad Y. AL Juhaimi

April 2011

Medicinal uses of Berberis holstii Engl. (Berberidaceae) in Malawi, the only African endemic barberry

Berberis species are medicinally important due to the presence of alkaloids with different pharmacological activities. There are about 500 species of Berberis worldwide and only two are present in Africa namely: Berberis vulgaris (also present in Europe) and Berberis holstii(the only African endemic). The present study investigated utilization practices of B. holstii,a plant...

Author(s): Cecilia Promise Maliwichi-Nyirenda, Lucy Lynn Maliwichi and Miguel Franco

April 2011

Genetic diversity of wild Auricularia polytricha in Yunnan Province of South-western China revealed by sequence-related amplified polymorphism (SRAP) analysis

As an economically and medically important fungus, Auricaularia polytricha has been collected and cultivated widely in China, however, its diversity has not yet investigated previously. The genetic diversity of 20 wild A. polytricha strains from Yunnan Province and four cultivated strains from Henan and Sichuan Province were profiled by using 10 pairs of sequence-related amplified polymorphism (SRAP)...

Author(s): P. Du, B. K. Cui and Y. C. Dai

April 2011

Cytotoxicity activity of extracts and compounds from Commiphora myrrha resin against human gynecologic cancer cells

The purpose of this report is to explore the cytotoxicity effects of extracts and compounds from Commiphora myrrha resin on human gynecologic cancer cells. The results showed that AE (85% EtOH extract), and petroleum ether extract (PE) from C. myrrha significantly inhibited cell proliferation of A2780, SK-OV-3, and Shikawa with dose-dependent relation in vitro. The inhibitory effects of AE...

Author(s): Shulan Su, Tuanjie Wang, Ting Chen, Jin-ao Duan, Li Yu and Yuping Tang

April 2011

Study of antihyperlipidemic effect on rabbits of 8-alkylberberine derivatives

To study the antihyperlipidemic effect of 8-alkyl-berberine derivatives (8-BBR-Cn). The experimental hyperlipidemia rabbits were prepared by feeding with high cholesterol and high fat (HCHF) diet. Then the effects of 8-alkyl-BBR on the serum levels of total cholesterol (TC), triglyceride (TG), (HDL-C), low density lipoprotein-cholesterol...

Author(s): Xiaoli Ye, Xin Chen, Kai He, Jun Yi, Xuegang Li, Ping Li and Xiaohong Wang

April 2011

In vitro cytotoxic potential of Swietenia macrophylla King seeds against human carcinoma cell lines

Fruits of Swietenia macrophylla King (sky fruit) have been widely used in traditional medicine to treat various diseases including hypertension and diarrhea. The cytotoxic activity of the crude ethanol extract of the seeds of S. macrophylla and its fractions was assessed against selected human cancer cell lines, namely, HCT 116 (colon carcinoma), KB (nasopharyngeal epidermoid carcinoma), Ca Ski...

Author(s): Bey Hing Goh and Habsah Abdul Kadir    

April 2011

Chemotaxis movement assay of Eurycoma longifolia using wild and disarmed strains of Agrobacterium rhizogenes

Bacterial chemotaxis is considered the first step in the interaction between motile bacteria and plant cells. Chemotaxis initiates the process of bacterial infection towards the plant cells and thus conferring beneficial attributes to the host. In this study, 5 wild strains and 2 disarmed strains of Agrobacterium rhizogenes were tested for chemotaxis assay using the swarm agar plate method. As expected, strong...

Author(s): Monica Danial, Chan Lai Keng, Syarifah Shahrul Rabiah Syed Alwee, Maziah Mahmood and Sreeramanan Subramaniam

April 2011

Cadmium-induced changes in growth and antioxidative mechanisms of a medicine plant (Lonicera japonica Thunb.)

The responses of a medicine plant (Lonicera japonica Thunb.) to different cadmium (Cd) levels in the nutrient medium were studied. The results showed that the high Cd concentrations accumulated in roots and shoots of L. japonica, which increased ediblesecurity risk of the plant. The chlorophyll content showed slightly increase in plants exposed to 5 mg L-1 Cd, but...

Author(s): Zhouli Liu, Wei Chen and Xingyuan He

April 2011

The inhibitory effect of Opuntia humifusa Raf. ethyl acetate extract on platelet aggregation

This study was designed to investigate the activity of ethyl acetate extract from Opuntia humifusa Raf. (OH-EAE) in ligand-activated platelet aggregation. Platelet aggregation was induced either by ADP, a potent agonist to platelet G protein-coupled P2Y receptor, by collagen, a potent ligand that activates platelet integrin α2β1 and glycoprotein VI, or thrombin, a platelet protease-activated...

Author(s): Won-Jun Oh, Mehari Endale, Ji-Young Park, Yi-Seong Kwak, Suk Kim, Gon-Sup Kim and Man Hee Rhee

April 2011

Aqueous extract of Panax notoginseng affecting blood TC, TG and ET-1 levels in postoperative rabbits

This study was designed to test the postoperative protective effects of Panax notoginsengextract in rabbits. Carotic artery injury was induced by surgery in rabbits and then fed withP. notoginseng extract for 8 weeks. The serum TC, TG and ET-1 levels were examined. Results showed that administration of aqueous extracts of P. notoginseng significantly lowered the serum levels of TC, TG and ET-1. These...

Author(s): Yaling Wang, Jianlin Tang, Yong Pan and Tiande Yang

April 2011

Inhibition of HSP90 by triptolide (TPL) augments Bortezomib-induced U266 cells apoptosis

HSP90 has high expression in myeloma cells and very important for prognosis, and that triptolide (TPL), the main active component of the traditional Chinese herbal medicineTripterygium wilfordii Hook F (Celastraceae) has the inhibition effects in the growth of myeloma cells. In this study, we test the ability of TPL to induce apoptosis in U266 human myeloma cells by reducing HSP90 expression, as well as the effect...

Author(s): Dan Shen, Xiangmin Tong, Junyu Zhang, Panhan Zhang, Jie Jin, Xiangli Gao and Chengjian Ma

April 2011

In vitro and in vivo inhibitory action of a novel antibiotic on mouse hepatoma H22

IC50 for a novel antibiotic against mouse hepatoma H22 was determined to be 0.019 μg/mL by MTT assays. In KM mice bearing this kind of tumor that was treated by s.c. injection of antibiotic BS, marked cures were obtained. In terms of tumor weight, the treated/control=0.35. The conclusion is that BS merit further investigation as a potential anti-cancer candidate drug.   Key words: Bacillus...

Author(s): Chen-Xiaoxi

April 2011

Antioxidative and hypolipidemic effects of lactic acid bacteria from pickled Chinese cabbage

Pickled cabbage is a popular Chinese traditional food. The present study was explored to characterize effects of lactic acid bacteria (LAB) isolated from the pickled cabbages on activities of antioxidant enzymes and hypolipidemia in normal and hyperlipidemic mice. 28 LAB strains were isolated from pickled cabbage, and two strains with high acid tolerance and bile salt resistance were screened. The strains were...

Author(s): Dawei Gao, Guanghua Zhu, Zhengrong Gao, Zhiwei Liu, Lixin Wang and Wei Guo

April 2011

An ethnobotanical study of medicinal plants used in the Kalamaloué National Park, Cameroon

An ethnobotanical survey was conducted from 1st April to 30th September 2005 among populations living inside and around the National Park of Kalamaloué in the far north of Cameroon. The survey aimed at identifying the plants used in the general pharmacopoeia among local ethnic groups using interviews with households who have a rich knowledge on the plants. A total of 36 medicinal plants were recorded from 37...

Author(s): J. L. Betti and S. R. Mebere Yemefa’a

April 2011

Isolation and structural elucidation of chemical constituents of Mussaenda hainanensis Merr.

To study the chemical constituents of Mussaenda hainanensis Merr. and also researched the EtOAc, n-BuOH and H2O extract of 70% EtOH extract on DPPH radicals scavenging effect. The compounds were isolated by Diaion HP-20, Sephadex LH-20, Toyopearl HW-40 and Si gel column chromatography methods. Their structures were identified by physicochemical properties and spectroscopic analysis. Twelve compounds were...

Author(s): Yu-xian Li, Wen-tao Qiao and Ke Yuan

April 2011

Chemical composition and in vitro antioxidant properties of essential oil of Ricinus communis L.

The essential oil from the aerial parts of Ricinus communis, an aromatic member of the Euphorbiaceae family, from Tunisia, obtained by hydrodistillation, was analyzed by gas chromatography coupled to mass spectrometry (GC-MS). Seven constituents were found representing 100% of the oil. The main constituents of the essential oil were α-thujone (31.71%), 1,8-cineole (30.98%), followed by...


April 2011

Medico-botanical and chemical standardization of pharmaceutically important plant of Tricholepis chaetolepis (Boiss) Rech. f.

Medico-botanical and chemical standardization of Barham Dandi (Tricholepis chaetolepis(Boiss) Rech. f.), a pharmaceutical herbal drug and its adulterants has been carried out. The study includes parameters such as macro-micromorphology of species, pollen (SEM), organoleptography, fluorescence analysis (UV and IR) and certain physico-chemical aspects that is flavonoids finger printing by 2 D thin layer chromatography....

Author(s): Mir Ajab Khan, Mushtaq Ahmad, Muhammad Zafar, Shazia Sultana, Sarfaraz Khan Marwat, Shabnum Shaheen, Muhammad Khan Leghari, Gul Jan, Farooq Ahmad and Abdul Nazir

April 2011

Preventive effect of Nigella sativa on metabolic syndrome in menopause induced rats

In women facing menopause, end of menstrual activity is accompanied by lower levels of estrogen and gradual weight gain. Postmenopausal weight gain sounds an alarm for women’s health and may lead to hyperlipidemia, a lipid increase and glucose intolerance. These phenomena are connected to lifestyle-related diseases such as hypertension, type II diabetes mellitus, arteriosclerosis and metabolic syndrome, making it...

Author(s): Saadat Parhizkar, Latiffa A. Latiff, Sabariah A.Rahman, and Mohammad A. Dollah

April 2011

The physicochemical properties and oil (Silybum marianum Gaertn. cv. Budakalászi) constituents of milk thistle under drought stress

Milk thistle, Silybum marianum, is an annual or biennial plant. It has been reported that the extracted oil from milk thistle seed contains essential edible fatty acids. The aim of the present study was to determine the irrigation interval effects on different fatty acids content of milk thistle. Irrigation intervals consisted of D1= 5, D2= 10, D3= 15 days and D4= without irrigation. To show the water status...

Author(s): M. Malekzadeh, S. I. Mirmazloum, H. Rabbi Anguorani, S. N. Mortazavi and M. Panahi

April 2011

Phytodiversity and endemic richness in high altitude Rama Valley, Western Himalayas, Northern Pakistan

Vegetation diversity, distribution and species endemism were studied in high altitude (>3300 m) Himalayan plateau in Northern Pakistan. A heterogeneous vegetation structure and distribution was observed due to complex environmental variables. A total of 83 species belonging to 31 families were recorded from the area. The recorded range of species diversity (1.02 to 2.17) and species richness (1.19 to 1.97) was very...

Author(s): Hamayun Shaheen, Naseer Ahmad, Naveed Alam, Khalid Ahmed and Zahid Ullah

April 2011

Monograph of Apium graveolens Linn.

Apium graveolens has been used in Unani system of medicine as anti-inflammatory, uricosuric, diuretic and to treat rheumatism besides other ailments. The description, active constituents, medical uses A. graveolens are described herewith.   Key words: Apium graveolens, active constituents, medicinal activity.

Author(s): H. M. Asif, M. Akram, Khan Usmanghani, Naveed Akhtar, Pervaiz A. Shah, M. Uzair, Memona Ramzan, S. M. Ali Shah, and Riazur Rehman