Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3693

Full Length Research Paper

In vitro antimicrobial activity and fatty acid composition through gas chromatography-mass spectrometry (GC-MS) of ethanol extracts of Mauritia flexuosa (Buriti) fruits

Adriana Idalina Torcato de OLIVEIRA
  • Adriana Idalina Torcato de OLIVEIRA
  • Laboratório de Microbiologia Ambiental e Biotecnologia (LAMBIO), Universidade Federal do Tocantins, P. O. Box 114, 77001-923, Palmas, TO, Brazil.
  • Google Scholar
Jhonatha Barros CABRAL
  • Jhonatha Barros CABRAL
  • Laboratório de Microbiologia Ambiental e Biotecnologia (LAMBIO), Universidade Federal do Tocantins, P. O. Box 114, 77001-923, Palmas, TO, Brazil.
  • Google Scholar
Talal Suleiman MAHMOUD
  • Talal Suleiman MAHMOUD
  • Centro de Estudos do Mar (CEM) – UFPR. 83255-976. Caixa Postal: 61. Av. Beira Mar, s/n, Balneário Pontal do Sul. Pontal do Paraná, PR, Brazil.
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Guilherme Nobre L. do NASCIMENTO
  • Guilherme Nobre L. do NASCIMENTO
  • Laboratory of Basic and Health Sciences, Federal University of Tocantins, 77001-923, Palmas, TO, Brazil.
  • Google Scholar
Juliana Fonseca Moreira da SILVA
  • Juliana Fonseca Moreira da SILVA
  • Laboratório de Microbiologia Ambiental e Biotecnologia (LAMBIO), Universidade Federal do Tocantins, P. O. Box 114, 77001-923, Palmas, TO, Brazil.
  • Google Scholar
Raphael Sanzio PIMENTA
  • Raphael Sanzio PIMENTA
  • Laboratório de Microbiologia Ambiental e Biotecnologia (LAMBIO), Universidade Federal do Tocantins, P. O. Box 114, 77001-923, Palmas, TO, Brazil.
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Paula Benevides de MORAIS
  • Paula Benevides de MORAIS
  • Laboratório de Microbiologia Ambiental e Biotecnologia (LAMBIO), Universidade Federal do Tocantins, P. O. Box 114, 77001-923, Palmas, TO, Brazil.
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  •  Received: 03 August 2017
  •  Accepted: 05 October 2017
  •  Published: 25 October 2017

Abstract

In this study, the chemical composition of the peel and pulp of Mauritia flexuosa fruits were analyzed and the antimicrobial activity of ethanolic extracts from these fruits was evaluated using in vitro tests. Chemical composition analysis with gas chromatography-mass spectrometry (GC-MS) indicated the presence of saturated and unsaturated fatty acids. The peel extracts (ECBU) presented 54.41% and the pulp (EPBU) presented 94.05% of the saturated fatty acids lauric, myristic, palmitic, stearic, oleic and linoleic acids. The antimicrobial activities were performed using the diffusion and micro-dilution (MIC) methods. ECBU was active against the bacteria Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa and Staphylococcus aureus at a concentration of 200 mg mL-1, but it was not active against the yeasts Candida albicans and Candida parapsilosis using the diffusion method. The MIC results showed that ECBU was active against the tested bacteria at concentrations > 12.5 mg mL-1 and EPBU was active at concentrations > 25.0 mg mL-1. This was probably due to higher sensibility of the method. The results indicated that the peel and pulp extracts of M. flexuosa present antibacterial activity and that ECBU is an especially promising potential candidate for the prospection of new pharmaceutical compounds.

 

Key words: Mauritia flexuosa, Buriti, anti-bacterial agents, fatty acids.

Abbreviation

ECBU, Ethanolic extract of Buriti bark; EPBU, ethanolic extract of Buriti pulp; MIC, minimum inhibitory concentration; G+, gram positive; G-, gram negative; GC-MS, gas chromatography coupled to mass spectrometer; DMSO, Dimethylsulfoxide; ATCC, American type collection culture; CFU, colony forming unit; CLSI, Clinical and Laboratory Standards Institute.