Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Isolation and characterization of terpene from leaves of Croton macrostachyus (Bissana)

Abeje Abebayehu*
  • Abeje Abebayehu*
  • Department of Chemistry, College of Natural and Computational Sciences, Wolaita Sodo University, P. O. Box 138, W/Sodo, Ethiopia.
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Fikre Mammo
  • Fikre Mammo
  • Biochemistry Units, College of Health Sciences, Hawassa University, P. O. Box 05, Hawassa, Ethiopia.
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Belayhun Kibret
  • Belayhun Kibret
  • Department of Chemistry, College of Natural and Computational Science, Hawassa University, P. O. Box 05, Hawassa, Ethiopia.
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  •  Received: 26 February 2016
  •  Accepted: 19 March 2016
  •  Published: 17 May 2016

Abstract

Croton macrostachyus, one of the Croton species found in Ethiopia, is used traditionally for treatment of a number of health ailments including diabetes, malaria, stomachache, ascariasis, abdominal pain, gonorrhea, wounds, ringworm infestation and hemorrhoids. In the present study, phytochemical screening of ethanol extract from leaves of C. macrostachyus revealed the presence of terpenes, flavonoids, alkaloids and saponins. Silica gel column chromatographic separation of the ethanol extract afforded a pentacyclic triterpeniod reported for the first time from the genus. The structure of the compound was determined using combination of spectroscopic techniques via UV-Vis, IR, 1H NMR, 13C NMR and DEPT-135.

Key words: Croton macrostachyus, pentacyclic triterpenoids, anti-malaria, spectroscopic techniques, phytochemical screening.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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