Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3758

Full Length Research Paper

Pharmacological screening of Morchella esculenta (L.) Pers., Calvatia gigantea (Batsch ex Pers.) Lloyd and Astraeus hygrometricus Pers., mushroom collected from South Waziristan (FATA.)

Hussain Badshah1, Rizwana Aleem Qureshi1, Javed Khan2, Farman Ullah3, Shah Fahad1, Faizan Ullah1, Amir Muhammad Khan4, Ishtiaq Hussain1* and Naeem Khan1
1Department of Plant Sciences, Faculty of Biological Sciences, Quaid-I-Azam University Islamabad, Pakistan. 2National Agricultural Research Centre, Islamabad, Pakistan. 3Department of Physiology, Kohat Institute of Medical Sciences, University of Science and Technology Kohat, Pakistan. 4Department of Plant Sciences, Kohat University of Science and Technology, Kohat KPK, Pakistan.
Email: [email protected]

  •  Accepted: 11 October 2011
  •  Published: 16 March 2012

Abstract

The mushrooms were screened for their antimicrobial, and cytotoxicity, six strains of bacteria viz. Staphylococcus aureus (ATCC6538), Bacillus subtilis (ATCC6633), Vibrio cholerae(ATCC6643), Escherichia coli (ATCC15224), Klebsiella pneumoniae (MTCC618) andEnterobacter aerogenes (ATCC13048) were utilized as test organisms for determination of antibacterial activity. Maximum antibacterial activity was observed at 30 mg/ml concentration of extracts. Greater inhibitory activity against S. aureus was possessed by methanolic and ethanolic extracts of Calvatia gigantean. The methanolic extract of Morchella esculentaexhibited maximum inhibitory activity against V. cholerae and also the ethanolic extract showed higher bactericidal activity against E. coli. But the selected mushrooms exhibited no significant antifungal activity against Aspergillus fumigatus and Aspergillus niger.

 

Key words: Mushrooms, medicinal, South Waziristan Agency.