Review
Abstract
Artemisinin was the most effective antimalarial drug in the world and it was a sesquiterpene lactone extracted from a traditional Chinese medicinal herb, Artemisia annua L., Due to its great antimalarial activity but extremely low content of wild-type A. annua plants, many research groups had focused on enhancing the content of artemisinin in A. annua plants. In this review, it mainly discussed the recent research advances on several different metabolic regulation approaches for enhanced artemisinin production.
Key words: Artemisia annua, artemisinin, metabolic regulation, biosynthetic pathway.
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