Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Effect of Ephedra foeminea active compounds on cell viability and actin structures in cancer cell lines

Maayan Mendelovich
  • Maayan Mendelovich
  • Institute of Plant Sciences, Agriculture Research Organization, Volcani Center, Rishon LeZion 75822, Israel.
  • Search for this author on:
  • Google Scholar
Monick Shoshan
  • Monick Shoshan
  • Institute of Plant Sciences, Agriculture Research Organization, Volcani Center, Rishon LeZion 75822, Israel.
  • Search for this author on:
  • Google Scholar
Marcelo Fridlender
  • Marcelo Fridlender
  • Institute of Plant Sciences, Agriculture Research Organization, Volcani Center, Rishon LeZion 75822, Israel.
  • Search for this author on:
  • Google Scholar
Moran Mazuz
  • Moran Mazuz
  • Institute of Plant Sciences, Agriculture Research Organization, Volcani Center, Rishon LeZion 75822, Israel.
  • Search for this author on:
  • Google Scholar
Dvora Namder
  • Dvora Namder
  • Institute of Plant Sciences, Agriculture Research Organization, Volcani Center, Rishon LeZion 75822, Israel.
  • Search for this author on:
  • Google Scholar
Rameshprabu Nallathambi
  • Rameshprabu Nallathambi
  • Institute of Plant Sciences, Agriculture Research Organization, Volcani Center, Rishon LeZion 75822, Israel.
  • Search for this author on:
  • Google Scholar
Gopinath Selvaraj
  • Gopinath Selvaraj
  • Institute of Plant Sciences, Agriculture Research Organization, Volcani Center, Rishon LeZion 75822, Israel.
  • Search for this author on:
  • Google Scholar
Puja Kumari
  • Puja Kumari
  • Institute of Plant Sciences, Agriculture Research Organization, Volcani Center, Rishon LeZion 75822, Israel.
  • Search for this author on:
  • Google Scholar
Aurel Ion
  • Aurel Ion
  • Institute of Plant Sciences, Agriculture Research Organization, Volcani Center, Rishon LeZion 75822, Israel.
  • Search for this author on:
  • Google Scholar
Smadar Wininger
  • Smadar Wininger
  • Institute of Plant Sciences, Agriculture Research Organization, Volcani Center, Rishon LeZion 75822, Israel.
  • Search for this author on:
  • Google Scholar
Ahmad Nasser
  • Ahmad Nasser
  • The Interinstitutional Analytical Instrumentation Unit (IU), Agriculture Research Organization, Volcani Center, Rishon LeZion 75822, Israel.
  • Search for this author on:
  • Google Scholar
Mohamed Samara
  • Mohamed Samara
  • The Interinstitutional Analytical Instrumentation Unit (IU), Agriculture Research Organization, Volcani Center, Rishon LeZion 75822, Israel.
  • Search for this author on:
  • Google Scholar
Yaacov Sharvit
  • Yaacov Sharvit
  • Institute for Apitherapy, Department of Medicinal Plants and Natural Compounds, Tu Beav 181, Shiloh, 4483000, Israel.
  • Search for this author on:
  • Google Scholar
Yoram Kapulnik
  • Yoram Kapulnik
  • Institute of Plant Sciences, Agriculture Research Organization, Volcani Center, Rishon LeZion 75822, Israel.
  • Search for this author on:
  • Google Scholar
Native Dudai
  • Native Dudai
  • The Unit of Aromatic and Medicinal Plants, Newe Yaar Research Center, ARO, Ramat Yishai 30095, Israel.
  • Search for this author on:
  • Google Scholar
Hinanit Koltai
  • Hinanit Koltai
  • Institute of Plant Sciences, Agriculture Research Organization, Volcani Center, Rishon LeZion 75822, Israel.
  • Search for this author on:
  • Google Scholar


  •  Received: 19 August 2017
  •  Accepted: 24 October 2017
  •  Published: 17 November 2017

References

Abourashed EA, El-Alfy AT, Khan IA, Walker L (2003). Ephedra in perspective – a current review. Phytother. Res. 17:703-712.
Crossref
 

Ali-Shtayeh MS, Jamous RM, Salameh NM, Jamous RM, Hamadeh AM (2016). Complementary and alternative medicine use among cancer patients in Palestine with special reference to safety-related concerns. J. Ethnopharmacol. 187:104-122.
Crossref

  
 

Arocho A, Chen B, Ladanyi M, Pan Q (2006). Validation of the 2-ΔΔCt calculation as an alternate method of data analysis for quantitative PCR of BCR-ABL P210 transcripts. Diagn. Mol. Pathol. 15:56-61.
Crossref

  
 

Astrup A, Breum L, Toubro S (1995). Pharmacological and clinical studies of ephedrine and other thermogenic agonists. Obes. Res. 3:537-540.
Crossref

  
 

Ben-Arye E, Mahajna J, Aly R, Ali-Shtayeh MS, Bentur Y, Lev E, Deng G, Samuels N (2016). Exploring an herbal "wonder cure" for cancer: a multidisciplinary approach. J. Cancer Res. Clin. Oncol. 142(7):1499-1508.
Crossref

  
 

Foda HD, Zucker S (2001). Matrix metalloproteinases in cancer invasion, metastasis and angiogenesis. Drug Discov. Today 6:478-482.
Crossref

  
 

Gurley BJ, Wang P, Gardner SF (1998). Ephedrine‐type alkaloid content of nutritional supplements containing Ephedra sinica (ma‐huang) as determined by high performance liquid chromatography. J. Pharm. Sci. 87:1547-1553.
Crossref

  
 

Halket JM, Waterman D, Przyborowska AM, Patel RK, Fraser PD, Bramley PM (2004). Chemical derivatization and mass spectral libraries in metabolic profiling by GC/MS and LC/MS/MS. J. Exp. Bot. 56:219-243.
Crossref

  
 

Ickert-Bond SM, Rydin C, Renner SS (2009). A fossil‐calibrated relaxed clock for Ephedra indicates an Oligocene age for the divergence of Asian and New World clades and Miocene dispersal into South America. J. Syst. Evol. 47:444-456.
Crossref

  
 

Kamath K, Smiyun G, Wilson L, Jordan MA (2014). Mechanisms of inhibition of endothelial cell migration by taxanes. Cytoskeleton (Hoboken) 71:46-60.
Crossref

  
 

Kobayashi S, Endou M, Sakuraya F, Matsuda N, Zhang XH, Azuma M, Echigo N, Kemmotsu O, Hattori Y, Gando S (2003). The sympathomimetic actions of l-ephedrine and d-pseudoephedrine: direct receptor activation or norepinephrine release? Anesth. Analg. 97:1239-1245.
Crossref

  
 

Krizevski R, Bar E, Shalit OR, Levy A, Hagel JM, Kilpatrick K, Marsolais F, Facchini PJ, Ben-Shabat S, Sitrit Y, Lewinsohn E (2012). Benzaldehyde is a precursor of phenylpropylamino alkaloids as revealed by targeted metabolic profiling and comparative biochemical analyses in Ephedra spp. Phytochemistry 81:71-79.
Crossref

  
 

Mayzlish-Gati E, Laufer D, Grivas CF, Shaknof J, Sananes A, Bier A, Ben-Harosh S, Belausov E, Johnson MD, Artuso E, Levi O, Genin O, Prandi C, Khalaila I, Pines M, Yarden RI, Kapulnik Y, Koltai H (2015). Strigolactone analogs act as new anti-cancer agents in inhibition of breast cancer in xenograft model. Cancer Biol. Ther. 16:1682-1688.
Crossref

  
 

Mehner C, Hockla A, Miller E, Ran S, Radisky DC, Radisky ES (2014). Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer. Oncotarget 5:2736-2749.
Crossref

  
 

Nagappan R (2012). Evaluation of aqueous and ethanol extract of bioactive medicinal plant, Cassia didymobotrya (Fresenius) Irwin & Barneby against immature stages of filarial vector, Culex quinquefasciatus Say (Diptera: Culicidae). Asian Pac. J. Trop. Biomed. 2(9):707-711.
Crossref

  
 

Normile D (2003). The new face of traditional Chinese medicine. Science 299:188-190.
Crossref

  
 

Schiff PB, Fant J, Horwitz SB (1979). Promotion of microtubule assembly in vitro by Taxol. Nature 277:665-667.
Crossref

  
 

Snyder LR, Kirkland JJ, Glajch JL (2012). Practical HPLC method development. John Wiley & Sons.

  
 

Yamaguchi H (2012). Pathological roles of invadopodia in cancer invasion and metastasis. Eur. J. Cell Biol. 91:902-907.
Crossref

  
 

Yamaguchi H, Condeelis J (2007). Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochim. Biophys. Acta 1773:642-652.
Crossref

  
 

Yeung AY (1980). Encyclopedia of common natural ingredients. John Willey & Sons, New York, USA. pp. 166-167.

  
 

Yvon AMC, Wadsworth P, Jordan MA (1999). Taxol suppresses dynamics of individual microtubules in living human tumor cells. Mol. Biol. Cell. 10:947-959.
Crossref

  
 

Zhao Y, Hao X, Lu W, Cai J, Yu H, Sevénet T, Guéritte F (2002). Syntheses of two cytotoxic sinapyl alcohol derivatives and isolation of four new related compounds from Ligularia nelumbifolia. J. Nat. Prod. 65:902-908.
Crossref

  
 

Zhao Y, Zhongjian J, Yang L (1994). Sinapyl alcohol derivatives and other constituents from Ligularia Nelumbifolia. Phytochemistry 37:1149-1152.
Crossref

  
 

Zou HB, Dong SY, Zhou CX, Hu LH, Wu YH, Li HB, Gong JX, Sun LL, Wu XM, Bai H, Fan BT, Hao XJ, Stöckigt J, Zhao Y (2006). Design, synthesis, and SAR analysis of cytotoxic sinapyl alcohol derivatives. Bioorg. Med. Chem. 14:2060-2071.
Crossref

  

 

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

Back to Vol. 11 No. 43
Back to articles
SUBSCRIBE TO RSS
SUBMIT MANUSCRIPT
CONFERENCES