Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Effect of aqueous extract of Ocimum gratissimum on acetaminophen induced renal toxicity in male wistar rats

Okerulu Linda
  • Okerulu Linda
  • Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Nigeria.
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Celestine Ani
  • Celestine Ani
  • Department of Human Physiology, College of Medicine, Enugu State University of Science and Technology, Parklane, Enugu, Nigeria.
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Choice Nworgu
  • Choice Nworgu
  • Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Nigeria.
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Igwe Uzoma
  • Igwe Uzoma
  • Department of Physiology, Faculty of Basic Medical Sciences, Alex Ekwueme Federal University, Ndufu-Alike, Ebonyi State, Nigeria.
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Ugwuishi Emeka
  • Ugwuishi Emeka
  • Department of Human Physiology, College of Medicine, Enugu State University of Science and Technology, Parklane, Enugu, Nigeria.
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Nwachukwu Daniel
  • Nwachukwu Daniel
  • Department of Physiology, College of Medicine, University of Nigeria, Enugu Campus, Nigeria.
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  •  Received: 15 September 2018
  •  Accepted: 04 October 2018
  •  Published: 25 November 2018

References

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Adebolu TT, Salau AO (2005). Antimicrobial activity of leaf extracts of ocimum gratissimum on selected diarrhea causing bacteria in south western Nigeria. African Journal of Biotechnology 4(7):682-684.
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Arhgohoro EM, Anosike EO, Uwakwe AA (2012). Ocimum gratissimum aqueous extractenhances recovery in cisplatin-induced nephrotoxicity in albino Wistar rats. Indian Journal of Drugs and Diseases 1(5):129-142.

 

Egesie UG, Adelaiye AB, Ibu JO, Egesie OJ (2006). Safety and hypoglycemicproperties of aqueous leaf extract of Ocimum gratissimum in STZ-induced diabetic animals". Nigerian Journal of Physiological Science 21(1-2):31-35.

 

Ephrain KD, Salami HA, Osewa TS (2000). Effect of aqueous extract of Ocimum gratissimuj on biochemical parameters in rabbits. African Journal Biomedical Research 3(3):175-179.

 

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Nwangwu SCO, Josiah SJ, Offor CE, Ekhyame EC (2015). Evaluation of the effects of aqueous extracts of Ocimum gratissimum on some kidney function parameters in normal male rats. Global Journal of Pharmacology 9(1):72-76.

 

Oboh G (2008). Antioxidant Potential of ocimum gratissimum and Ocimum canum leaf polyphenols and protective effects on some pro-oxidants induced lipid peroxidation in rat brain. An in vitro study. Anal Journal of Food Technology 3(5):325-334.
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Ofokansi KC, Adikwu MU, Esimone CO, Nwodo NM (2003). Antibacterial activity of the leafextract of Ocimum gratissimum (famlabiatae). Journal of Biological Research and Biotechnology 9(1):35-37.

 

Ogundipe DJ, Akomolafe RO, Sanusi AA, Imafidon CE, Olukiran OS, Oladele AA (2017). Ocimum gratissimum Ameliorates gentamicin-induced kidney injury but decreases creatinine clearance following sub-chronic administration in rats. Journal of Evidence Based Complementary Alternative Medicine 22(4):592-602.
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Ojo OA, Oloyede OI, Olanrewaju OI, Ojo AB, Ajiboye BO, Onikanni SA (2013).Toxicity studies of the crude aqueous leaves extracts of Ocimum gratissimum in albino rats. IOSR Journal of Environmental Science, Toxicology and Food Technology 6:434-439.

 

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Sofowora A (2008). Medicinal plants and traditional medicine in Africa. 3rd Edn. Spectrum Books Limited Ibadan, Nigeria pp. 199-204

 

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