Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Potency of extracts of selected plant species from Mbeere, Embu County-Kenya against Mycobacterium tuberculosis

Sospeter Ngoci Njeru
  • Sospeter Ngoci Njeru
  • 1Department of Medicine, Kisii University, P. O. Box, 408-40200, Kisii, Kenya. 2Stem Cell Aging Research group, Fritz Lipmann Institute (FLI) – Leibniz Institute for Age Research, D-07745, Jena, Germany.
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Meshack Amos Obonyo
  • Meshack Amos Obonyo
  • Department of Biochemistry and Molecular Biology, Egerton University, P.O Box. 536-20155 Egerton, Kenya.
  • Google Scholar


  •  Received: 03 January 2016
  •  Accepted: 19 February 2016
  •  Published: 25 March 2016

References

Abubakar EM (2009). Antibacterial activity of crude extracts of Euphorbia hirta against some bacteria associated with enteric infections. J. Med. Plants Res. 3(7):498-505.

 

Al-Bayati FA, Al-Mola HF (2008). Antibacterial and antifungal activities of different parts of Tribulus terrestris L. growing in Iraq. J. Zhejiang Univ. Sci. 9:154-159.
Crossref

 
 

Antoun MD, Ramos Z, Vazques J, Oquendo I, Proctor GR, Gerena L, Franzblau SG (2001). Evaluation of the flora of Puerto Rico for in vitro antiplasmodial and antimycobacterial activities. Phytother. Res. 15:638-642.
Crossref

 
 

Aworet-Samseny RRR, Souza A, Kpahé F, Konaté K, Datté JY (2011). Dichrostachys cinerea (L.) Wight et Arn (Mimosaceae) hydro-alcoholic extract action on the contractility of tracheal smooth muscle isolated from guinea-pig. BMC Complement. Altern. Med. 11:18.
Crossref

 
 

Ayo RG, Amupitan JO, Zhao Y (2007). Cytotoxicity and anti-microbial studies of 1,6,8-trihydroxy-3-methyl-anthraquinone (Emodin) isolated from the leaves of Cassia nigricans Vahl. Afr. J. Biotechnol. 6:1276-1279.

 
 

Becton Dickinson Company (2007). BBL MGIT Mycobacteria growth indicator Manual. Maryland, USA. P 123.

 
 

Brennan PJ, Draper P (1994). In Tuberculosis: Pathogenesis, protection, and control (ed. Bloom, B. R.) (American Society for Microbiology, Washington DC). pp. 271-284.
Crossref

 
 

Cateni F, Zilic J, Falsone G, Hollan F, Frausin F, Scarcia V (2003). Preliminary biological assay on cerebroside mixture from Euphorbia nicaeensis. Farmaco 58:809817.
Crossref

 
 

Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C, Harris D, Gordon SV, Eiglmeier K, Gas S, Barry CE 3rd, Tekaia F, Badcock K, Basham D, Brown D, Chillingworth T, Connor R, Davies R, Devlin K, Feltwell T, Gentles S, Hamlin N, Holroyd S, Hornsby T, Jagels K, Krogh A, McLean J, Moule S, Murphy L, Oliver K, Osborne J, Quail MA, Rajandream MA, Rogers J, Rutter S, Seeger K, Skelton J, Squares R, Squares S, Sulston JE, Taylor K, Whitehead S, Barrell BG (1998). Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393(6685):537-544.
Crossref

 
 

Cole ST, Telenti A (1995). Drug resistance in Mycobacterium tuberculosis. Eur. Respir. Rev. 8:701S-713S.

 
 

Cowan MM (1999). Plant products as anti-microbial agents. Clin. Microbiol. Rev. 12:564-582.

 
 

Denizot F, Lang R (1986). Rapid colorimetric assay for cell growth and survival. J. Immunol. Meth. 89:271-277.
Crossref

 
 

Earl EA, Altaf M, Murikoli RV, Swift S, O'Toole R (2010). Native New Zealand plants with inhibitory activity towards Mycobacterium tuberculosis. BMC Complement. Altern. Med. 10:10-25.
Crossref

 
 

Edwards PA, Ericsson J (1999). Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway. Annu. Rev. Biochem. 68:157-185.
Crossref

 
 

Glickman MS, Jacobs WR (2001). Microbial pathogenesis review of Mycobacterium tuberculosis: Dawn of a discipline. Cell Press 104:477-485.

 
 

Gupta VK, Shukla C, Bisht GRS, Kumar S, Thakur RL (2010). Detection of anti-tuberculosis activity in some folklore plants by radiometric BACTEC assay. Lett. Appl. Microbiol. 52:33-40.
Crossref

 
 

Harborne JB (1984). Phytochemical methods: A guide to modern techniques of plant analysis, 2nd Edition. Chapman and Hall, New York, USA.
Crossref

 
 

Idu M, Erhabor JO, Efijuemue HM (2010). Documentation on medicinal plants sold in markets in Abeokuta, Nigeria. Trop. J. Pharm. Res. 9:110-118.
Crossref

 
 

Ighodaro OM, Agunbiade SO, Omole JO, Kuti OA (2012). Evaluation of chemical, nutritional, antimicrobial and antioxidant-vitamin profiles of Piliostigma thonningii leaves (Nigeria species). Res. J. Med. Plant 6:537-543.
Crossref

 
 

Irungu BN, Rukanga GM, Mungai GM, Muthaura CN (2007). In vitro antiplasmodial and cytotoxicity activities of 14 medicinal plants from Kenya. S. Afr. J. Bot. 73:204-207.
Crossref

 
 

Kaur GJ, Arora DS (2009). Antibacterial and phytochemical screening of Anethum graveolens, Foeniculum vulgare and Trachyspermum ammi. BMC Complement. Altern. Med. 9:30-41.
Crossref

 
 

Khalil IA (2003). Antimicrobial activity of extracts from leaves, stems and flowers of Euphorbia macroclada against plant pathogenic fungi. J. Phytopathol. 42:245-250.

 
 

Lawn SD, Zumla AI (2011). Tuberculosis. Lancet 378:57-72.
Crossref

 
 

Lawson L, Emenyonu N, Abdurrahman ST, Lawson JO, Uzoewulu GN, Sogaolu OM, Ebisike JN, Parry CM, Yassin MA, Cuevas LE (2013). Comparison of Mycobacterium tuberculosis drug susceptibility using solid and liquid culture in Nigeria. BMC Res. Notes 6:215.
Crossref

 
 

Mann A, Amupitan JO, Oyewale AO, Okogun JI, Kolo I (2007). An ethnobotanical survey of indigenous flora for treating tuberculosis and other respiratory diseases in Niger state, Nigeria. J. Phytomed. Ther. 12:1-12.

 
 

Mariita RM, Ogol CKP, Oguge NO, Okemo PO (2010a). Antitubercular and phytochemical investigation of methanol extracts of medicinal plants used by the Samburu community in Kenya. Trop. J. Pharm. Res. 9:379-385.
Crossref

 
 

Mariita RM, Okemo PO, Orodho JA, Kirimuhuzya C, Otieno JN, Magadula JJ (2010b). Efficacy of 13 medicinal plants used by indigenous communities around lake Victoria, Kenya, against tuberculosis, diarrhoea causing bacteria and Candida albicans. Int. J. Pharm. Technol. 2:771-791.

 
 

Mbaveng AT, Ngameni B, Kuete V, Simo IK, Ambassa P, Roy R, Bezabih M, Etoa F, Ngadjui BT, Abegaz BM, Meyer JJM, Lall N, Beng VP (2008). Anti-microbial activity of the crude extracts and five flavonoids from the twigs of Dorstenia barteri (Moraceae). J. Ethnopharmacol. 116:483-489.
Crossref

 
 

Mohamed LT, El Nur BS, Abdelrahman MN (2010). The Antibacterial, antiviral activities and phytochemical screening of some Sudanese medicinal plants. EurAsia. J. Biosci. 4:8-16.

 
 

Mosmann T (1983). Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. 65:55-63.
Crossref

 
 

Mwitari PG, Ayeka PA, Ondicho J, Matu EN, Bii CC (2013). Antimicrobial activity and probable mechanisms of action of medicinal plants of Kenya: Withania somnifera, Warbugia ugandensis, Prunus africana and Plectrunthus barbatus. PLoS ONE 8(6):e65619.
Crossref

 
 

Ngeny LC, Magiri E, Mutai C, Mwikwabe N, Bii C (2013). Antimicrobial properties and toxicity of Hagenia abyssinica (Bruce) J.F.Gmel, Fuerstia africana T.C.E. Fries, Asparagus racemosus (Willd.) and Ekebergia capensis Sparrm. Afr. J. Pharm. Ther. 2:76-82.

 
 

Ngoci SN, Matasyoh JC, Mwaniki CG, Mwendia CM (2012). Antibacterial activity of methanol root extract of Indigofera lupatana Baker F. Eastern J. Med. 17:11-16.

 
 

Ngoci SN, Mwendia CM, Mwaniki CG (2011). Phytochemical and cytotoxicity testing of Indigofera lupatana Baker F. J. Anim. Plant Sci. 11(1):1364-1373.

 
 

Ngoci SN, Ramadhan M, Ngari SM, Oduor PL (2014). Screening for antimicrobial activity of Cissampelos pareira L. methanol root extract. Eur. J. Med. Plants 4:45-51.
Crossref

 
 

Parekh J, Chanda S (2006). In-vitro antimicrobial activities of extractsof Launaea procumbens Roxb. (Labiateae), Vitis vinifera L. (Vitaceae) and Cyperus rotundus L. (Cyperaceae). Afr. J. Biomed. Res. 9:89-93.

 
 

Rao A, Zhang Y, Muend S, Rao R. (2010). Mechanism of antifungal activity of terpenoid phenols resembles calcium stress and inhibition of the TOR pathway. Antimicrob. Agents Chemother. 54(12):50-62.
Crossref

 
 

Samy RP, Gopalakrishnakone P (2008). Review: Therapeutic potential of plants as anti-microbials for drug discovery. J. Evid. Based Complement. Altern. Med. 7:283-294.
Crossref

 
 

Snider DE Jr, Raviglione M, Kochi A (1994). In Tuberculosis: Pathogenesis, protection, and control (ed. Bloom, BR) (American Society of Microbiology, Washington DC). pp. 2-11.

 
 

Sreevatsan S, Pan X, Stockbauer KE, Connell ND, Kreiswirth BN, Whittam TS, Musser JM (1997). Restricted structural gene polymorphism in the Mycobacterium tuberculosis complex indicates evolutionarily recent global dissemination. Proc. Natl. Acad. Sci. USA 94:9869-9874.
Crossref

 
 

Sripathi SK, Sankari U (2010). Ethnobotanical documentation of a few Medicinal plants in the Agasthiayamalai region of Tirunelveli district, India. Ethnobot. Leaflets 14:173-181.

 
 

Tabuti JRS, Kukunda CB, Waako PJ (2009). Medicinal plants used by traditional medicine practitioners in the treatment of tuberculosis and related ailments in Uganda. J. Ethnopharmacol. 127:130-136.
Crossref

 
 

Tomczykowa M, Tomczyk M, Jakoniuk P, Tryniszewska B (2008). Antimicrobial and antifungal activities of the extracts and essential oils of Bidens tripartite. Folia Histochem. Cytobiol. 46:389-393.
Crossref

 
 

Trombetta D, Castelli F, Sarpietro M, Venuti V, Cristani M, Daniele C, Saija A, Mazzanti G, Bisignano G (2005). Mechanisms of anti-bacterial action of three monoterpenes. Antimicrob. Agents Chemother. 49:2474-2478.
Crossref

 
 

Wheeler PR, Ratledge C (1994). In Tuberculosis: Pathogenesis, protection, and control (ed. Bloom, BR) (American Society of Microbiology, Washington DC). pp. 353-385.
Crossref

 
 

World Health Organization (WHO) (2013). Global tuberculosis report 2015. 

View

 
 

World Health Organization (WHO) (2014). Global Tuberclosis Report. 

View

 
 

‎Yuan E, Liu B, Ning Z, Chen C (2009). Preparative separation of flavonoids in Adinandra nitidaleaves by high-speed counter-current chromatography and their effects on human epidermal carcinoma cancer cells. Food Chem. 115:1158-1163.

 
 

Zaleskis R (2006). Adverse effects of anti-tuberculosis chemotherapy. Eur. Respir. Rev. 47-49.