Additive effects of Capsaicin Oleoresin, Irbesartan and Amlodipine Besylate on the blood pressure of spontaneously hypertensive rats

Oyonumo E. Ntekim; Joanne S. Allard; Julius S. Ngwa; Allan A. Johnson; Chimene Castor; Osi Iyalomhe; Thomas V. Fungwe; Thomas Obisesan; Chinwe C. Ntekim

doi:10.5897/JMPR2016.6123

Journal of
Medicinal Plants Research

Abbreviation: J. Med. Plants Res.
Language: English
ISSN: 1996-0875
DOI: 10.5897/JMPR
Start Year: 2007
Published Articles: 3835

Full Length Research Paper

Additive effects of Capsaicin Oleoresin, Irbesartan and Amlodipine Besylateâ€ on the blood pressure of spontaneously hypertensive rats

Oyonumo E. Ntekim

Oyonumo E. Ntekim
Department of Nutritional Sciences, Howard University, College of Allied Health Sciences, Washington, D.C. 20059, USA.
Search for this author on:
Google Scholar

Joanne S. Allard

Joanne S. Allard
Howard University, College of Medicine, Department of Physiology and Biopysics, Washington, D.C. 20059, USA.
Search for this author on:
Google Scholar

Julius S. Ngwa

Julius S. Ngwa
Division of Cardiovascular Medicine, Howard University, College of Medicine, Washington, D.C. 20059, USA.
Search for this author on:
Google Scholar

Allan A. Johnson

Allan A. Johnson
Department of Nutritional Sciences, Howard University, College of Allied Health Sciences, Washington, D.C. 20059, USA.
Search for this author on:
Google Scholar

Chimene Castor

Chimene Castor
Department of Nutritional Sciences, Howard University, College of Allied Health Sciences, Washington, D.C. 20059, USA.
Search for this author on:
Google Scholar

Osi Iyalomhe

Osi Iyalomhe
Department Internal of Medicine, Howard University Teaching Hospital, Washington, DC 20060, USA.
Search for this author on:
Google Scholar

Thomas V. Fungwe

Thomas V. Fungwe
Department of Nutritional Sciences, Howard University, College of Allied Health Sciences, Washington, D.C. 20059, USA.
Search for this author on:
Google Scholar

Thomas Obisesan

Thomas Obisesan
Department Internal of Medicine, Howard University Teaching Hospital, Washington, DC 20060, USA.
Search for this author on:
Google Scholar

Chinwe C. Ntekim

Chinwe C. Ntekim
University of Maryland Baltimore-Washington Medical Center, Glen Burnie, MD 21061, USA.
Search for this author on:
Google Scholar

Article Number - 9E3665159884
Vol.10(30), pp. 468-478 , August 2016
https://doi.org/10.5897/JMPR2016.6123

Received: 15 April 2016
Accepted: 22 June 2016
Published: 10 August 2016

References

Adrogue HJ, Madias NE (2014). Sodium surfeit and potassium deficit: keys to the pathogenesis of hypertension. J. Am. Soc. Hypertens. 8(3):203-213. Crossref

Bankir L, Fernandes S, Bardoux P, Bouby N, Bichet DG (2005) Vasopressin-V2 receptor stimulation reduces sodium excretion in healthy humans. J. Am. Soc. Nephrol. 16:1920-1928. Crossref

Cunhan AR, Umbelino B, Correia LM, Fritsch M (2012). Magnesium and vascular changes in Hypertension Int. J. Hypertens. 754250.

Chobanian AV, Bakris GL, Black HR (2003). The 7th Report of the Joint National Committee on the Prevention, Detection, Evaluation, and Treatment of High Blood Pressure (2003). U.S. Health and Human Services, National Institutes of Health, National Heart, Lung, and Blood Institute, National High Blood Pressure Education Program 2003 JAMA 289(19):2560-2571.

da Silva A, doCarmi J, Dubinion J, Hall JE (2009). Role of sympathetic nervous system in obesity related hypertension. Curr. Hypertens. Rep. 11:206. Crossref

Grassi G, Seravalle G, Quarti-Trevano F. The "neuroadrenergic hypothesis" in hypertension: current evidence (2010). Exp. Physiol. 95:581-6. Crossref

Hu G, Xu X, Liang X, Yang X, Zhang J, Simayi Z, Chen Y (2013). Associations of plasma atrial natriuretic peptide and electrolyte levels with essential hypertension. Exp. Ther. Med. 5(5):1439-1443.

Huang A, Sun D, Koller A (2000). Shear stress-induced release of prostaglandin H2 in the arterioles of hypertensive rats. Hypertension 35:925-30. Crossref

Ikeda T, Gomi T, Sasaki Y (1994). Effects of swim training on blood pressure, catecholamines and prostaglandins in spontaneously hypertensive rats. Jpn. Heart J. 35:205-11. Crossref

Kanbay M, Bayram Y, Solak Y, Sanders PW (2013). Dietary potassium: a key mediator of the cardiovascular response to dietary sodium chloride. J. Am. Soc. Hypertens. 7:395-400. Crossref

Kotchen TA (2011). Hypertensive vascular disease Harrison's Principle of Internal Medicine, 18th edn. McGraw-Hill, New York. Drug Information Handbook: A Comprehensive Resource for Clinicians and Healthcare Professionals (2013.) 22nd edn. Lexi-Comp, Hudson, OH.

Lim SS, Vos T, Flaxman AD (2012). A comparative risk assessment of burden of disease and injury attributed to 67 risk factors and risk factor clusters in 21 regions, 19902013: a systemic analysis for the Global Burden of Disease Study. Lancet 380:2224-60. Crossref

Mironova E, Chen Y, Pao AC, Roos KP, Kohan DE, Bugaj V, Stockand JD (2015). Activation of ENaC by AVP contributes to the urinary concentrating mechanism and dilution of plasma. Am. J. Physiol. Renal Physiol. 308(3):F237-F243. Crossref

Mulrow PJ (1999). Angiotensin II and aldosterone regulation Regul. Pept. 80:27-30. Crossref

Okeahialam BN, Isamade EL, Ibrahim TM, Anjoorin FI (1998). The effect of lacidipine on patients with mild to moderate hypertension and the effect of a combination of lacidipine and hydrochlorothiazide in the treatment of hypertension uncontrolled after four weeks of lacidipine treatment: an open study. West Afr. J. Med. 17:42-46.

Paczwa P, Budzikowski AS, Szczepanska-Sadowska E (1997). Enhancement of central pressor effect of AVP in SHR and WKY rats by intracranial N (G)-nitro-L-arginine. Brain Res. 748(1-2):51-61. Crossref

Reid IA (1998). The renin-angiotensin system: physiology, pathophysiology, and pharmacology. Adv. Physiol. Educ. 20:S237-45.

Salako BL, Kadiri S, Walker O, Fehintola FA (1998). Evaluation of lacidipine (a calcium blocker) in the treatment of hypertension in black African people: a double-blind comparison with hydrochlorothiazide. Afr. J. Med. Med. Sci. 27(1-2):73-75.