Journal of
Medicinal Plants Research

  • Abbreviation: J. Med. Plants Res.
  • Language: English
  • ISSN: 1996-0875
  • DOI: 10.5897/JMPR
  • Start Year: 2007
  • Published Articles: 3835

Full Length Research Paper

Protective potential of Avena sativa seed mucilaginous extract against hyperlipidemia indicated by improved biomarkers and histopathology

Ibtsam M. Gheith
  • Ibtsam M. Gheith
  • Department of Clinical Laboratory Sciences, Faculty of Applied Medical Sciences, Taibah University, 344 Medinah, Saudi Arabia.
  • Google Scholar
Abubakr M. El-Mahmoudy
  • Abubakr M. El-Mahmoudy
  • Department of Pharmacology, Faculty of Veterinary, Medicine, Benha University 13736 Moshtohor, Egypt.
  • Google Scholar


  •  Received: 14 November 2018
  •  Accepted: 21 December 2018
  •  Published: 10 January 2019

References

Anderson JW, Baird P, Davis RH, Ferreri S, Knudtson M, Koraym A, Waters V, Williams CL (2009). Health benefits of dietary fiber. Nutrition Reviews 67(4):188-205.
Crossref

 

Aries M, Vaissiere C, Ceruti I, Charveron M, Gall Y (1999). Avena rhealba activity in cutaneous wound healing process. In: Proceedings of the Journal of Investigative Dermatology pp. 132-132.

 

Bancroft JD, Gamble M (2008). Theory and practice of histological techniques Elsevier Health Sciences P 725 China.

 

Bauer JD (1982). Clinical laboratory methods Cv Mosby, Portland, ME, USA. P 1235.

 

Bennani-Kabchi N, Kehel L, El Bouayadi F, Fdhil H, Amarti A, Saidi A, Marquie G (2000). New model of atherosclerosis in insulin resistant sand rats: hypercholesterolemia combined with D2 vitamin. Atherosclerosis 150(1):55-61.
Crossref

 

Boyer F, Darne S C, Borrel M, Dupuy P, Gall Y (1998). Anti inflammatory properties of oatmeal extracts using a lauryl sulfate irritation model. Journal of Dermatological Science 16:S217.
Crossref

 

Bratt K, Sunnerheim K, Bryngelsson S, Fagerlund A, Engman L, Andersson RE, Dimberg LH (2003). Avenanthramides in oats (Avena sativa L.) and structure− antioxidant activity relationships. Journal of Agricultural and Food Chemistry 51(3):594-600.
Crossref

 

Capasso F (2003). Phytotherapy: A quick reference to herbal medicine. Springer Science and Business Media pp. 424 Heidelberg, Germany.
Crossref

 

Chabrol E, Castellano A (1961). SPV method for estimation of total serum lipid. Journal of Laboratory and Clinical Medicine 57:300.

 

Crowther MA (2005). Pathogenesis of atherosclerosis. ASH Education Program Book (1):436-441.

 

Csont T, Balogh G, Csonka C, Boros I, Horváth I, Vigh L, Ferdinandy P (2002). Hyperlipidemia induced by high cholesterol diet inhibits heat shock response in rat hearts. Biochemical and Biophysical Research Communications 290(5):1535-1538.
Crossref

 

Czerwiński J, Bartnikowska E, Leontowicz H, Lange E, Leontowicz M, Katrich E, Trakhtenberg S, Gorinstein S (2004). Oat (Avena sativa L.) and amaranth (Amaranthus hypochondriacus) meals positively affect plasma lipid profile in rats fed cholesterol-containing diets. The Journal of Nutritional Biochemistry 15(10):622-629.
Crossref

 

Das S, Mitra K, Mandal M (2016). Sample size calculation: Basic principles. Indian Journal of Anaesthesia 60(9):652.
Crossref

 

Dhillon P, Bhatia A (2008). Hypercholesterolemic and Immunomodulatory Effects of Oat Extracts containing ß-glucan. Research Journal of Immunology 1(1):29-35.
Crossref

 

Diaz M, Lopez F, Hernandez F, Urbina JA (2000). L-Carnitine effects on chemical composition of plasma lipoproteins of rabbits fed with normal and high cholesterol diets. Lipids 35(6):627-632.
Crossref

 

El-Mahmoudy AM, Abdel-Fattah FA, Abd El-Mageid A, Gheith IM (2014). Effect of the growth promotant mannan-oligosaccharide on the lipogram and organ function profile in hyperlipidemic albino rats. American Journal of Phytomedicine and Clinical Therapeutics 2:334-347.

 

El-Mahmoudy AM, Shousha SM, Abdel-Maksoud H, AbouZaid O (2013). Effect of long-term administration of sildenafil on lipid profile and organ functions in hyperlipidemic rats. Acta Bio Medica Atenei Parmensis 84(1):12-22.

 

Friedewald WT, Levy RI, Fredrickson DS (1972). Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clinical Chemistry 18(6):499-502.

 

Griffin H, Whitehead C, Broadbent L (1982). The relationship between plasma triglyceride concentrations and body fat content in male and female broilers-a basis for selection? British Poultry Science 23(1):15-23.
Crossref

 

Harborne J (1973). Phytochemical methods, a guide to modern techniques of plant analysis, JB Harborne. Chapman & Hall. London. GB. p 4-13

 

Jenkins A, Jenkins D, Zdravkovic U, Wursch P, Vuksan V (2002). Depression of the glycemic index by high levels of beta-glucan fiber in two functional foods tested in type 2 diabetes. European Journal of Clinical Nutrition 56 (7):622.
Crossref

 

Karmally W, Montez MG, Palmas W, Martinez W, Branstetter A, Ramakrishnan R, Holleran SF, Haffner SM, Ginsberg HN (2005). Cholesterol-lowering benefits of oat-containing cereal in Hispanic Americans. Journal of the American Dietetic Association 105 (6):967-970.
Crossref

 

Kerckhoffs DA, Hornstra G, Mensink RP (2003). Cholesterol-lowering effect of β-glucan from oat bran in mildly hypercholesterolemic subjects may decrease when β-glucan is incorporated into bread and cookies. American Journal of Clinical Nutrition 78(2):221-227.
Crossref

 

Kumar A, Mazumder A, Saravanan V (2008). Antihyperlipidemic activity of Camellia Sinensis leaves in triton wr-1339 induced Albino rats. Pharmacognosy Magazine 4(13):60.

 

Lipka LJ (2003). Ezetimibe: A First‐in‐Class, novel cholesterol absorption inhibitor. Cardiovascular drug reviews 21(4):293-312.
Crossref

 

Liu L, Zubik L, Collins FW, Marko M, Meydani M (2004). The antiatherogenic potential of oat phenolic compounds. Atherosclerosis 175 (1):39-49.
Crossref

 

Mahley RW, Holcombe K (1977). Alterations of the plasma lipoproteins and apoproteins following cholesterol feeding in the rat. Journal of Lipid Research 18(3):314-324.

 

Maier SM, Turner ND, Lupton JR (2000). Serum lipids in hypercholesterolemic men and women consuming oat bran and amaranth products. Cereal Chemistry 77(3):297-302.
Crossref

 

Maizel J, Burkhardt H, Mitchell H (1964). Avenacin, an antimicrobial substance isolated from Avena sativa. I. Isolation and antimicrobial activity. Biochemistry 3(3):424-426.
Crossref

 

Meiattini F, Prencipe L, Bardelli F, Giannini G, Tarli P (1978). The 4-hydroxybenzoate/4-aminophenazone chromogenic system used in the enzymic determination of serum cholesterol. Clinical Chemistry 24(12):2161-2165.

 

Miraj S, Kiani S (2016). Study of pharmacological effect of Avena sativa: A review. Der Pharmacia Lettre 8(9):137-140.

 

Murray R (1984). Aspartate aminotransferase. Clinical Chemistry. Theory, analysis and correlation. Kaplan LA, Pesce AJ (Ed), CV Mosby Company:, St. Louis, Toronto, Princeton, pp: 1112-1116.

 

Nelson RH (2013). Hyperlipidemia as a risk factor for cardiovascular disease. Primary Care: Clinics in Office Practice 40(1):195-211.
Crossref

 

Nie L, Wise M L, Peterson D M, Meydani M (2006). Avenanthramide, a polyphenol from oats, inhibits vascular smooth muscle cell proliferation and enhances nitric oxide production. Atherosclerosis 186(2):260-266.
Crossref

 

Patel SB (2004). Ezetimibe: a novel cholesterol-lowering agent that highlights novel physiologic pathways. Current Cardiology Reports 6(6):439-442.
Crossref

 

Ramakers JD, Volman JJ, Biörklund M, Önning G, Mensink RP, Plat J (2007). Fecal water from ileostomic patients consuming oat β‐glucan enhances immune responses in enterocytes. Molecular Nutrition and Food Research 51(2):211-220.
Crossref

 

Robitaille J, Fontaine-Bisson B, Couture P, Tchernof A, Vohl M-C (2005). Effect of an oat bran-rich supplement on the metabolic profile of overweight premenopausal women. Annals of Nutrition and Metabolism 49 (3):141-148.
Crossref

 

Ross R (1986). The pathogenesis of atherosclerosis—an update. New England Journal of Medicine 314(8):488-500.
Crossref

 

Ross R, Harker L (1976). Hyperlipidemia and atherosclerosis. Science 193(4258):1094-1100.
Crossref

 

Singh R, De S, Belkheir A (2013). Avena sativa (Oat), a potential neutraceutical and therapeutic agent: an overview. Critical Reviews in Food Science and Nutrition 53 (2):126-144.
Crossref

 

Tabak C, Wijga A H, de Meer G, Janssen NA, Brunekreef B, Smit HA (2006). Diet and asthma in Dutch school children (ISAAC-2). Thorax 61(12):1048-1053.
Crossref

 

Ververidis F, Trantas E, Douglas C, Vollmer G, Kretzschmar G, Panopoulos N (2007). Biotechnology of flavonoids and other phenylpropanoid derived natural products. Part I: Chemical diversity, impacts on plant biology and human health. Biotechnology Journal: Healthcare Nutrition Technology 2(10):1214-1234.
Crossref

 

Xu JG, Tian CR, Hu QP, Luo JY, Wang XD, Tian XD (2009). Dynamic changes in phenolic compounds and antioxidant activity in oats (Avena nuda L.) during steeping and germination. Journal of Agricultural and Food Chemistry 57(21):10392-10398.
Crossref

 

Yost TJ, Froyd KK, Jensen DR, Eckel RH (1995). Change in skeletal muscle lipoprotein lipase activity in response to insulin/glucose in non-insulin-dependent diabetes mellitus. Metabolism-Clinical and Experimental 44(6):786-790.
Crossref

 

Young DS, Pestaner L, Gibberman V (1975). Effects of drugs on clinical laboratory tests (Vol. 4, No. 8). Washington, DC: AACC Press.

 

Zhou M, Panchuk-Voloshina N (1997). A one-step fluorometric method for the continuous measurement of monoamine oxidase activity. Analytical Biochemistry 253 (2):169-174.
Crossref

 

Zulet MA, Barber A, Garcin H, Higueret P, Martinez JA (1999). Alterations in carbohydrate and lipid metabolism induced by a diet rich in coconut oil and cholesterol in a rat model. Journal of the American College of Nutrition 18(1):36-42.
Crossref