Influence of age and staking on the growth and cryptolepine concentration in cultivated roots of Cryptolepis sanguinolenta (Lindl.) Schlt.

J. N. Amissah; D. Osei-Safo; C. M. Asare; B. Missah-Assihene; E. Y. Danquah; I. Addae-Mensah

doi:10.5897/JMPR2015.5793

Journal of
Medicinal Plants Research

Abbreviation: J. Med. Plants Res.
Language: English
ISSN: 1996-0875
DOI: 10.5897/JMPR
Start Year: 2007
Published Articles: 3834

Full Length Research Paper

Influence of age and staking on the growth and cryptolepine concentration in cultivated roots of Cryptolepis sanguinolenta (Lindl.) Schlt.

J. N. Amissah

J. N. Amissah
Crop Science Department, University of Ghana, P. O. Box LG 44, Legon Accra, Ghana.
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D. Osei-Safo

D. Osei-Safo
Chemistry Department, University of Ghana, P. O. Box LG 56, Legon, Accra, Ghana.
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C. M. Asare

C. M. Asare
Plant Genetic Resources Research Institute (PGRRI), P. O. Box 7 Bunso, Ghana.
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B. Missah-Assihene

B. Missah-Assihene
Crop Science Department, University of Ghana, P. O. Box LG 44, Legon Accra, Ghana.
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E. Y. Danquah

E. Y. Danquah
West Africa Centre for Crop Improvement (WACCI), P. O. Box LG 30 Legon, Accra, Ghana.
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I. Addae-Mensah

I. Addae-Mensah
Chemistry Department, University of Ghana, P. O. Box LG 56, Legon, Accra, Ghana.
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Article Number - FCAE99457579
Vol.10(9), pp. 113-121 , March 2016
https://doi.org/10.5897/JMPR2015.5793

Received: 09 March 2015
Accepted: 05 June 2015
Published: 03 March 2016

References

Ansah C, Khan A, Gooderham NJ (2005). In vitro genotoxicity of West African antimalarial herbal Cryptolepis sanguinolenta and its major alkaloid cryptolepine. Toxicology 208(1):141-147. Crossref

Bierer DE, Fort DM, Mendez CD, Luo J, Imbach PA, Dubenko LG, Jolad SD, Gerber RE, Litvac J, Lu Q, Zhang P, Reed MJ, Waldeck N, Bruening RC, Noamesi BK, Hector RF, Carlson TJ, King SR (1998). Ethnobotanical-directed discovery of the antihyperglycaemic properties of cryptolepine: its isolation from Cryptolepis sanguinolenta, synthesis, and invitro and in vivo activities. J. Med. Chem. 41(6):894-901. Crossref

Bugyei KA, Boye GL, Addy ME (2010). Clinical Efficacy of a Tea-Bag Formulation of Cryptolepis Sanguinolenta Root in the Treatment of Acute Uncomplicated Falciparum malaria. Ghana Med. J. 44(1):3-9.

Cimanga K, De Bruyne T, Pieters L, Vlietinck AJ, Turger CA (1997). In vitro and in vivo antiplasmodial activity of cryptolepine and related alkaloids from Cryptolepis sanguinolenta. J. Nat. Prod. 60:688-691. Crossref

Cryptolepine Structure- CSID:74137, View

Cunningham AB (1993). African medicinal plants. Setting priorities at the interface between conservation and primary healthcare. Plant and People Initiative. UNESCO, France. Available at: View

Dwuma-Badu D, Ayim JS, Fiagbe NI, Knapp JE, Schiff PI, Slatkin DJ (1978). Constituents of west African medicinal plants: XX Quindoline from Cryptolepis sanguinolenta. J. Pharm. Sci. 67(3):433-4. Crossref

Harborne JB (1993). Introduction to ecological biochemistry. 4th edition. Academic Press, London.

Jansen PCM, Schmelzer GH (2010). Cryptolepis sanguinolenta (Lindl.) Schltr. In: Schmelzer GH and Gurib-Fakim A (Eds.), Prota 11(2): Medicinal plants/Plantes médicinales 2. [CD-Rom]. PROTA, Wageningen, Netherlands.

Kirby GC, Paine A, Warhurst DC, Noamesi BK, Phillipson JD (1995). In vitro and in vivo antimalarial activity of cryptolepine, a plant-derived indoloquinoline. Phytother. Res. 9:359-363. Crossref

Kurian A, Sankar A (2007). Medicinal Plants, New India Publishing 356.

Li TSC (2000). Medicinal Plants: Culture, Utilization and Phytopharmacology. CRC publishers. P 536.

Luo J, Fort DM, Carlson TJ, Noamesi BK, Nii-Amon-Kotei D, King SR, Tsai J, Quan J, Hobensack C, Lapresca P, Waldeck N, Mendez CD, Jolad SD, Bierer DE, Reaven GM (1998). Cryptolepis sanguinolenta: an ethnobotanical approach to drug discovery and the isolation of a potentially useful new antihyperglycaemic agent. Diabetic Med. 15:367-374. Crossref

Norman JC (1992). Tropical vegetable crops. Arthur Stockwell Ltd, Great Britain.

Ofori DA, Darko BO, Gyimah A, Adam KA, Jimoh SO, Jamnadass R (2012). Ethobotany, Propagation and Conservation of Medicinal Plants in Ghana. Ghana J. For. 28(1):29-38.

Sawer IK, Berry MI, Ford JL (2005). The killing effect of cryptolepine on Staphylococcus aureus. Lett. Apl. Microbiol. 40:24-29. Crossref

Sharaf MHM, Schiff Jr PL, Tackie AN, Phoebe Jr CH, Martin GE (1996). Two new indoloquinoline alkaloids from Cryptolepis sanguinolenta: cryptosanguinolentine and cryptotackieine. J. Heterocycl. Chem. 33:239-243. Crossref

Singh RS, Bhattacharya TK, Ghosh AC (1996). Variability in Yield of Tuber and Diosgenin in Plants Developed by Seed and Single-Node Leaf-Cutting and Vine Staking of Medicinal Yam (Dioscorea-Floribunda). Indian J. Agric. Sci. 66(8):443-445.

Singh RK, Singh JP, Lal SS (2008). Dry Matter Partitioning Relative to Development in High Yielding Indian Potato Cultivars Under Short Day Tropical Conditions. Potato J. 35(3-4):161-166.

Tachie AN, Sharaf MHN, Schiff PL, Boye GL, Crouch RC, Martin GE (1991). Assignment of proton and carbon NMR spectra of the indoquinoline alkaloid cryptolepine. J. Heterocycl. Chem. 28:1429-1435. Crossref

Tackie AN, Boye GL, Sharaf MHM, Schiff PL Jr, Crouch RC, Spitzer TD, Johnson RL, Dunn J, Minick D, Martin GE (1993). Cryptospirolepine, a Unique Spiro-nonacyclic Alkaloid Isolated from Cryptolepis sanguinolenta. J. Nat. Prods. 56(5):653-670. Crossref

Tempesta MS (2010). The Clinical Efficacy of Cryptolepis Sanguinolenta in the treatment of Malaria. Ghana Med. J. 44(1):1-2.

Waller GR, Nowacki E (1978). Alkaloid Biology and Metabolism in Plants. Plenum Press, New York. Available at: Phytochemistry 18(4):707-708.

Willcox M, Bodeker G, Rasoanaivo P, Addae-Kyereme J (2004). Traditional Medicinal Plants and Malaria. CRC Press. P 464.

World Health Orgaanization (WHO) (2012). World Malaria Report 2012 Fact Sheet. Available at: www.who.int/malaria

Wright CW, Phillipson JD, Awe SO, Kirby GC, Warhurst DC, Quertin-Leclerq J, Angenot L (1996). Antimalarial activity of cryptolepine and some other anhydronium bases. Phytother. Res. 10:361-363. Crossref