October 2018

Antiviral effect of the seaweed Osmundaria obtusiloba against the Zika virus

Zika virus (ZIKV), a mosquito-borne member of the family Flaviviridae, is a human pathogen of global significance. Recently, ZIKV, has become a public health problem with increases in numbers of cases and a strong association between ZIKV outbreaks and the spread of cases of Guillain-Barré Syndrome and microcephaly. In this study, the extracts of the seaweed Osmundaria obtusiloba (O. obtusiloba) (native to the...

Author(s): Claudio Cesar Cirne-Santos, Caroline de Souza Barros, , Caio Cesar Richter Nogueira, Leonardo dos Santos Corrêa Amorim, Renata de Mendonça Campos, Norman Arthur Ratcliffe, Valeria Laneuville Teixeira, Davis Fernandes Ferreira and Izabel Christina Nunes de Palmer Paixão  

October 2018

Malaria parasite clearance rate of crude methanol extract of Cryptolepis sanguinolenta in mice infected with chloroquine sensitive strain of Plasmodium berghei

This study aims to determine the malaria parasite clearance rate of crude methanol extract of Cryptolepis sanguinolenta in mice infected with chloroquine sensitive strain of Plasmodium berghei. P. berghei was injected in mice and left for 3 days for establishment. Blood sample collected and diluted with phosphate buffer saline was used for infection. Five (5) groups of animals (mice) were used in this study each...

Author(s): Eze, Chinelo C., Attama, Anthony A., Ibezim, Emmanuel C., Berebon, Dinebari P. and Agbo, Martina C.

October 2018

Chemical composition, oviposition deterrent and larvicidal activities of the wood extracts of Tabebuia avellanedae from the Cerrado of Brazil

Tabebuia avellanedae is an important timber source belonging to the family of Bignoniaceae. The latter is known for its richness in terms of variety of bioactive chemical constituents, and it has been used in folk medicine for treatment of various diseases. The aim of this work was to investigate the chemical composition, oviposition deterrent and larvicidal activities of the wood extracts of T. avellanedae from the...

Author(s): Jaqueline Cibene Moreira Borges, Eder Alves Pereira e Silva, Tarcísio Castro Alves de Barros, Ilsamar Mendes Soares, Sérgio Donizeti Ascêncio, Rodrigo Ribeiro Fidelis and Raimundo Wagner de Souza Aguiar