August 2013
Anti-aggregation effects of thymoquinone against Alzheimer’s β-amyloid in vitro
Beta amyloid peptide (Aβ) aggregation has been identified as one of the major causes of neurodegenerative processes in Alzheimer’s disease (AD). Despite recent improvements in the symptomatic therapy of cholinergic drugs; development of an effective therapeutic approach, that may interfere directly with Aβ aggregation in the central nervous system, is desperately required. Thymoquinone (TQ) is a...
August 2013
Chemical composition of Microstylis wallichii Lindl. from Western Himalaya
Microstylis wallichii Lindl. is a Rasayana and belongs to the “Astverga”. It is an important medicine traditionally known since Vedic period but study on its phytoconstituents is very limited. Metal content and volatile constituents in M. wallichii (family Orchidaceae) collected from Uttarakhand were analyzed by Atomic Absorption Spectrophotometer and GC and GC-MS respectively. Chemical...
August 2013
Aerial parts of Solanum agrarium Sendtn. (Solanaceae) present the flavonoid myricetin 3,7,3’ trimethyl ether and antispasmodic effect on guinea-pig ileum by blockade of voltage-gated calcium channels
Solanum agrarium Sendtn. is popularly known in Northeastern Brazil as "gogóia". Previous work has verified the presence of the flavonoid kaempferol and showed the crude ethanolic extract from aerial parts of S. agrarium (SA‑EtOH) to have non-selective antispasmodic effect on guinea‑pig ileum. The aim was to isolate and identify the special metabolites and to investigate antispasmodic...
August 2013
Ethnobotanical study of medicinal plants of the Ipassa-Makokou Biosphere Reserve, Gabon: Plants used for treating malaria
Malaria remains a major cause of illness and death as well as a contributing factor to poverty in tropical and subtropical regions. Ethnobotanical surveys conducted in the periphery of the Ipassa - Biosphere Reserve (Gabon) allowed to identify 61 plant species used by the Baka pygmies, Fang, Kota and Kwélé ethnic groups for the treatment of malaria. These plants are distributed in 55 genera and 34...
August 2013
Influence of variety and extraction solvent on antibacterial activity of roselle (Hibiscus sabdariffa L.) calyxes
An analysis was done on the antimicrobial activity of calyx extracts from five Hibiscussabdariffa varieties against Salmonella typhimurium and Salmonella choleraesuis. Calyx extracts produced with water, ethanol and methanol were applied to Salmonella cultures. All extracts exhibited antimicrobial activity against both Salmonella serotypes. The antimicrobial effect was...
August 2013
Optimization of extraction and characterization of polysaccharides from medicinal mushroom Ganoderma lucidum using response surface methodology
Submerged fermentation for the production of polysaccharides has received the greatest interest in recent years due to its increased demand as drug. Response surface methodology was employed to optimize the conditions for extraction of polysaccharides fromGanoderma lucidum. Central composite rotatable design was employed to optimize temperature, time, sodium hydroxide (NaOH) concentration and volume of NaOH for...
August 2013
Inhibition of the principal enzymatic and biological effects of the crude venom of Bothrops atrox by plant extracts
This study analyzes the effectiveness of extracts from five plant species used for treating venomous snakebites in the region of Santarém, in central Brazilian Amazonia. The aqueous extracts of Bellucia dichotoma Cogn., Connarus favosus Planch., Aniba fragrans Ducke,Plathymenia reticulata Benth., and Philodendron megalophyllum Schott were prepared by decoction at...
August 2013
Phytochemical screening and effect of ethanol root extract of Microdesmis puberula on some haematological and biochemical parameters in normal male albino Wistar rats
Microdesmis puberula Hook f. ex. Planch (Pandaceae) is one of the understudied medicinal plants whose pharmacological properties are beginning to be elucidated. In the present study, ethanol root extract of M. puberula was used to assess its effects on some biochemical and haematological parameters in male rats. The root extract was administered in graded doses of 200, 400 and 600 mg/kg body weight to...
August 2013
The influence of using Bauhinia forficata Link in glycemic, lipid and toxicological profile in in vivo experimental models: A systematic review
Bauhinia forficata Link, popularly known as ‘cow's paw’, is characterized as a plant species widely used in traditional medicine as hypoglycemiant. Given its high empirical use for therapeutic purposes coupled with the high interest in research with this plant species, this study aimed to perform a systematic review on B. forficata L. seeking for evidence-based information on the influence...
August 2013
Correlation between chemical profiles of black pepper (Piper nigrum L.) var. Panniyur-1 collected from different locations
Bauhinia forficata Link, popularly known as ‘cow's paw’, is characterized as a plant species widely used in traditional medicine as hypoglycemiant. Given its high empirical use for therapeutic purposes coupled with the high interest in research with this plant species, this study aimed to perform a systematic review on B. forficata L. seeking for evidence-based information on the influence...
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