September 2020
Protective effect of piperine from Piper chaba fruits on LPS-induced inflammation in human intestinal cell line
Piper chaba is a flowering vine in the family of piperaceae. It is a spicy plant widely used as food and herbal medicine in the South and Southeast Asian countries. The study evaluated anti-inflammatory and immunomodulatory activities of a major alkaloid extract, piperine, from P. chaba fruits on human colonic epithelial cells. The effects of piperine extract on cell viability, pro-inflammatory cytokine inhibition, and...
September 2020
Larvicidal activity of Juniperus procera extract against anopheles mosquito in in vitro, North Western Ethiopia
Mosquitoes are the major health threat as they transmit plasmodium parasites that cause malaria. Since mosquitoes developed resistances towards insecticides, investigators are searching for alternative control measures. Bioactive plant chemicals have been identified to serve as a defense mechanism against insects’ larvae. Therefore, the aim of the study was to evaluate larvicidal activities of Juniperus procera...
September 2020
Screening open source traditional Chinese medicine extracts for growth-inhibiting properties towards Acinetobacter baumannii
Infections caused by Acinetobacter baumannii and other pathogenic bacteria are a worldwide concern due to their increasingly prevalent multidrug resistance. World leaders and health organizations across the globe have voiced their concerns over antibiotic resistance and the critical need for the development of novel antibiotics. Although the number of new antibiotic drugs entering the marketplace in recent years has...
September 2020
Antibacterial, total phenols, antioxidant, and fatty acids of the lyophilized body fat of Podocnemis expansa (Schweigger, 1812) from farm in Acre State, Brazil
Podocnemis expansa (Podocnemididae) is a chelonian of suborder Pleurodira and is popularly known as Amazon turtle. The animal’s body fat was removed from the farm in Xapuri city in Acre State, Brazil. The fat was lyophilized and the oil was extracted by the Soxhlet method using hexane, as a solvent. The fatty acids majority, identified and quantified by gas chromatography-flame ionization detector, were:...
September 2020
Ethnobotanical survey of medicinal plants commonly used in snakebites in North Western Nigeria
The incidence of snake bite in rural West Africa is reportedly high with an 11–17% mortality rate. Nigeria has one third of the cases for snake bite cases in this region.Thus, most tribes in North-western part of Nigeria depend on medicinal plants for snakebites. However, it appears that a gap exists on documentation of these plants especially tropical flora used in the management of snake bite. This led to...
September 2020
In vitro antibacterial activity of Psidium guajava (Guava) leaves extract on carbapenem-resistant Klebsiella pneumoniae causing multi-drug resistant systemic infections
Systemic bacterial infections affect almost all part of the human body systems leading to infections such as urinary tract infections, septicemia, meningitis, pneumonia, peritonitis and gastritis. Carbapenems have been used as drug of choice in the treatment of systemic infections. Studies have indicated that Enterobacteriaceae are producing enzymes such as carbapenemases, which inactivate carbapenems. There ...
September 2020
Medicinal plants used against malaria by traditional therapists in malaria endemic areas of the Ségou region, Mali
West Africa is one of the regions in Africa with the highest levels of malaria transmission a descriptive study was carried out to inventorise the medicinal plants traditionally used against malaria by traditional therapists in five malaria endemic areas of the Ségou region, in Mali. Sixty-five traditional therapists were randomly selected to be part of the study. Questions were posed using semi-structured...
September 2020
Chemo preventive effect of methanol extract of Anacardium occidentale nut shell on ultra-violet radiation induced skin damage
Anacardium occidentale nut shell liquid has been used for decades especially by natives of South America, Asia and Africa in the treatment of topical skin diseases, abrasion and cancerous ulcers amongst others. Chronic exposure to sunlight can lead to skin damages including erythema, edema, hyperplasia, formation of sunburn cells, photo-aging, suppression of the immune system and skin cancer. This study was aimed at...
September 2020
Ethnobotanical study of plants used against onchocerciasis in the far north region of Cameroon
Despite the multitude of studies which have shown the use of medicinal plants in the management of parasitic diseases, little data was available on the plants used against onchocerciasis. Ethnobotanical surveys were carried out among traditional healers in the Far North region of Cameroon. Studies were conducted from July 2017 to May 2018 through direct interviews using a semi-structured questionnaire taking into...
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