September 2013
In vitro 5-Lipoxygenase inhibition of polyphenolic antioxidants from undomesticated plants of South Africa
Aqueous and methanolic extracts of 18 leafy vegetables from South Africa were investigated for their free radical scavenging activity, total phenolic content and anti-inflammatory properties. Amaranthus dubius, Amaranthus hybridus, Amaranthus spinosus, Asystasia gangetica, Bidens pilosa, Centella asiatica, Ceratotheca triloba, Chenopodium album, Cleome monophylla, Emex australis, Galinsoga parviflora, Justicia...
September 2013
Analgesic, anti-inflammatory, antipyretic and anti-plasmodial effects of the methanolic extract of Crossopteryx febrifuga
Preparations of Crossopteryx febrifuga have been used in traditional medicine for treatment of pain and malaria for many years and their efficacies are widely acclaimed among the Hausa communities of northern Nigeria. The methanolic extract of C. febrifuga was evaluated for analgesic, anti-inflammatory, antipyretic and anti-plasmodial activities of in rodents. The extract significantly diminished...
September 2013
Analgesic, anti-inflammatory and antipyretic activities from flavonoid fractions of Chromolaena odorata
The ethanolic extract of Chromolaena odorata was fractionated with solvent-solvent extraction technique using the following solvents successively, n-hexane, dichloromethane, ethyl acetate, n-butanol and water. The fractions were evaluated for analgesic, anti-inflammatory and antipyretic activities using standard experimental models which includes; hot plate and formalin paw licking tests for analgesic...
September 2013
Diversity and conservation of medicinal plants in the Bomaa community of the Brong Ahafo region, Ghana
Patrick Addo-Fordjour*, Alexander Kofi Anning, Ebenezer Jeremiah Durosimi Belford and Dorcas Akonnor
September 2013
Isolation and characterization of 2, 3, 8-tri-me ether ellagic acid from the stem bark of Irvingia gabonensis (Baill)
The stem bark of Irvingia gabonensis used variously in ethno medicinal treatments in some parts of Nigeria was studied. A silica gel column chromatography of the methanol extract (using only chloroform) eluted a pale yellow crystalline substance identified by means of spectral analyses as 2,3,8-Tri-Me ether ellagic acid. Key words: Irvingia gabonensis, 2, 3, 8-Tri-Me ether ellagic acid,...
September 2013
Rosmarinic acid biosynthesis in callus and cell cultures of Agastache rugosa Kuntze
Callus and cell suspension cultures of Agastache rugosa were established to investigate the production of rosmarinic acid in vitro. For callus induction 2,4-D treatment was more effective than that of NAA. The best callus induction rate (92%) and callus growth A. rugosa were obtained in MS medium containing 2 mg/l 2, 4-D. In cell suspension culture of A. rugosa, the maximum growth (7.7 g/l)...
September 2013
In vitro propagation of Crotalaria verrucosa L. an important ethnobotanical plant
An efficient and reproducible procedure for the large scale propagation ofCrotalaria verrucosa, an important ethno botanical herb is described. Multiple shoots were produced from cotyledonary nodes of 15 days old aseptic seedlings on Murashige and Skoog (MS) medium supplemented with thidiazuron (TDZ) or benzyladenine (BA). Highest number (6.0) of shoots per cotyledonary node was recorded on MS medium with 0.1 μM...
September 2013
Anti-diabetic activity of Syzygium cumini and its isolated compound against streptozotocin-induced diabetic rats
Syzygium cumini (Myrtaceae) is widely used traditional system of medicine to treat diabetes in India. The present study was carried out to isolate and identify the putative antidiabetic compound from the S. cumini [SC] seed. A compound, mycaminose was isolated from SC seed extract. The isolated compound mycaminose (50 mg/kg) and ethyl acetate [EA] and methanol [ME] extracted compounds of S....
September 2013
Increase in flavonoids content in red onion peel by mechanical shredding
Quercetin, a bioflavonoid extracted from red onion peel, has a marked inhibitory activity against phosphodiesterase 5A. Mechanical shredding of red onion peel increased its total flavonoid content two fold compared to control. Change in individual flavonoid content was studied using HPLC. Quercetin 4'-O-β-glucopyranoside showed the highest increase in content after shredding with slight change in quercetin...
September 2013
Antioxidant property of selected Ocimum species and their secondary metabolite content
In this study, chemical composition and antioxidative properties of eight selected Ocimum species (Ocimum gratissimum, Ocimum americanum, Ocimum minimum, Ocimum citriodorum, Ocimum kilimandscharicum, Ocimum grandiflorum, Ocimum lamiifolium, and Ocimum selloi) was investigated. Leaves of these plants were extracted using methanol. The quantitative analysis of phenolic constituents was determined using...
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