Journal of
Pharmacognosy and Phytotherapy

  • Abbreviation: J. Pharmacognosy Phytother.
  • Language: English
  • ISSN: 2141-2502
  • DOI: 10.5897/JPP
  • Start Year: 2009
  • Published Articles: 223

Full Length Research Paper

Phytochemical properties and effect of aqueous extract of Jatropha caucus root bark on some bacterial isolates

M. S. Auwal1*, A. L. Fatima2, A. Shuaibu3, A. M. Ismaila4, A. S. Kyari1, A. B. Thaluvwa5 and A. B. Njobdi6
1Department of Veterinary Physiology, Pharmacology and Biochemistry, University of Maiduguri, Borno State, Nigeria. 2Department of Veterinary Microbiology and Parasitology, University of Maiduguri, Borno State Nigeria. 3Department of Human Anatomy, College of Medical Sciences, University of Maiduguri, Borno State, Nigeria. 4Department of Veterinary Medicine, University of Maiduguri, Borno State Nigeria. 5Department of Veterinary Public Health and Preventive Medicine, University of Maiduguri, Borno State, Nigeria. 6Department of Animal Health, College of Agriculture, Jalingo, Taraba State, Nigeria.
Email: [email protected]

  •  Accepted: 25 March 2013
  •  Published: 31 August 2013

Abstract

Phytochemical properties and effect of aqueous extract of Jatropha caucus root bark on some bacteria isolates was investigated. The root bark extract revealed the presence of carbohydrates, alkaloids, flavonoids, saponins, cardiac glycosides and terpenes/steroids. The extract applied in graded concentrations of 200, 400 and 600 mg/ml inhibited the multiplication of Staphylococcus aureus, Streptococcus pyogenes, Bacillus subtilis,Corynebacterium pyogenesCandida albicans, Pseudomonas aeroginosa, Klebsiella pneumoniae, Salmonella typhi, Escherichia coli and Proteus mirabilis. Conclusively, the root bark extract of this plant has exhibited good antibacterial activity especially on organisms such as B. subtilisC. albicansS. pyogenesProteus species, E. coli and S. typhi  that are incriminated in causing diseases such as anthrax, reproductive tract infection, skin infection and various gastrointestinal disorders.

 

Key words: Jatropha curcas, phytochemical properties, in vitro antibacterial activity, aqueous root bark extract.