Journal of
Pharmacognosy and Phytotherapy

  • Abbreviation: J. Pharmacognosy Phytother.
  • Language: English
  • ISSN: 2141-2502
  • DOI: 10.5897/JPP
  • Start Year: 2009
  • Published Articles: 223

Full Length Research Paper

Evaluation of anti-acne activity of hydroalcoholic extract of Punica granatum Linn.

Revan S. Karodi1*, Mahendrakumar C. B. 2 and Kiran Bhise3
1Pad. Dr. D.Y.Patil College of Pharmacy, Akurdi, Pune, Maharashtra – 411044. India. 2St. Mary College of Pharmacy, Secunderabad, Andhra Pradesh – 500085, India. 3MCE Socy’s Allana College of Pharmacy, Camp, Pune, Maharashtra- 411001, India.
Email: [email protected]

  •  Accepted: 29 July 2013
  •  Published: 30 September 2013


Nature always stands as a golden mark to exemplify the outstanding phenomena of symbiosis. Acne vulgaris is an extremely common disorder affecting many adolescents and adults throughout their lifetimes. The pathogenesis of acne is multifactorial and is thought to involve excess sebum, follicular hyperkeratinization, bacterial colonization, and inflammation. Pomegranate, Punica granatum Linn. (Punicaceae) is an ancient, mystical, unique fruit used in several systems of medicine for a variety of ailments. The synergistic action of the pomegranate constituents appears to be superior to that of single constituents. The current research was focused on evaluation of anti-acne activity ofPunica extract followed by its biological screening. The fingerprinting and spectroscopic analysis of the extract was determined. The attempt was made to investigate the extract ofP. granatum for the said activity with the goal of elucidating the active potential compounds.


Key wordsPunica granatum, broth dilution, cup plate method, high performance thin layer chromatography.