Garcinia hanburyi belongs to the family Clusiaceae. The whole plant was dried, extracted to obtain Xanthone rich extract. Phytochemical studies of extract showed the presence of Phenols, Alkaloids, steroids, resins and saponins. The natural sources such as a plants are an abundant source having various medicinal properties. In the present study, Garcinia hanburyi has been selected to test for the Anti-inflammatory activity by Proteinase inhibitory activity, Membrane stabilization, Albumin denaturation assay at various concentrations. The results showed that the extract from Garcinia hanburyi at a concentration from 100-500 µg/ml protects protein denaturation. Significant proteinase inhibitory activity was seen at the concentration of 400 µg/ml and 500 µg/ml. Heat induced hemolysis of erythrocyte was considerably inhibited at the concentrations of 400 µg/ml. The results which are obtained from the present study shows that the extract of Garcinia hanburyi can be a promising resource of anti-inflammatory agents.

Keywords: Garcinia hanburyi, Xanthones, Anti-Inflammatory, Xanthones, Membrane stabilization, HRBC