Journal of
Pharmacognosy and Phytotherapy

  • Abbreviation: J. Pharmacognosy Phytother.
  • Language: English
  • ISSN: 2141-2502
  • DOI: 10.5897/JPP
  • Start Year: 2009
  • Published Articles: 234

Full Length Research Paper

Phytochemical and zootechnical studies of Physalis peruviana L. leaves exposured to streptozotocin-induced diabetic rats

C. N. Fokunang
  • C. N. Fokunang
  • Department of Pharmacotoxicology and Pharmacokinetics, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, P. O. Box 1634, Yaoundé Cameroon.
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F. K. Mushagalusa
  • F. K. Mushagalusa
  • Department of Pharmacy, Faculty of Medicine and Pharmacy, Official University of Bukavu, P. O. Box 570 Bukavu, Democratic Republic of Congo.
  • Google Scholar
E. Tembe-Fokunang
  • E. Tembe-Fokunang
  • Department of Pharmacotoxicology and Pharmacokinetics, Faculty of Medicine and Biomedical Sciences, University of Yaoundé I, P. O. Box 1634, Yaoundé Cameroon.
  • Google Scholar
J. Ngoupayo
  • J. Ngoupayo
  • Department of Pharmacognosy and Pharmaceutical chemistry, University of Bamenda, Cameroon.
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B. Ngameni
  • B. Ngameni
  • Department of Medical Laboratory Sciences, University of Bamenda, Cameroon.
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L. N. Njinkio
  • L. N. Njinkio
  • Department of Medical Laboratory Sciences, University of Bamenda, Cameroon.
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J. N. Kadima
  • J. N. Kadima
  • Department of Pharmacology, School of Medicine and Health Sciences, University of Rwanda, Rwanda.
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F. A. Kechia
  • F. A. Kechia
  • Department of Medical Laboratory Sciences, University of Bamenda, Cameroon.
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B. Atogho-Tiedeu
  • B. Atogho-Tiedeu
  • Department of Biochemistry, Faculty of Sciences; University of Yaounde I, P. O. Box 812 Yaounde, Cameroon.
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W. F. Mbacham
  • W. F. Mbacham
  • Department of Pharmacology, School of Medicine and Health Sciences, University of Rwanda, Rwanda.
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B. T. Ngadjui
  • B. T. Ngadjui
  • Department of Pharmacognosy and Pharmaceutical chemistry, University of Bamenda, Cameroon.
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  •  Received: 02 August 2016
  •  Accepted: 15 February 2017
  •  Published: 31 August 2017

References

Abdelmoaty MA, Ibrahim MA, Ahmed NS, Abdelaziz MA (2010). Confirmatory studies on the antioxidant and antidiabetic effect of quercetin in rats. Indian J. Clin. Biochem. 25(2):188-192.
Crossref

 

Ahmed LA (2014). Renoprotective Effect of Egyptian Cape Gooseberry Fruit (Physalis peruviana L.) against Acute Renal Injury in Rats. Sci. World J. Article ID 273870, 7 
Crossref

 

Akbarzadeh A, Norouzian D, Mehrabi MR, Jamshidi SH, Farhangi A, Verdi AA, Mofidian SMA, Rad BL (2007). Induction of diabetes by streptozotocin in rats. Indian J. Clin. Biochem. 22(2):60-64.
Crossref

 

Anderson G, Woodend D (2003). Effect of glycemic carbohydrate on short term satiety and food intake. Nutr. Rev. 61(Supl 5):S17-S26.
Crossref

 

Anthikat RNR, Michael A, Vageesh S, Balamurugan R, Ignacimuthu S (2014). The effect of Areca catechu L., extract on streptozotocin Induced hyperglycaemia in wistar rats. Int. J. Pharm. Bio. Sci. 5(4):316-321.

 

Arika WM, Abdirahman YA, Mawia MM, Wambua KF, Nyamai DM (2015). Hypoglycemic Effect of Lippia javanica in Alloxan Induced Diabetic Mice. J. Diabetes Metab. 6:624.

 

Arika WM, Ogola PE, Nyamai DW, Mawia AM, Wambua FK, Kiboi NG, Wambani JR, Njagi SM, Rachuonyo HO, Emmah KO, Lagat RC, Muruthi CW, Abdirahman YA, Agyirifo DS, Ouko RO, Ngugi MP, Njagi, ENM (2016). Mineral Elements Content of Selected Kenyan Antidiabetic Medicinal Plants. Adv. Tech. Biol. Med. 4(1):160.

 

Armelle MT, Ngameni B, Kuete V, Ingrid SK, Ambassa P, Roy R, Bezabih M, Xavier EF, Bonaventure NT, Berhanu AM, Marion MJJ, Namrita L, Veronique PB (2008). Antimicrobial activity of the crude extracts and five flavonoids from the twigs of Dorstenia barteri (Moraceae). J. Ethnopharmacol. 116:483-489.
Crossref

 

Babu NR (2016). Studies on the evaluation of antidiabetic and antioxidant activities using some selected medicinal plants. Int. J. Herbal Med. 4(2):21-24.

 

Çakir Ö, Pekmez M, Çepni E, Candar B, Fidan K (2014). Evaluation of biological activities of Physalis peruviana ethanol extracts and expression of Bcl-2 genes in HeLa cells. Food Sci. Technol. Campinas 34(2):422-430.
Crossref

 

Chang LC, Sang-ngern M, Pezzuto JM (2016). Poha Berry (Physalis peruviana) with Potential Anti-inflammatory and Cancer Prevention Activities. Haw J. Med. Publ. Health 75 (11):353-359.

 

Chikezie PC, Ojiako OA, Nwufo KC (2015). Overview of Anti-Diabetic Medicinal Plants: The Nigerian Research Experience. J. Diabetes Metab. 6:546.
Crossref

 

Deeni Y, Sadiq N (2002). Antibacterial properties and phytochemical constituents of the leaves of African mistletoe (Tapinanthus dodeneifolius (DC) Danser) (Loranthaceae): and ethno medicinal plants of Hausaland, Northern Nigeria. J. Ethnopharmacol. 83:463-480.
Crossref

 

Ekramul IM, Naznin KA, Ekramul HM (2002). In vitro antibacterial activity of the extracts and glycoside from Sida rhombilfolia Linn. J. Med. Sci. 2(3):134-136.
Crossref

 

Gautam SK, Dwivedi DH, Kumar P (2015). Preliminary studies on the bioactive phytochemicals in extract of Cape gooseberry (Physalis Peruviana L.) fruits and their Products. JPP 3(5):93-95.

 

Gutierrez RMP, Ahuatzi DM, Horcacitas MDC, Baez EG, Victoria TC, Mota-Flores JM (2014). Ameliorative Effect of Hexane Extract of Phalaris canariensis on High Fat Diet-Induced Obese and Streptozotocin-Induced Diabetic Mice. eCAM. 

 

Hafez DA, El-safty SMS, Al-shammari AM (2011). Therapeutic effect of Physalis consumption on liver necrosis in experimental rats. Res. J. Spec. Educ. 2(23):1368-1383.

 

Higaki R, Chang LC, Inouye DK, Sang-ngern M (2016). Antibacterial Activity of Extracts from Physalis peruviana (Poha Berry). J. Health Disp. Res. Pract. 9(1):57-58.

 

Joshi K, Joshi I (2015). Nutritional composition and biological activities of rasbhari: An overview. Int. J. Recent Sci. Res. 6(11):7508-7512.

 

Jothi MA, Kumar BSV, Parameswari CS, Vincent S, Sivasubramanian S (2015). Antidiabetic activity of Cinnamomum macrocarpum Hook.f. leaves on alloxan-induced diabetic swiss albino mice. Int. J. Plant. Anim. Env. Sci. 5(3):16-19.

 

Jouzier E (2005). Solanacées médicinales et philatélie. Bull. Soc. Pharm. Bordeaux. 144:311-332.

 

Kasali FM, Kadima NJ, Mpiana PT, Ngbolua JPK, Tshibangu DS (2013a). Assessment of antidiabetic activity and acute toxicity of leaf extracts from Physalis peruviana (L.) in guinea-pig. Asian Pac J. Trop. Biomed. 3(11):885-890.
Crossref

 

Kasali FM, Mahano AO, Bwironde FM, Amani AC, Mangambu JD, Nyakabwa DS, Wimba LK, Tshibangu DST, Ngbolua KN, Kambale JK, Mpiana PT (2013b). Ethnopharmacological survey of plants used against diabetes in Bukavu city (D.R. Congo). J. Ethno. Trad. Med. 119:538-546.

 

Khathi A, Serumula MR, Myburg RB, Heerden FRV, Musabayane TC (2013). Effects of Syzygium aromaticum-Derived Triterpenes on Postprandial Blood Glucose in Streptozotocin-Induced Diabetic Rats Following Carbohydrate Challenge. Plos One. 8(11).
Crossref

 

Kumar S, Kumar V, Prakash O (2011). Antidiabetic and antihyperlipidemic effects of Dillenia indica (L.) leaves extract. Br. J. Pharm. Sci. 47(2):374-378.
Crossref

 

Lashin II, Elhaw MH (2016). Evaluation of Secondary Metabolites in Callus and Tissues of Physalis peruvianna. Int. J. Mod. Bot. 6(1):10-17.

 

Li HB, Cheng KW, Wong CC, Fan KW, Chen F, Tian Y (2007). Evaluation of antioxidant capacity and total phenolic content of different fraction of selected microalgae. Food Chem. 102:771-776.
Crossref

 

Momeni J, Djoulde RD, Akam MT, Kimbu SF (2005). Chemical constituents and antibacterial activities of the stem bark extracts of Ricinodendron heudelotii (Euphorbiaceae). Indian J. Pharm. Sci. 67:386-399.

 

Ngueguim FT, Esse EC, Dzeufiet PDD, Gounoue RK, Bilanda DC, Kamtchouing P, Dimo T (2016). Oxidised palm oil and sucrose induced hyperglycemia in normal rats: effects of Sclerocarya birrea stem barks aqueous extract. BMC Complement Altern. Med. 16:47.
Crossref

 

Noumi E, Yomi A (2001). Medicinal plants used for intestinal diseases in Mbalmayo Region, Central Province, Cameroon. Fitoterapia 72:246-254.
Crossref

 

Ofusori DA, Komolafe OA, Adewole OS, Obuotor EM, Fakunle JB, Ayoka AO (2012). Effect of ethanolic leaf extract of Croton zambesicus (Müll. Arg.) on lipid profile in streptozotocin-induced diabetic rats. Diabetol. Croatica 41(2):69-76.

 

Organisation of Economic Co-operation and Development (OECD) (2001). The OECD guideline for testing of chemical: 420 Acute Oral Toxicity. OECD, Paris. pp. 1-14.

 

Ozkan G, Kamiloglu S, Ozdal T, Boyacioglu D, Capanoglu E (2016). Potential Use of Turkish Medicinal Plants in the Treatment of Various Diseases. Molecules 21:257.
Crossref

 

Patil MB (2016). Anti-Diabetic Activity of Some Medicinal Plants. Ind. J. Appl. Res. 6(1):641-642.

 

Saini S, Sharma S (2013). Antidiabetic effect of Helianthus annuus L., seeds ethanolic extract in streptozotocin- nicotinamide induced type 2 diabetes mellitus. Int. J. Pharm. Pharm. Sci. 5(1):382-387.

 

Sathyadevi M, Suchithra ER, Subramanian S (2014). Physalis peruviana Linn. fruit extract improves insulin sensitivity and ameliorates hyperglycemia in high-fat diet low dose STZ-induced type 2 diabetic rats. J. Pharm. Res. 8(4):625-632.

 

Savithramma N, Rao ML, Suhrulatha D (2011). Screening of medicinal plants for secondary metabolites. MEJSR. 8:579-584.

 

Sharma N, Bano A, Dhaliwal HS, Sharma V (2015). Perspectives and possibilities of indian species of genus (Physalis peruviana L) - a comprehensive review. Eur. J. Pharm. Med. Res. 2(2):326-353.

 

Singab AN, Youssef FS, Ashour ML (2014). Medicinal Plants with Potential Antidiabetic Activity and their Assessment. Med. Aromat Plants 3:151.

 

Tadjeddine AL, Kambouche N, Medjdoub H, Meddah B, Dicko A, Saidi S, Derdour A (2013). Antidiabetic effect of Anacyclus valentinus L. aqueous extract in normoglycemic and streptozotocin induced-diabetic rats. Am. J. Phytomed. Clin. Ther. 1(5):424-431.

 

Tsague MV, Fokunang NC, Tembe AE, Mvondo AM, Afane EA, Oben EJ, Ngadjui TB, Ntchapda F, Sokeng DS, Nyangono BCF, Dimo T, Minkande JZ ((2016). Hydroethanolic Extract of Eribroma oblongum (Malvaceae) Stem Bark Prevents Hypertension, Oxidative Stress and Dyslipidemia in L-NAME Induced Hypertension in Wistar Rats. J. Dis. Med. Plants 2(4):43-50.

 

World Health Organization (WHO) (2002). Stratégie de l'OMS pour la médecine traditionnelle pour 2002-2005. WHO/EDM/TRM/2002. Genève: OMS: P 65.

 

Xu WX, Chen JC, Liu JQ, Zhou L, Wang YF, Qiu MH (2013). Three new physalins from Physalis alkekengi var. franchetii. Nat. Prod. Bioprospect. 3:103-106.
Crossref

 

Ziane N, Dahamna S, Aouachria S, Khanouf S, Harzallah D (2015). Pistacia atlantica, nouvelle substance utilisée contre le diabète associé au stress oxydant. Diabet. Metab. 41(1):46-47.
Crossref