Journal of
Pharmacognosy and Phytotherapy

  • Abbreviation: J. Pharmacognosy Phytother.
  • Language: English
  • ISSN: 2141-2502
  • DOI: 10.5897/JPP
  • Start Year: 2009
  • Published Articles: 205

Table of Content: July 2013; 5(7)

July 2013

Evaluation of retinoblastoma (Rb) and protein-53 (p53) gene expression levels in breast cancer cell lines (MCF-7) induced with some selected cytotoxic plants

Many Nigerian plants have been hypothesized to have anticancer potentials. However, not many of them have been subjected to acceptable scientific evaluation for their potential anticancer effects. In this study, six of such plants were selected to evaluate the effects of their crude, hexane, chloroform, ethylacetate, detanninfied and tannin fractions for brine shrimp lethality assay and the most cytotoxic fractions of...

Author(s): Samuel Titilola Aderonke, James Ayorinde Babatunde, Oshodi Temitope Adesola, Odii Uchennaya Okereke, Chidume Innocent, Makinde Oluwaseun Elisha, Oguntoye Lanre Abolaji and Magbagbeola Olubunmi Abiola

July 2013

Pharmacognostic and hypoglycemic studies of Achyranthus aspera L.

In the present study, the ethanolic extract of Achyranthus aspera L. Leaves (EEA) were investigated for their pharmacognostic characteristics and hypoglycemic effects. The pharmacognosy of the plant was carried out using microscopic and macroscopic tools. Macroscopic studies revealed that the leaves were cauline, ramel, opposite, exstipulate, simple, sub-sessile, ovate, entire, acute, unicostate, reticulate,...

Author(s): Ishtiaq Ahmad, Muhammad Ibrar, Barkatullah, Naveed Muhammad, Zahir Muhammad and Niaz Ali

July 2013

Nitric oxide-dependent vasodilation and intracellular Ca2+ concentration increase induced by 6,8-dihydroxy-4’-methoxyflavone in rat aorta

In this study, we attempted to evaluate the role of endothelium-derived hyperpolarizing factor (EDHF) in the vasorelaxant response induced by 6,8-Dihydroxy-4’-methoxyflavone (DMF) in isolated rat aorta rings by using functional and biochemical approaches. Thoracic aortic rings were isolated and suspended in organ baths, and the effects of DMF were studied by means of isometric tension recording...

Author(s): Fidèle Ntchapda, Emmanuel Talla, Bonaventure Christian Obono, Bernard Dabolé, Daniele Guido, Francesco Moccia, Franco Tanzi, Joseph Mbafor Tanyiand Théophile Dimo