July 2013
Evaluation of retinoblastoma (Rb) and protein-53 (p53) gene expression levels in breast cancer cell lines (MCF-7) induced with some selected cytotoxic plants
Many Nigerian plants have been hypothesized to have anticancer potentials. However, not many of them have been subjected to acceptable scientific evaluation for their potential anticancer effects. In this study, six of such plants were selected to evaluate the effects of their crude, hexane, chloroform, ethylacetate, detanninfied and tannin fractions for brine shrimp lethality assay and the most cytotoxic fractions of...
July 2013
Pharmacognostic and hypoglycemic studies of Achyranthus aspera L.
In the present study, the ethanolic extract of Achyranthus aspera L. Leaves (EEA) were investigated for their pharmacognostic characteristics and hypoglycemic effects. The pharmacognosy of the plant was carried out using microscopic and macroscopic tools. Macroscopic studies revealed that the leaves were cauline, ramel, opposite, exstipulate, simple, sub-sessile, ovate, entire, acute, unicostate, reticulate,...
July 2013
Nitric oxide-dependent vasodilation and intracellular Ca2+ concentration increase induced by 6,8-dihydroxy-4’-methoxyflavone in rat aorta
In this study, we attempted to evaluate the role of endothelium-derived hyperpolarizing factor (EDHF) in the vasorelaxant response induced by 6,8-Dihydroxy-4’-methoxyflavone (DMF) in isolated rat aorta rings by using functional and biochemical approaches. Thoracic aortic rings were isolated and suspended in organ baths, and the effects of DMF were studied by means of isometric tension recording...
Advertisement
Advertisement
