Journal of
Toxicology and Environmental Health Sciences

  • Abbreviation: J. Toxicol. Environ. Health Sci.
  • Language: English
  • ISSN: 2006-9820
  • DOI: 10.5897/JTEHS
  • Start Year: 2009
  • Published Articles: 194

Full Length Research Paper

Sub-lethal effect of cypermethrin on acetylcholinesterase (AChE) activity and acetylcholine (Ach) content in selected tissues of Channa striatus (Bloch.)

Osman Ahmed
  • Osman Ahmed
  • Department of Zoology, Osmania College (UG & PG), Kurnool-518 004, A.P., India.
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S. A. Mastan*
  • S. A. Mastan*
  • Matrix-ANU Advanced Aquaculture Research Centre (MAAARC), Acharya Nagarjuna University, Nagarjuna Nagar-522 510, Guntur Dt. A. P., India.
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S. Rabia Banu
  • S. Rabia Banu
  • Department of Zoology, Osmania College (UG & PG), Kurnool-518 004, A.P., India.
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P. Indira
  • P. Indira
  • Department of Zoology, S.K. University, Ananthapur-515 001, A.P., India.
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  •  Received: 28 February 2015
  •  Accepted: 13 April 2015
  •  Published: 30 April 2015

Abstract

This study was carried out to investigate the sub-lethal effect of cypermethrin on acetylcholinesterase (AChE) activity and acetylcholine (ACh) content in various organ tissues of Channa striatus. Activity of AChE and ACh content was estimated in the tissues of brain, gills, liver, kidney, intestine and muscle of the exposed fish at regular intervals of 1, 7, 15 and 30 days. The study revealed that the inhibition of the enzyme activity followed by a concomitant increase of ACh content was observed in all the tissues of C. striatus during the exposed period. It was also observed that there was a sudden increase in the AChE activity during 24 h exposure. Enhancement in the activity of AChE might be due to the stress experienced by the fish during the experimental period.

 

Key words:  Cypermethrin, acetylchonesterase (AChE), acetylcholine (Ach), Channa striatus.