April 2012

In vitro antioxidant activities and inhibitory effects of aqueous extracts of unripe plantain pulp (Musa paradisiaca) on enzymes linked with type 2 diabetes and hypertension

The dried plantain pulps were crushed and milled into flour (Raw flour), while a portion of its flour was reconstituted in boiling water to form a thick paste known locally in Western Nigeria as ‘amala’. This was dried and milled into ‘Amala’ flour. The aqueous extracts of raw and ‘amala’ flour were prepared (1 g/20 mL). The phenolic contents, vitamin C and antioxidant properties...

Author(s): Sidiqat A.Shodehinde and Ganiyu Oboh

April 2012

Paraphenylenediamine induces apoptosis of Murine myeloma cells in a reactive oxygen species dependant mechanism

Paraphenylenediamine (p-PD) is the main aromatic amine used in the formulation of hair dyes. Epidemiologic studies have suggested that the use of p-PD based hair dyes might be related to increase risk of human malignant tumors including multiple myeloma and hematopoietic cancers. However, the toxicity of p-PD on myeloma cells has not been well elucidated yet. Therefore, the association between the cytotoxicity of p-PD...

Author(s): Zineb Elyoussoufi, Norddine Habti, Said  Motaouakkil, and Rachida Cadi