December 2009

Organic pollution from the Songhua River induces NIH 3T3 cell transformation: Potential risks for human health

Epidemiological investigation has shown that organic contamination of the Songhua River is a risk factor for tumor development among residents who live nearby. A mutagenesis is induced by organic contamination using short-term genotoxic bio-assays. To further investigate the risk of carcinogenic potential to human health, the NIH3T3 cell line was used to examine the induction of transformation by diethyl...

Author(s): Jia-Ren Liu, , Hong-Wei Dong, Xuan-Le Tang, Jia Yu, Xiao-Hui Han, Bing-Qing Chen, Chang-Hao Sun and Bao-Feng Yang

December 2009

Comparative nephrotoxic effect associated with exposure to diesel and gasoline vapours in rats

Comparative effect of exposure to 20.7 ± 5.8 cm3 h-1kg-1m-3 day-1 of diesel and gasoline vapours on the kidney functions was assessed in rats. It was observed that exposure to diesel and gasoline vapours produced a significant increase (P < 0.05) in serum creatinine, urea, BUN, uric acid, glucose and K+; and a significant decrease (P < 0.05) in serum Na+ and Cl- levels. However, the percentage...

Author(s): F. E. Uboh, M. I. Akpanabiatu, J. I. Ndem, Y. Alozie and P. E. Ebong