Scientific Research and Essays

  • Abbreviation: Sci. Res. Essays
  • Language: English
  • ISSN: 1992-2248
  • DOI: 10.5897/SRE
  • Start Year: 2006
  • Published Articles: 2740

Full Length Research Paper

New HPLC method for the determination of artemether in injections

B Nasir1, SNH Shah1, G Murtaza2*, N Shahid1, M Akhtar3, BA Khan3, S Azhar2, A Mumtaz4, A Waseem4, SA Khan2, M Ubaid2, S Noreen5, B kamal2, MHHB Asad2
  1Faculty of Pharmacy, Bahauddin Zakariya University, Multan, Pakistan. 2Department of Pharmaceutical Sciences, COMSATS Institute of Information Technology, Abbottabad, Pakistan. 3Department of Pharmacy, the Islamia University of Bahawalpur, Bahawalpur, Pakistan. 4Department of Chemistry, COMSATS Institute of Information Technology, Abbottabad, Pakistan. 5Department of Chemistry, University of Sargodha, Sargodha, Pakistan.
Email: [email protected]

  •  Accepted: 16 February 2012
  •  Published: 16 March 2012

Abstract

 

This new economical HPLC method has been developed for the estimation of artemether in injections to reduce the cost of estimation. Previously, one HPLC method is available in European Pharmacopoeia for the estimation of artemether but it is costly due to high price of acetonitrile. Present study replaced acetonitrile with methanol and showed that new method remained as specific, linear, accurate and precise as previous.

 

Key words: Artemether, injections, HPLC, acetonitrile, methanol.