Scientific Research and Essays

  • Abbreviation: Sci. Res. Essays
  • Language: English
  • ISSN: 1992-2248
  • DOI: 10.5897/SRE
  • Start Year: 2006
  • Published Articles: 2754

Full Length Research Paper

Urinary tract infection in Okada village: Prevalence and antimicrobial susceptibility pattern

Nwanze, P. I.1, Nwaru, L. M.2*, Oranusi, S.1, Dimkpa, U.5, Okwu, M. U.1, Babatunde, B. B.1, Anake, T. A.3, Jatto, W.1 and Asagwara, C. E.4
1Department of Biological Sciences, College of Natural and Applied Sciences, Igbinedion University, Okada, P.M.B. 0006, Edo State, Nigeria. 2Department of Medical Laboratory Science, College of Health Science, Igbinedion University, Okada, Edo State, Nigeria. 3Department of Mathematics, College of Science and Technology, Covenant University, Canaanland, Ota Ogun State, Nigeria 4General Outpatient Department, Igbinedion University Teaching Hospital, Okada Edo State, Nigeria 5Department of Physiology, School of Basic Medical Sciences, Igbinedion University, Okada, Edo State, Nigeria.
Email: [email protected]

  •  Accepted: 11 April 2007
  •  Published: 30 April 2007

Abstract

The antimicrobial sensitivity pattern of bacterial isolates from suspected urinary tract infection (UTI) patients at Igbinedion University Teaching Hospital was carried out from November 2004 to November 2005 using the disc diffusion method. The subjects were made up of 330 (60%) males and 220 (40%) females. The commonest isolates were Escherichia coli (51.2%), Staphylococcus aureus (27.3%), and Klebsiella pneumoniae (12.8%) respectively. Both methicillin-resistant (MRSA) and methicillin sensitive (MSSA) S. aureus were isolated in the study. The isolates were highly sensitive to ofloxacin but low to moderately sensitive to gentimicin, tobramycin, nalidixic acid, ciprofloxacin, tetracycline, nitrofurantoin, and cefuroxine. The MSSA isolates were highly sensitive to ciprofloxaxin and ofloxacin while the MRSA were sensitive to ofloxacin. In addition, the isolates showed multi-drug resistance.

 

Key words: Bacterial resistance, b-lactamases, methicillin-resistant Staphylococcus aureus (MRSA), methicillin sensitive (MSSA) S. aureus.