African Journal of
Biotechnology

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12486

Full Length Research Paper

Mosquito larvicidal trihydroxylindene derivative from submerged cultures of Trametes species

Abigail Wambui Waweru
  • Abigail Wambui Waweru
  • Department of Chemistry, Egerton University, P. O. Box 536 20115-Egerton, Kenya.
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Josiah Ouma Omolo
  • Josiah Ouma Omolo
  • Department of Chemistry, Egerton University, P. O. Box 536 20115-Egerton, Kenya.
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Peter Kiplagat Cheplogoi
  • Peter Kiplagat Cheplogoi
  • Department of Chemistry, Egerton University, P. O. Box 536 20115-Egerton, Kenya.
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Alice Wanjiku Njue
  • Alice Wanjiku Njue
  • Department of Chemistry, Egerton University, P. O. Box 536 20115-Egerton, Kenya.
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  •  Received: 06 November 2015
  •  Accepted: 02 March 2016
  •  Published: 28 June 2017

Abstract

Larvicidal active pure chemical compound was isolated from a Trametes species using conventional chemistry techniques like solvent-solvent extraction and liquid-solid adsorption techniques. Larvicidal assays carried out on the purified compound, LC50 and LC90 values were calculated and found to be 23.5 and 67.4 ppm, respectively. The chemical structures of the purified compound was elucidated using standard spectroscopic techniques: 1D (1H; 13C) and 2D (HSQC, COSY, NOESY, HMBC; DEPT) NMR experiments, assignments. The results indicate the potential of novel compounds with mosquito larvicidal activity from the Trametes species commonly found in the Kenyan forest ecosystems.

Key words: Mosquito larvicidal, Aedes aegypti, trihydroxylindene derivative, Trametes species.

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

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