African Journal of

  • Abbreviation: Afr. J. Biotechnol.
  • Language: English
  • ISSN: 1684-5315
  • DOI: 10.5897/AJB
  • Start Year: 2002
  • Published Articles: 12485

Table of Content: 28 June, 2017; 16(26)

June 2017

Role of leucine rich repeat and Ig domain containing 1 (LINGO1) in demyelinating and neurological diseases and investigation of conserved residues by docking analysis for novel therapeutic options

A demyelinating sickness is any ailment of the nervous system in which the myelin casing of neurons is injured. This harm weakens the transmission of signals in the pretentious nerves. Demyelinating diseases, like multiple sclerosis (MS) and Charcot-Marie-Tooth (CMT) disease, are categorized on the basis of the scratch of the myelin covering around neurons, because of swelling and gliosis in the central nervous system...

Author(s): Sumair Kanwal and Shazia Perveen

June 2017

A new immunoregulatory agent from Rosa damascena reduces CD3 expression in human peripheral blood mononuclear cells (PBMCs)

T-Lymphocytes (T-cells) play a dominant role in the initiation and maintenance of autoimmune inflammatory processes. They become activated by the presentation of antigen such as auto antigen. A main feature of T-cell activation is the production of cytokines. Though, uncontrolled T-cells activation through T-cell receptor (TCR) has been linked to numerous autoinflammatory and autoimmune pathologies. This study...

Author(s): Albogami Sarah

June 2017

Evaluation of hygienic quality of ferment of local beer “dolo” used as condiment in Burkina Faso

Rabilé is a ferment of local beer called “dolo” in Burkina Faso. It is used for local beer production and as condiment in sauces. Its process of production could be a source of contamination. So the quality of ferment needs to be guaranteed for consumers’ health. The aim of the study was to control the hygienic quality of local ferment consumed in Burkina Faso. A total of 70 samples were...

Author(s): MOGMENGA Iliassou, SOMDA Kounbèsiounè Marius, KEITA Ibrahim and TRAORE Sababénédyo Alfred

June 2017

Mosquito larvicidal trihydroxylindene derivative from submerged cultures of Trametes species

Larvicidal active pure chemical compound was isolated from a Trametes species using conventional chemistry techniques like solvent-solvent extraction and liquid-solid adsorption techniques. Larvicidal assays carried out on the purified compound, LC50 and LC90 values were calculated and found to be 23.5 and 67.4 ppm, respectively. The chemical structures of the purified compound was elucidated using standard...

Author(s): Abigail Wambui Waweru, Josiah Ouma Omolo, Peter Kiplagat Cheplogoi and Alice Wanjiku Njue

June 2017

Comparison of in vitro antioxidant activity of some selected seaweeds from Algerian West Coast

In vitro antioxidant activity of methanolic (ME) and ethanolic (ET) extracts of six species of seaweeds (Cystoseira stricta, Cystoseira compressa, Corallina elongata, Porphyra umbilicalis, Enteromorpha compressa and Ulva lactuca) collected from Algerian West Coast was evaluated, using 1,1-diphenyl-2-picryl-hydrazyl (DPPH) radical scavenging assay and reducing power assay. They were tested for total phenolic content. The...

Author(s): Hanane Oucif, Rebiha Adjout, Rahma Sebahi, Farida Ouda Boukortt, Smail Ali-Mehidi and Sidi-Mohamed El-Amine Abi-Ayad

June 2017

Traditional dishes consumed in Zimbabwe and high-performance liquid chromatography (HPLC) quantitation of their antioxidant phytochemicals

Diabetes type 2, cancers, hypertension and obesity have become problematic diseases worldwide calling for more studies on their prevention and management. Antioxidant phytochemicals have shown potential to reduce cases of such chronic diseases therefore the present study quantified antioxidant phytochemicals in traditional dishes consumed in Zimbabwe. Traditional dishes are readily available therefore are cheap and...

Author(s): Dzomba, P., Gwatidzo, L., Mugari, P. and Mupa, M.

June 2017

Interactive effect of colloidal solution of zinc oxide nanoparticles biosynthesized using Ocimum gratissimum and Vernonia amygdalina leaf extracts on the growth of Amaranthus cruentus seeds

Nanofertilizers may be a possible replacement for organic fertilizers because they can get to targeted sites in a plant and either enhance or thwart its growth depending on the toxicity level of the used nanoparticles. Zinc oxide nanoparticles are said to be a good source of nutrients for crop production and using these nanoparticles as bio fertilizers, could help to reduce the chemical residue in the grown vegetables...

Author(s): Rebecca Emmanuel Mfon, Ngozi Ifeoma Odiaka and Andrei Sarua