This study investigates how work-life balance practices impact employee outcomes such as job satisfaction, productivity, and well-being in multicultural work environments in Ghana. A cross-sectional study was conducted using an online survey of 336 participants from diverse cultural backgrounds across four regions in Ghana. The findings indicate that factors including leadership support, flexible policies, fair compensation, training opportunities, and organizational culture significantly influence work-life balance and employee performance and retention. Age, gender, income level, and marital status also moderate this relationship. The results highlight the need for inclusive policies tailored to the unique needs of different demographic groups to enhance work-life balance. Fostering diversity, equity, and flexibility is ethically upright and strategically imperative for organizational success through improved employee outcomes. This study contributes empirical insights on managing work-life balance effectively across cultural contexts, helping multinational organizations support a global workforce.

Keywords: Work-life balance; employee outcome; turnover; satisfaction; compensation; management;