African Journal of
Food Science

  • Abbreviation: Afr. J. Food Sci.
  • Language: English
  • ISSN: 1996-0794
  • DOI: 10.5897/AJFS
  • Start Year: 2007
  • Published Articles: 869

Full Length Research Paper

Two withanolides from Withania somnifera (solanaceae) and activity of methanolic extracts against fungal and bacterial pathogens that affects food crops

Regina Chepkorir
  • Regina Chepkorir
  • Department of Chemistry, Egerton University, Kenya.
  • Google Scholar
Josphat Clement Matasyoh
  • Josphat Clement Matasyoh
  • Department of Chemistry, Egerton University, Kenya.
  • Google Scholar
Isabel N. Wagara
  • Isabel N. Wagara
  • Department of Biological Sciences, Egerton University, Kenya.
  • Google Scholar

  •  Received: 16 August 2016
  •  Accepted: 15 September 2016
  •  Published: 31 May 2018


Bashir HS, Mohammed AM, Magsoud AS, Shaoub AM (2013). Isolation of Three Flavanoids from Withania somnifera leaves (solanaceae) and Their Antimicrobial Activities. J. Forest Prod. Ind. 2(5):39-45.


Baskaran C, Velu S (2012). Phytochemical analysis and In-Vitro antimicrobial activity of Withania Somnifera (Ashwagandha). J. Nat. Prod. 2(6):711-716.


Khan M Rahman, M.S Islam. (2008). Antimicrobial susceptibility of Brazilian Clostridium difficile strains determined by agar dilution and disk diffusion. DARU. J. . Pharm. Sci. 16: 239-244.


Lal P, Misra L, Sangwan RS, Tuli R (2006). New Withanolides from the Berries of Withania somnifera. Z. Naturforsch B 61(9):1143-1147.


Mirjalili MH, Moyano E, Bonfill M, Cusido RM, Palazón J (2009). Steroidal Lactones from Withania Somnifera, an ancient plant for Novel Medicine. Molecules 14:2373-2393.


Misra L, Mishra P, Pandey A, Sangwan RS, Sangwan NS, Tuli R (2007). Withanolides from Withania somnifera roots. Phytochemistry 69(4):1000-1004.


Oza VP, Parma PP, Kumar S, Subramanian RB (2010). Anticancer properties of highly purified L-asperaginase from withania Somnifera against acute lymphoblastic leukemia. Evid. Based Complement. Alternat. Med. 160(96):1833-1840.


Rani A, Baranwal NR, Nema RK (2012). Pharmacognostical and Phytochemical studies of Withania Somnifera, Linn. Asian J. Biochem. Pham. Res. 2(4):195-198.


Singariya P, Kumar P, Mourya KK (2012). Evolution of antimicrobial activity of leaf Extracts of Winter Cheery (Withania Somnifera). Int. J. Pharm. Tech. Res. 4(3):1247-1253.


Singh G, Sharma PK, Dudhe R, Singh S (2010). Biological activities of Withania somnifera. Ann. Biol. Res. 1(3):56-63.


Strange RN, Scott PR (2005). Plant Disease: A global food Security. Annu. Rev. Phytopathol. 43:83-116.


Sule IO, Agbabiaka TO (2008). Antibacterial Effect of some Plant Extracts on Selected Enterobacteriaceae. Ethnobot. Leafl. 12:1035-1042.


Wahi AK, Singh A, Singh AK (2011). Determination of Minimum Inhibitory Concentration (MIC) of some Novel Triazole Derivative. Int. J. Res. Pharm. Chem. 1(4):2231-2781.


Yeo SF, Livermore DM (1994). Effect of inoculum size on the in-Vitro Susceptibility to beta-lactam antibiotics of M.Catarrhalis isolates of different beta-lactamase types. J. Med. Microbiol. 40(4):252-255.