African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5233

Full Length Research Paper

Isolation of lectin and lectin derivatives from Haworthia limifolia: An in-vitro investigation

R. M. Coopoosamy* and K. K. Naidoo
Department of Nature Conservation, Faculty of Natural Science, Mangosuthu University of Technology, P. O. Box 12363, Jacobs, 4026, Durban, South Africa
Email: [email protected]

  •  Accepted: 27 February 2012
  •  Published: 23 April 2012

Abstract

The ability for medicinal plants to aid in wound healing lends itself to cell-agglutinating and sugar-specific protein. These are collectively termed lectins. Although, the function of these lectins in plants are limiting, the benefit to human in terms of wound healing is of vital importance. With many new infections arising as a result of bacteria, fungi and viruses developing immunity against western medicines, the world is now turning towards natural medicines as an alternative source for cures. Harworthia limifolia is currently used by indigenous people for sun burns, burns, sores as well as a systemic remedy and spiritual benefits. The population in the wild has drastically being reduced due to the pressures of harvesting by traditional healers for trade purposes. The current study investigates the presence of lectins or lectin like derivatives in H. limifolia. The derivatives were tested against rat, rabbit and human serum, and a positive reaction with human α-2-macroglobulin was observed. Furthermore anti-tumor and wound healing properties have been validated.

 

Key words: Haworthia limifolia, lectins, agglutination, traditional use