African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5233

Full Length Research Paper

Mitochondrion activity and dispersal of Aspergillus fumigatus and Rhizopus oryzae

Desmond M. Ncango1, Chantel W. Swart1, Carolina H. Pohl1, Pieter W. J. Van Wyk2 and Johan L. F. Kock1*  
  1UNESCO MIRCEN, Department of Microbial, Biochemical and Food Biotechnology, University of the Free State, P.O. Box 339, Bloemfontein, 9301, South Africa. 2Centre for Microscopy, University of the Free State, P.O. Box 339, Bloemfontein, 9301, South Africa.
Email: [email protected]

  •  Accepted: 23 March 2010
  •  Published: 04 May 2010

Abstract

 

We investigated the effects of anti-inflammatory and anti-mitochondrial compounds on spore dispersal in the pathogens, Aspergillus fumigatus andRhizopus oryzae. When acetylsalicylic acid (ASA) and other non steroidal anti-inflammatory drugs (NSAIDs) were added to bio-assays of A. fumigatus and R. oryzae, spore-releasing structures were targeted first at lower concentrations. Similar results were obtained when oxygen was limited. These spore-releasing structures contained increased levels of mitochondrion activity compared to hyphae. We concluded that increased mitochondrion activity is necessary for dispersal of A. fumigatus and R. oryzae.

 

Key words: Aspergillus fumigatus, bio-assay, mitochondrion activity, non steroidal anti-inflammatory drugs, Rhizopus oryzae, spore-releasing structure.

 

Copyright © 2024 Author(s) retain the copyright of this article.

This article is published under the terms of the Creative Commons Attribution License 4.0

Back to Vol. 4 No. 9
Back to articles
  • Articles on Google by:
SUBSCRIBE TO RSS
SUBMIT MANUSCRIPT
CONFERENCES