African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5233

Full Length Research Paper

Effect of N-acyl homoserine lactones (AHLs) quorum sensing signal molecules on Enterococcus faecalis biofilm formation

Karima Bensalem*
  • Karima Bensalem*
  • Department of Biochemistry, Faculty of Sciences, University of Badji Mokhtar Annaba (UBMA), BP12 Sidi Amar, 23000 Annaba, Algeria
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Ryad Djeribi
  • Ryad Djeribi
  • Department of Biochemistry, Faculty of Sciences, University of Badji Mokhtar Annaba (UBMA), BP12 Sidi Amar, 23000 Annaba, Algeria
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Francisco Javier López Baena
  • Francisco Javier López Baena
  • Department of Microbiology, Faculty of Biology, University of Seville (US), Avenue Reina Mercedes, 6-41012 Seville, Spain
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  •  Received: 03 June 2014
  •  Accepted: 04 August 2014
  •  Published: 20 August 2014

Abstract

The Gram-positive bacterium Enterococcus faecalis is an etiological agent of endodontic infections in oral biofilms. In the present study, we analyzed the effect of N-acyl homoserine lactones (AHLs) quorum sensing signal molecules on E. faecalis biofilm formation ability. Our results provide important effects of N-Hexanoyl-L-homoserine lactone (C6-HSL) and N-octanoyl-L-homoserine lactone (C8-HSL) molecules on E. faecalis biofilm formation. These AHLs molecules promoted the biofilm formation of E. faecalis.

 

Key words: N-acyl homoserine lactones (AHLs), bacterial communication, biofilm, Enterococcus faecalis, quorum sensing.

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This article is published under the terms of the Creative Commons Attribution License 4.0

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