Abstract

Thirty three (33) strains of Klebsiella aerogenes isolated from 197 in-and out-patients with symptoms of urinary tract infection (UTI) at University of Benin Teaching Hospital (UBTH), Benin City were used for this study. Twenty-one antibiotics were used for the antibiogram typing. Organisms were isolated from 65 positive samples, with the most prevalent beingStaphylococcus aureus (40.0%), others were Escherichia coli (26.2%), Pseudomonas aeruginosa (12.3%), Klebsiella spp (9.2%), Proteus spp (6.2%), Acinetobacter spp (4.6%) and Providencia spp (1.5%). Majority of the isolates were highly sensitive to the quinolones (47.3%) and less sensitive to the penicillins (7.2%). Isolates of Pseudomonas aeruginosawere most sensitive to ofloxacin (50.0%), rifampicin (50.0%) and even gentamycin (50.0%), and less sensitive to tetracycline and chloramphenicol (12.5%) respectively. This study is of great concern to public health; it is suggested that suitable antimicrobial intervention should be administered to reduce the risk of multidrug-resistant (MDR) pathogens.

Key words: Antibiotics, multidrug-resistant, uropathogens, public health.