African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 5182

Full Length Research Paper

Antimicrobial activity and FTIR characterization of lapachol derivatives against Staphylococcus aureus

Antonio Wilton Cavalcante Fernandes
  • Antonio Wilton Cavalcante Fernandes
  • Programa de Recursos Naturais do Semiárido – PgRNS of Federal University of São Francisco Valley, Brazil.
  • Google Scholar
Victoria Laysna dos Anjos Santos
  • Victoria Laysna dos Anjos Santos
  • Pharmacy da Federal University of São Francisco Valley, Brazil.
  • Google Scholar
Cleonia Roberta Melo Araujo
  • Cleonia Roberta Melo Araujo
  • Collegiate Pharmaceutical Sciences da Federal University of São Francisco Valley, Brazil.
  • Google Scholar
Edigenia Cavalcante da Cruz Araujo
  • Edigenia Cavalcante da Cruz Araujo
  • Collegiate Pharmaceutical Sciences da Federal University of São Francisco Valley, Brazil.
  • Google Scholar
Helinando Pequeno de Oliveira
  • Helinando Pequeno de Oliveira
  • Federal University of São Francisco Valley, Brazil.
  • Google Scholar
Mateus Matiuzzi da Costa
  • Mateus Matiuzzi da Costa
  • Federal University of São Francisco Valley, Brazil.
  • Google Scholar


  •  Accepted: 06 February 2017
  •  Published: 14 June 2017

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Araújo CRM, Santos VLA, Guimarães DG, Oliveira-Junior RG, Almeida JRGS, Gonsalves AA (2014). Síntese e Determinação in vitro do FPS-UVB de oximas Derivadas do Lapachol. Rev. Virtual Quím. 6:1702-1712.

 
 

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Barbosa TP, Neto HD (2013). Preparação de derivados do Lapachol em meio ácido e em meio básico: uma proposta de experimentos para a disciplina de Química Orgânica Experimental. Quim. Nova. 36:331-334.
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Ferreira SB, Gonzaga DTG, Santos WC, Araújo KGL, Ferreira VF (2010). β-Lapachona: Sua Importância em Química Medicinal e Modificações Estruturais. Rev. Virtual Quim. 2:140-160.

 
 

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Fonseca SGC (2003). Lapachol – química, farmacologia e métodos de dosagem. Rev. Bras. Farm. 84:9-16.

 
 

Kumagai Y (2012). The chemical biology of naphtho-quinones and its environmental implications. Annu. Rev. Pharmacol. Toxicol. 52:221-247.
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Kumagai Y, Shinkai Y, Miura T, Cho AK (2012). The Chemical Biology of Naphthoquinones and Its Environmental Implications. Annu. Rev. Pharmacol. Toxicol. 52:221-247.
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Macedo L, Fernandes T, Silveira L, Mesquita A, Franchitti AA, Ximenes EA (2013). Lapachone activity in synergy with conventional antimicrobials against methicillin resistant Staphylococcus aureus strains. Phytomed. 21:25-29.
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Oliveira AKM (2006). Caracterização Morfológica, Viabilidade e Vigor das sementes de Tabebuia áurea I (Silva Manso) Benth. & Hook. F. ex. S. Moore. Rev. Árvore 30:25-32.
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Paharik AE, Horswill AR (2016). Staphylococcal Biofilm: Adhesins, Regulation, and Host Response. Microbiol. Spectr. 4(2):529-566.

 
 

Pavia DL, Lampman GM, Kriz GS (2001). Introduction to Spectroscopy. 3rd Edition, Thomson Learning.

 
 

Park JH Lee J H, Kim CJ, Lee JC, Cho MH, Lee J (2012). Extracellular protease in Actinomycetes culture supernatants inhibits and detaches Staphylococcus aureus biofilm formation. Biotechnol. Lett. 34:655-661.
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Taylor PW (2013). Alternative natural sources for a new generation of antibacterial. Int. J. Antibacterial Agents 42:195-201.
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Trentin DS, Giordani RB., Zimmer KR, Silva AG da, Silva MV da, Correia MT, Baumvol IJ, Macedo AJ (2011). Potential of medicinal plants from the Brazilian semi-arid region (Caatinga) against Staphylococcus epidermidis planktonic and biofilm lifestyles. J. Ethnopharmacol.137:327-335.
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Wu S, Duan N, Gu H, Hao L, Ye H, Gong W, Wang Z (2016). A Review of the Methods for Detection of Staphylococcus aureus Enterotoxins. Toxins 8:176.
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