African Journal of
Microbiology Research

  • Abbreviation: Afr. J. Microbiol. Res.
  • Language: English
  • ISSN: 1996-0808
  • DOI: 10.5897/AJMR
  • Start Year: 2007
  • Published Articles: 4989

Full Length Research Paper

Effectiveness of commonly used antiseptics on bacteria causing nosocomial infections in tertiary hospital in Malaysia

Hassanain Al-Talib
  • Hassanain Al-Talib
  • Department of Medical Microbiology and Parasitology, Faculty of Medicine, Universiti Teknologi MARA (UiTM) – Sungai Buloh, Malaysia.
  • Google Scholar
Alyaa Alkhateeb
  • Alyaa Alkhateeb
  • Biochemistry and Molecular Medicine Department, Faculty of Medicine, Universiti Teknologi MARA (UiTM) – Sungai Buloh, Malaysia.
  • Google Scholar
Ahmad Syahrizal Ahmad Ruzuki
  • Ahmad Syahrizal Ahmad Ruzuki
  • Institute for Medical Molecular Biotechnology, Faculty of Medicine, Universiti Teknologi MARA (UiTM) – Sungai Buloh, Malaysia.
  • Google Scholar
Nadia Farhana Zulkifli
  • Nadia Farhana Zulkifli
  • Institute for Medical Molecular Biotechnology, Faculty of Medicine, Universiti Teknologi MARA (UiTM) – Sungai Buloh, Malaysia.
  • Google Scholar
Syakirah Hamizi
  • Syakirah Hamizi
  • Institute for Medical Molecular Biotechnology, Faculty of Medicine, Universiti Teknologi MARA (UiTM) – Sungai Buloh, Malaysia.
  • Google Scholar
Nur Syazwani Muhammad
  • Nur Syazwani Muhammad
  • Institute for Medical Molecular Biotechnology, Faculty of Medicine, Universiti Teknologi MARA (UiTM) – Sungai Buloh, Malaysia.
  • Google Scholar
Amilah Fadhlina Abd Karim
  • Amilah Fadhlina Abd Karim
  • Institute for Medical Molecular Biotechnology, Faculty of Medicine, Universiti Teknologi MARA (UiTM) – Sungai Buloh, Malaysia.
  • Google Scholar


  •  Received: 23 January 2019
  •  Accepted: 04 March 2019
  •  Published: 14 March 2019

References

Al-Talib HI, Yean CY, Al-Jashamy K, Hasan H (2010). Methicillin-resistant Staphylococcus aureus nosocomial infection trends in Hospital Universiti Sains Malaysia during 2002-2007. Annals of Saudi medicine 30(5):358-363.
Crossref

 

Bigliardi PL, Alsagoff SAL, El-Kafrawi HY, Pyon JK, Wa CTC, Villa MA (2017). Povidone iodine in wound healing: A review of current concepts and practices. International Journal of Surgery 44:260-268.
Crossref

 
 

Bouaziz A, Dib AL, Aimeur R, Lakhdara N, Bererhi N, Boureni A, Bouaziz O, Miguel GE, Elena RM, Elena RE (2016). Evaluation of the bactericidal efficacy of different dilutions of tincture of iodine on three bacterial reference strains. Journal of Chemical and Pharmaceutical Research 8(3):242-245.

 
 

Brudzynski K (2006). Effect of hydrogen peroxide on antibacterial activities of Canadian honeys. Canadian Journal of Microbiology 52(12):1228-1237.
Crossref

 
 

Cariz J (2018). Hospital Superbug Becoming Resistant to Alcohol Disinfectants. 

View. Accessed 27/2/2019.

 
 

Cheung HY, Wong MM, Cheung SH, Liang LY, Lam YW, Chiu SK (2012). Differential actions of chlorhexidine on the cell wall of Bacillus subtilis and Escherichia coli. PloS One 7(5):1-12.
Crossref

 
 

Climo MW, Yokoe DS, Warren DK, Perl TM, Bolon M, Herwaldt LA, Weinstein RA,Sepkowitz KA, Jernigan JA, Sanogo K, Wong EW (2013). Effect of daily chlorhexidine bathing on hospital-acquired infection. The New England Journal of Medicine 368(6):533-542.
Crossref

 
 

Ekizoglu M, Sagiroglu M, Kilic E, Hascelik AG (2016). An investigation of the bactericidal activity of chlorhexidine digluconateagainst multidrug-resistant hospital isolates. Turkish Journal of Medical Sciences 46(3):903-909.
Crossref

 
 

El-Mahmood AM, Doughari JH (2009). Bacteriological examination of some diluted disinfectants routinely used in the Specialist Hospital Yola, Nigeria. African Journal of Pharmacy and Pharmacology 3(5):185-190.

 
 

Estrela C, Ribeiro RG, Estrela CR, Pecora JD, Sousa-Neto MD (2003). Antimicrobial effect of 2% sodium hypochlorite and 2% chlorhexidine tested by different methods. Brazilian Dental Journal 14(1):58-62.
Crossref

 
 

European Society of Clinical Microbiology and Infectious Diseases (2003). Determination of minimum inhibitory concentrations (MICs) ofantibacterial agents by broth dilution. Clinical Microbiology and Infection 9(8):1-7.

 
 

Frost, Sullivan (2011). Hospital-acquired Infection Incidence - Trends in Malaysia.

View acceseed 27/2/2019.

 
 

Hegde A, Bhat GK, Mallya S (2008). Effect of exposure to hydrogen peroxide on the virulence of Escherichia coli. Indian Journal of Medical Microbiology 26(1):25-28.
Crossref

 
 

Kampf G, Kramer A (2004). Epidemiologic background of hand hygiene and evaluation of the most important agents for scrubs and rubs. Clinical Microbiology Reviews 17(4):863-893.
Crossref

 
 

Kenar L, Ortatatli M, Yaren H, Karayilanoglu T, Aydogan H (2007). Comparative sporicidal effects of disinfectants after release of a biological agent. Military Medicine 172(6):616-621.
Crossref

 
 

Kouchak F, Askarian M (2012). Nosocomial infections: the definition criteria. Iranian Journal of Medical Sciences 37(2):72-73.

 
 

Lanjri S, Uwingabiye J, Frikh M, Abdellatifi L, Kasouati J, Maleb A, Bait A, Lemnouer A, Elouennass M (2017). In vitro evaluation of the susceptibility of Acinetobacter baumannii isolates to antiseptics and disinfectants: comparison between clinical and environmental isolates. Antimicrobial Resistance and Infection Control 6(36):1-7.
Crossref

 
 

Lemmen S, Scheithauer S, Hafner H, Yezli S, Mohr M, Otter JA (2015). Evaluation of hydrogen peroxide vapor for the inactivation of nosocomial pathogens on porous and nonporous surfaces. American Journal of Infection Control 43(1):82-85.
Crossref

 
 

Mahon CR, Lehman DC, George M (2014). Textbook of Diagnostic Microbiology 5ed: Elsevier.

View

 
 

Mai-Prochnow A, Lucas-Elio P, Egan S, Thomas T, Webb JS, Sanchez-Amat A, Kjelleberget S (2008). Hydrogen peroxide linked to lysine oxidase activity facilitates biofilm differentiation and dispersal in several gram-negative bacteria. Journal of Bacteriology 190(15):5493-5501.
Crossref

 
 

Mangram AJ, Horan TC, Pearson ML, Silver LC, Jarvis WR (1999). Guideline for Prevention of Surgical Site Infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee. American Journal of Infection Control 27(2):97-132.
Crossref

 
 

Matthew EW, Lucy JB, Laura CB, Sutton JM (2017). Mechanisms of increased resistance to chlorhexidine and cross-resistance to colistin following exposure of Klebsiella pneumoniae clinical isolates to chlorhexidine. Antimicrobial Agents and Chemotherapy 61(1):1-12.

 
 

Mbajiuka C, Onuoha S, Ugah U (2015). Comparative studies of the efficacy of some disinfectants on human pathogens. Researcher 7(1):39-45.

 
 

McDonnell G, Russell AD (1999). Antiseptics and disinfectants: activity, action, and resistance. Clinical Microbiology Reviews 12(1):147-179.
Crossref

 
 

McKeen LW (2012). Introduction to Food Irradiation and Medical Sterilization. The effects of sterilization on Plastics and Elastomers. Oxford - United Kindom Elsevier; P 27.
Crossref

 
 

Mullany LC, Darmstadt GL, Tielsch JM (2006). Safety and impact of chlorhexidine antisepsis interventions for improving neonatal health in developing countries. The Pediatric Infectious Disease Journal 25(8):665-675.
Crossref

 
 

Murthy MB, Krishnamurthy B (2009). Severe irritant contact dermatitis induced by povidone iodine solution. Indian Journal of Pharmacology 41(4):199-200.
Crossref

 
 

Nishimura C (2006). Comparison of the antimicrobial efficacy of povidone-iodine, povidone- iodine-ethanol and chlorhexidine gluconate-ethanol surgical scrubs. Dermatol 212 Suppl 1(21-25).
Crossref

 
 

Pidot SJ, Gao W, Buultjens AH, Monk IR, Guerillot R, Carter GP, Lee JYH, Lam MMC, Grayson ML, Ballard SA, Mahony AA, Grabsch EA, Kotsanas D, Korman TM, Coombs GW, Robinson JO, da Silva AG, Seemann T, Howden BP, Johnson PDR, Stinear TP (2018). Increasing tolerance of hospital Enterococcus faecium to handwash alcohols. Science Translational Medicine 10(452):eaar6115.

 
 

Raines K, Rosen K (2016). The effect of chlorhexidine bathing on rates of nosocomial infections among the critically ill population: An analysis of current clinical research and recommendations for practice. Dimensions of Critical Care Nursing35(2):84-91.
Crossref

 
 

Russell AD (1999). Bacterial resistance to disinfectants: present knowledge and future problems. The Journal of Hospital Infection 43(Supplement):S57-S68.
Crossref

 
 

Russell AD, Tattawasart U, Maillard JY, Furr JR (1998). Possible link between bacterial resistance and use of antibiotics and biocides. Antimicrobial Agents and Chemotherapy 42(8):2151.
Crossref

 
 

Rutala WA, Barbee SL, Aguiar NC, Sobsey MD, Weber DJ (2000). Antimicrobial activity of home disinfectants and natural products against potential human pathogens. Infection Control and Hospital Epidemiology 21(1):33-38.
Crossref

 
 

Shahriari S, Mohammadi Z, Mokhtari MM, Yousefi R (2011). Effect of hydrogen peroxide on the antibacterial substantivity of chlorhexidine. International Journal of Dentistry 2010:1-4.
Crossref

 
 

Sridhar PN (2012). Testing of disinfectants.

View

 
 

Tuhina B, Joel F, Shampa A (2013). Comparative analysis of newly introduced disinfectants in hospitals in India: An important aspect of infection control policy. International Journal of Infection Control 9(1):1-5.

 
 

Vernon MO, Hayden MK, Trick WE, Hayes RA, Blom DW, Weinstein RA (2006). Chlorhexidine gluconate to cleanse patients in a medical intensive care unit: the effectiveness of source control to reduce the bioburden of vancomycin-resistant enterococci. Archives of Internal Medicine 166(3):306-312.
Crossref

 
 

Wayne P (2012). Clinical Laboratory Standards Institute. In: Performance standards for antimicrobial susceptibility testing. M100-S22.

 
 

William AR, David JW, the Healthcare Infection Control Practices Advisory Committee (HICPAC) (2008). Guideline for disinfection and sterilization in healthcare facilities Healthcare infection control practices advisory committee.

View acceseed 27/2/2019.